[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100656087":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":13,"armGroups":20,"interventions":39,"overallOfficials":59,"centralContacts":63,"locations":69,"responsibleParty":86,"collaborators":13,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":13,"eligibilityCriteria":95,"healthyVolunteers":91,"sex":96,"minAge":97,"maxAge":13,"enrollmentInfo":98,"targetDuration":13,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":13,"overallStatus":107,"whyStopped":13,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"University of Miami","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Change in Post-Operative Pain Intensity","Pot-operative pain intensity measured using the Numeric Rating Scale (NRS, 0-10), where 0 indicates no pain and 10 indicates worst possible pain; higher scores indicate greater pain following nail unit procedures.","24 hours post nail procedure, 48 hours post nail procedure, 72 hours post nail procedure",null,{"allocation":15,"interventionModel":16,"interventionModelDescription":13,"primaryPurpose":17,"observationalModel":13,"timePerspective":13,"maskingInfo":18},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":19,"maskingDescription":13,"whoMasked":13},"NONE",[21,27,33],{"label":22,"type":23,"description":24,"interventionNames":25},"Suzetrigine Group","EXPERIMENTAL","Participants in this arm will receive suzetrigine for 5 days for post-operative pain management following nail unit procedures.",[26],"Drug: Suzetrigine",{"label":28,"type":29,"description":30,"interventionNames":31},"Oxycodone + Acetaminophen Combination Group","ACTIVE_COMPARATOR","Participants in this arm will receive a combination of oxycodone and acetaminophen for 5 days for post-operative pain management following nail unit procedures.",[32],"Drug: Oxycodone\u002FAcetaminophen",{"label":34,"type":29,"description":35,"interventionNames":36},"Alternating Acetaminophen\u002FIbuprofen Group","Participants in this arm will receive alternating acetaminophen and ibuprofen administered orally every 6 hours for 5 days starting the day of the nail procedure.",[37,38],"Drug: Acetaminophen","Drug: Ibuprofen",[40,45,51,55],{"type":41,"name":42,"description":43,"armGroupLabels":44,"otherNames":13},"DRUG","Suzetrigine","Participants will receive two 50 mg oral tablets on day 1, followed by 50 mg oral tablets every 12 hours for 5 days",[22],{"type":41,"name":46,"description":47,"armGroupLabels":48,"otherNames":49},"Oxycodone\u002FAcetaminophen","Participants will receive oral oxycodone 5 mg\u002Facetaminophen 325 mg (Percocet®) as a fixed-dose combination tablet every 6 hours for 5 days, beginning on the day of the nail procedure.",[28],[50],"Percocet®",{"type":41,"name":52,"description":53,"armGroupLabels":54,"otherNames":13},"Acetaminophen","Participants will receive acetaminophen 650 mg orally every 6 hours, alternating with ibuprofen, for 5 days beginning on the day of the nail procedure.",[34],{"type":41,"name":56,"description":57,"armGroupLabels":58,"otherNames":13},"Ibuprofen","Participants will receive ibuprofen 400 mg orally every 6 hours, alternating with acetaminophen, for 5 days beginning on the day of the nail procedure.",[34],[60],{"name":61,"affiliation":5,"role":62},"Brian Morrison, MD","PRINCIPAL_INVESTIGATOR",[64],{"name":65,"role":66,"phone":67,"phoneExt":13,"email":68},"Brian W Morrison, MD","CONTACT","305-243-4472","bmorrison@med.miami.edu",[70],{"facility":71,"status":13,"city":72,"state":73,"zip":74,"country":75,"countryCode":76,"cosmosGeoPoint":77,"geoPoint":82,"contacts":83},"University of Miami, Phillip Frost Dermatology Clinic","Miami","Florida","33136","United States","US",{"type":78,"coordinates":79},"Point",[80,81],-80.19366,25.77427,{"lat":81,"lon":80},[84,85],{"name":65,"role":66,"phone":67,"phoneExt":13,"email":68},{"name":61,"role":62,"phone":13,"phoneExt":13,"email":13},{"type":62,"investigatorFullName":87,"investigatorTitle":88,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"Brian W Morrison","Associate Professor of Clinical","100656087","phase-4-post-op-analgesia-of-nail-unit-procedures-100656087",false,"NCT07820969","Post-op Analgesia of Nail Unit Procedures","Post-operative Analgesia of Nail Unit Procedures: A Prospective Pilot Study Comparing Suzetrigine vs. Oxycodone+Acetaminophen vs. Acetaminophen\u002FIbuprofen","Inclusion Criteria:\n\n* All patients age 18+ able to understand and provide written consent in English or Spanish who present to Dr. Brian Morrison's clinic at the University of Miami and are undergoing a nail unit procedure.\n\nExclusion Criteria:\n\n* Patients under the age of 18 or adults unable to consent.\n* Patients who are pregnant or incarcerated.","ALL","18 Years",{"count":99,"type":100},45,"ESTIMATED","INTERVENTIONAL",[103],"PHASE4","The purpose of this study is to directly compare the efficacy of suzetrigine vs. oxycodone+acetaminophen vs. alternating acetaminophen\u002Fibuprofen in controlling post-operative pain after the following nail unit procedures.",[106],"Nail Diseases","NOT_YET_RECRUITING","2026-09-29",{"date":110,"type":111},"2026-10-01","ACTUAL",{"date":110,"type":100},{"date":114,"type":100},"2028-10-01",{"name":5,"class":6},1]