[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100378467":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":49,"centralContacts":54,"locations":64,"responsibleParty":78,"collaborators":80,"id":84,"slug":85,"hasResults":86,"nctId":87,"briefTitle":88,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":86,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":58,"studyType":97,"phases":98,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":66,"whyStopped":58,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"Wake Forest University Health Sciences","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Topical steroid plus oral antibiotic group","ACTIVE_COMPARATOR","Participants in this group receive topical steroid (class I-II applied once daily) plus oral antibiotic group (doxycyline 100 mg twice daily for 6 months), and then topical minoxidil (5% solution or foam) after 8 months of treatment.",[13,14,15],"Drug: Topical steroid class I-II","Drug: Doxycyline","Drug: Minoxidil",{"label":17,"type":10,"description":18,"interventionNames":19},"Topical steroid plus intralesional steroid injection group","Participants in this group receive topical steroid (class I-II applied once daily) plus intralesional steroid group (7.5mg\u002Fcc of kenaolog, max dose of 3 cc), and then topical minoxidil (5% solution or foam) after 8 months of treatment",[13,20,15],"Drug: Triamcinolone Acetonide",[22,29,35,43],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DRUG","Topical steroid class I-II","applied once daily - 18 month duration of the study",[17,9],[28],"Clobetasol, Betamethasone Dipropionate, or Fluocinonide",{"type":23,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"Triamcinolone Acetonide","Intralesional Steroid Injection, 7.5mg\u002Fcc. max dose of 3 cc. Scalp injections will be administered every 6-8 weeks, for a total of 8 injections.",[17],[34],"Kenaolog",{"type":23,"name":36,"description":37,"armGroupLabels":38,"otherNames":39},"Doxycyline","oral antibiotic twice daily for 6 months",[9],[40,41,42],"Doxy-100","Targadox","Oracea",{"type":23,"name":44,"description":45,"armGroupLabels":46,"otherNames":47},"Minoxidil","5% solution or foam started after month 8",[17,9],[48],"Rogaine",[50],{"name":51,"affiliation":52,"role":53},"Amy J McMichael, MD","Wake Forest Baptist Health Department of Dermatology","PRINCIPAL_INVESTIGATOR",[55,60],{"name":51,"role":56,"phone":57,"phoneExt":58,"email":59},"CONTACT","336.716.3926",null,"amcmichael@wakehealth.edu",{"name":61,"role":56,"phone":62,"phoneExt":58,"email":63},"Judy Holbrook, CRC","336.716.8991","jholbroo@wakehealth.edu",[65],{"facility":52,"status":66,"city":67,"state":68,"zip":69,"country":70,"countryCode":71,"cosmosGeoPoint":72,"geoPoint":77,"contacts":58},"RECRUITING","Winston-Salem","North Carolina","27157","United States","US",{"type":73,"coordinates":74},"Point",[75,76],-80.24422,36.09986,{"lat":76,"lon":75},{"type":79,"investigatorFullName":58,"investigatorTitle":58,"investigatorAffiliation":58,"oldNameTitle":58,"oldOrganization":58},"SPONSOR",[81],{"name":82,"class":83},"The Skin of Color Society","UNKNOWN","100378467","phase-4-treatment-results-for-patients-with-central-centrifugal-cicatricial-alopecia-ccca-a-multicenter-prospective-study-100378467",false,"NCT04207931","Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study","CCCA","Inclusion Criteria:\n\n* African-American women, ages 18-60 years old\n* with a clinical diagnosis and biopsy-proven CCCA, with Central Scalp Alopecia Scale severity 1 through 4 will be included in this study\n* These subjects will be seen and treated in Wake Forest Baptist Health Dermatology Outpatient Clinic\n\nExclusion Criteria:\n\n* Patients with other forms of hair loss in addition to CCCA will be excluded\n* Other patients to be excluded are those with other forms of inflammatory scalp disease (with the exception of mild seborrheic dermatitis)\n* patients who have had topical treatment for CCCA within the past 4 months (including topical steroids, topical minoxidil, or any other topical hair regrowth medication)\n* patients who have been on a long-term oral antibiotics for hair loss within the past year\n* patients who have undergone more than two rounds of intralesional steroid injections to the scalp in the past one year.","FEMALE","18 Years","60 Years",{"count":95,"type":96},250,"ESTIMATED","INTERVENTIONAL",[99],"PHASE4","The objective of this study is to examine photos of CCCA patients taken before and after treatment to compare treatment outcomes between different treatment groups",[102],"Central Centrifugal Cicatricial Alopecia (CCCA)",[104,105,106,44,107],"alopecia","Hair loss","Female hair loss","Topical Steroid","2026-03-30",{"date":110,"type":111},"2026-03-31","ACTUAL",{"date":113,"type":111},"2018-04-30",{"date":115,"type":96},"2027-03",{"name":5,"class":6},1]