[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100552372":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":27,"locations":27,"responsibleParty":28,"collaborators":30,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":27,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":27,"enrollmentInfo":63,"targetDuration":27,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":74,"whyStopped":27,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":27},{"fullName":5,"class":6},"Women's Hospital School Of Medicine Zhejiang University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Chloroprocaine group","EXPERIMENTAL","Selection of local anesthetics for epidural labor analgesia with low concentration of chloroprocaine combined with sufentanil",[13],"Drug: Chloroprocaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Ropivacaine group","PLACEBO_COMPARATOR","Selection of local anesthetics for epidural labor analgesia with low concentration of ropivacaine combined with sufentanil",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Chloroprocaine","Selection of low concentration of chloroprocaine as local anesthetic for labor analgesia",[9,15],[26],"Ropivacaine",null,{"type":29,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR",[31,33,35,37,40,42,44,46,48,50,52],{"name":32,"class":6},"Beijing Obstetrics and Gynecology Hospital",{"name":34,"class":6},"International Peace Maternity and Child Health Hospital",{"name":36,"class":6},"Nanjing Medical University",{"name":38,"class":39},"Anhui Women and Children's Medical Center","UNKNOWN",{"name":41,"class":6},"Jiaxing Maternity and Child Health Care Hospital",{"name":43,"class":39},"Gansu Maternal and Child Health Center",{"name":45,"class":39},"Urumqi Maternal and Child Health Center",{"name":47,"class":6},"Shengjing Hospital",{"name":49,"class":6},"Zhongnan Hospital",{"name":51,"class":6},"Second Affiliated Hospital of Wenzhou Medical University",{"name":53,"class":6},"Second Hospital of Jilin University","100552372","phase-4-multicenter-study-of-chloroprocaine-versus-ropivacaine-for-epidural-labor-analgesia-100552372",false,"NCT06472232","Multicenter Study of Chloroprocaine Versus Ropivacaine for Epidural Labor Analgesia","Efficacy and Safety of Chloroprocaine Versus Ropivacaine for Epidural Labor Analgesia Study: a Randomized, Double-blind, Controlled, Multicenter, Noninferiority Clinical Trial","Inclusion Criteria:\n\n* Primigravid women with full-term pregnancies scheduled for labor analgesia\n* Determination of labor onset to cervical dilatation ≤ 5cm;\n* Visual analogue scale (VAS) pain score during contractions \\>50 mm (0 mm = no pain at all, 100 mm = most intense pain);\n* Age ≥20 years;\n* American Society of Anesthesiologists (ASA) classification II\n* Body mass index (BMI) between 18.5 and 30 kg\u002Fm2\n* Height \\>155 cm\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Twin or multiple pregnancies\n* Hypertension\n* Severe cardiopulmonary and hepatic or renal disease\n* Severe pregnancy comorbidities such as preeclampsia, eclampsia, HELLP syndrome, placenta praevia, placental abruption, etc.\n* Cephalopelvic disproportion\n* History of allergy to local anesthesia\n* Spinal deformity\n* Contraindications to intrathecal anesthesia\n* Refusal to participate in the stud","FEMALE","20 Years",{"count":64,"type":65},356,"ESTIMATED","INTERVENTIONAL",[68],"PHASE4","Women requiring epidural labor analgesia were randomized into two groups, one with the local anesthetic chloroprocaine and the other with ropivacaine. The primary outcome was to observe the analgesic scores of the two groups of drugs as well as adverse reactions.",[71],"Obstetric Labor",[73,22,26],"labor analgesia","NOT_YET_RECRUITING","2024-06-21",{"date":77,"type":78},"2024-06-25","ACTUAL",{"date":80,"type":65},"2024-06-18",{"date":82,"type":65},"2025-09-30",{"name":5,"class":6}]