[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100656717":3},{"organization":4,"outcomesModule":7,"designInfo":31,"detailedDescription":30,"studyPopulation":34,"armGroups":35,"interventions":45,"overallOfficials":30,"centralContacts":51,"locations":57,"responsibleParty":72,"collaborators":74,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":30,"enrollmentInfo":89,"targetDuration":30,"studyType":92,"phases":30,"briefSummary":93,"conditions":94,"keywords":30,"overallStatus":97,"whyStopped":30,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Nantes University Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":30},[9],{"measure":10,"description":11,"timeFrame":12},"Blood miR-10a-5p expression","The concentration of each miR-enriched fraction will be determined by spectrophotometric between patients with SA or FA and matched healthy controls.","3 months",[14,17,20,22,24,26,28],{"measure":15,"description":16,"timeFrame":12},"Blood additional circulating miRs expression","The concentration of circulating miRs fraction will be determined by spectrophotometric between patients with SA or FA and matched healthy controls.",{"measure":18,"description":19,"timeFrame":12},"Clinical Characteristics","Association between blood expression levels of circulating miRs and age",{"measure":18,"description":21,"timeFrame":12},"Association between blood expression levels of circulating miRs and sex",{"measure":18,"description":23,"timeFrame":12},"Association between blood expression levels of circulating miRs and duration of addiction",{"measure":18,"description":25,"timeFrame":12},"Association between blood expression levels of circulating miRs and severity of addiction",{"measure":18,"description":27,"timeFrame":12},"Association between blood expression levels of circulating miRs and tobacco-use",{"measure":18,"description":29,"timeFrame":12},"Association between blood expression levels of circulating miRs and psychiatric disorders",null,{"allocation":30,"interventionModel":30,"interventionModelDescription":30,"primaryPurpose":30,"observationalModel":32,"timePerspective":33,"maskingInfo":30},"CASE_CONTROL","PROSPECTIVE","Patients with food or sexual addiction, compared with age- and sex-matched healthy controls with no current addictive disorder.",[36,41],{"label":37,"type":30,"description":38,"interventionNames":39},"Patients with addiction","Patients with food addiction (FA) or sexual addiction",[40],"Biological: blood sampling",{"label":42,"type":30,"description":43,"interventionNames":44},"Healthy controls","Healthy controls matched on sex and age to patients with food addiction or sexual addiction",[40],[46],{"type":47,"name":48,"description":49,"armGroupLabels":50,"otherNames":30},"BIOLOGICAL","blood sampling","One blood sample wiil be collected into a 10mL K2EDTA BD Vacutainer® tube",[42,37],[52],{"name":53,"role":54,"phone":55,"phoneExt":30,"email":56},"Pr Caroline Victorri-Vigneau","CONTACT","02.40.84.76.20","marie.bronnec@chu-nantes.fr",[58],{"facility":5,"status":30,"city":59,"state":30,"zip":30,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"Nantes","France","FR",{"type":63,"coordinates":64},"Point",[65,66],-1.55336,47.21725,{"lat":66,"lon":65},[69],{"name":70,"role":54,"phone":55,"phoneExt":30,"email":71},"Gaëlle CHALLET","gaelle.bouju@chu-nantes.fr",{"type":73,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR",[75],{"name":76,"class":77},"INSERM U1216 Grenoble Institut des Neurosciences","UNKNOWN","100656717","physiopathology-of-behavioral-addictions-and-biomarkers-100656717",false,"NCT07830680","Physiopathology of Behavioral Addictions and Biomarkers","Physiopathology of Behavioral Addictions and Biomarkers: microRNAs Implication - MiRACle : a Pilot Study.","MiRACle","Inclusion criteria\n\nFor patients with FA:\n\n* Male and females ≥ 18 years old\n* Already in care or newly initiating care\n* Participating to EVALADD cohort\n* Current diagnosis of FA\n* Oral consent provided\n* Affiliated with French social security system or beneficiary from such system\n\nFor healthy controls matched to patients with FA:\n\n* Male and females ≥ 18 years old\n* Oral consent provided\n* Affiliated with French social security system or beneficiary from such system\n\nFor patients with SA:\n\n* Male ≥ 18 years old\n* Already in care or newly initiating care\n* Participating to EVALADD cohort\n* Current diagnosis of SA\n* Oral consent provided\n* Affiliated with French social security system or beneficiary from such system\n\nFor healthy controls matched to patients with SA:\n\n* Male ≥ 18 years old\n* Oral consent provided\n* Affiliated with French social security system or beneficiary from such system\n\nExclusion Criteria :\n\nFor patients with FA:\n\n* Presence of a current diagnosis of SA\n* Presence of any current addictive disorder (substance \\[except tobacco\\] use disorders, gambling disorder, gaming disorder)\n* Presence of any current instable psychiatric disorder (requiring the initiation or adapation of medication)\n* Pregnancy or breastfeeding woman\n* Trusteeship or curatorship\n* Major cognitive impairment\n* Not fluent in French\n\nFor patients with SA:\n\n* Presence of a current diagnosis of FA\n* Presence of any current addictive disorder (substance \\[except tobacco\\] use disorders, gambling disorder, gaming disorder)\n* Presence of any current instable psychiatric disorder (requiring the initiation or adapation of medication)\n* Trusteeship or curatorship\n* Major cognitive impairment\n* Not fluent in French\n\nFor healthy controls:\n\n* Without a current diagnosis of FA\n* Without a current diagnosis of SA\n* Presence of any current addictive disorder (substance \\[except tobacco\\] use disorders, gambling disorder, gaming disorder)\n* Presence of any current instable psychiatric disorder (requiring the initiation or adapation of medication)\n* Pregnancy or breastfeeding woman\n* Trusteeship or curatorship\n* Major cognitive impairment\n* Not fluent in French",true,"ALL","18 Years",{"count":90,"type":91},28,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to evaluate the expression of miR-10a-5p in the blood in patients with sexual addiction or food addiction. The main question it aims to answer is : To determine whether adults patients with SA or FA exhibit a distinct blood miR-10a-5p expression profile compared with matched healthy controls.\n\nFor all participants, one blood sample will be collected.",[95,96],"Food Addiction","Sexual Addiction","NOT_YET_RECRUITING","2026-09-21",{"date":100,"type":101},"2026-09-24","ACTUAL",{"date":103,"type":91},"2026-10-01",{"date":105,"type":91},"2028-06-30",{"name":5,"class":6},1]