[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654264":3},{"organization":4,"outcomesModule":7,"designInfo":19,"detailedDescription":18,"studyPopulation":22,"armGroups":18,"interventions":23,"overallOfficials":18,"centralContacts":28,"locations":34,"responsibleParty":50,"collaborators":18,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":18,"eligibilityCriteria":57,"healthyVolunteers":54,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":18,"studyType":64,"phases":18,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":71,"whyStopped":18,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"University of Nebraska","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":18},[9],{"measure":10,"description":11,"timeFrame":12},"Amount of Interleukin-1 beta (IL1-B) in gingival crevicular at baseline","Measurement of IL1B in GCF","Baseline",[14],{"measure":15,"description":16,"timeFrame":17},"Bone Density","Change in bone density post-extraction","3 months",null,{"allocation":18,"interventionModel":18,"interventionModelDescription":18,"primaryPurpose":18,"observationalModel":20,"timePerspective":21,"maskingInfo":18},"COHORT","PROSPECTIVE","Study population will be made of patients at the UNMC College of Dentistry requiring posterior extraction, aged 65-80.",[24],{"type":25,"name":26,"description":27,"armGroupLabels":18,"otherNames":18},"PROCEDURE","tooth extraction","posterior tooth extraction",[29],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},"Amy Killeen, DDS, MS","CONTACT","4024727848","akilleen@unmc.edu",[35],{"facility":36,"status":18,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"University of Nebraska Medical Center College of Dentistry","Lincoln","Nebraska","68583","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-96.66696,40.8,{"lat":46,"lon":45},[49],{"name":30,"role":31,"phone":32,"phoneExt":18,"email":33},{"type":51,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100654264","post-extraction-wound-healing-in-elderly-100654264",false,"NCT07796269","Post-Extraction Wound Healing in Elderly","Inclusion Criteria:\n\n* needs posterior tooth extracted\n* no systemic conditions or meds affecting wound healing\n* non-smoker\n\nExclusion Criteria:\n\n* systemic conditions or meds known to affect wound healing\n* smokers","ALL","65 Years","80 Years",{"count":62,"type":63},72,"ESTIMATED","OBSERVATIONAL","Patients presenting to the University of Nebraska Medical Center College of Dentistry for a posterior extraction will be offered participation in the study. Prior to extraction, subjects will undergo clinical measurements, xray, gingival crevicular fluid (GCF) and saliva sampling and a blood draw. Following atraumatic tooth extraction, the subjects will be reevaluated for healing at 1, 2-weeks and 3 months. At each appointment, GCF, saliva and wound fluid (WF) will be collected and at 3 months a second xray will be taken.",[67],"Wound Healing",[69,70],"extraction","elderly","NOT_YET_RECRUITING","2026-09-10",{"date":74,"type":75},"2026-09-14","ACTUAL",{"date":77,"type":63},"2026-11-01",{"date":79,"type":63},"2030-11-01",{"name":5,"class":6},1]