[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655773":3},{"organization":4,"outcomesModule":7,"designInfo":30,"detailedDescription":33,"studyPopulation":34,"armGroups":35,"interventions":29,"overallOfficials":39,"centralContacts":44,"locations":29,"responsibleParty":50,"collaborators":29,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":29,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":29,"maxAge":62,"enrollmentInfo":63,"targetDuration":66,"studyType":67,"phases":29,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":80,"whyStopped":29,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":29},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":29},[9],{"measure":10,"description":11,"timeFrame":12},"Occurrence of postnatal growth failure","Proportion of preterm infants who develop postnatal growth failure at hospital discharge, defined as discharge weight below the 10th percentile for postmenstrual age according to the Fenton Growth Chart, or a decline in weight-for-age Z-score of more than 1.0 standard deviation between birth and discharge.","Up to 30 days",[14,17,20,23,26],{"measure":15,"description":16,"timeFrame":12},"Growth velocity","Growth velocity expressed as grams per kilogram per day (g\u002Fkg\u002Fday) during hospitalization",{"measure":18,"description":19,"timeFrame":12},"Time to achieve full enteral feeding","Number of days from birth to achievement of full enteral feeding (150 mL\u002Fkg\u002Fday).",{"measure":21,"description":22,"timeFrame":12},"Duration of parenteral nutrition","Number of days of parenteral nutrition during hospitalization.",{"measure":24,"description":25,"timeFrame":12},"Length of hospital stay","Duration of hospitalization in days.",{"measure":27,"description":28,"timeFrame":12},"In-hospital mortality","Rate of mortality during the NICU stay.",null,{"allocation":29,"interventionModel":29,"interventionModelDescription":29,"primaryPurpose":29,"observationalModel":31,"timePerspective":32,"maskingInfo":29},"COHORT","PROSPECTIVE","Postnatal growth failure is a common complication among preterm infants admitted to neonatal intensive care units. This prospective cohort study will include preterm infants (gestational age less than 37 weeks) admitted to the NICU within the first 24 hours of life and hospitalized for at least 14 days.\n\nClinical data, nutritional practices, and serial anthropometric measurements will be collected from admission until hospital discharge. Postnatal growth failure will be defined as a discharge weight below the 10th percentile for postmenstrual age according to the Fenton Growth Chart and\u002For a decline in weight Z-score of more than 1.0 standard deviation between birth and discharge. The study will identify independent clinical and nutritional predictors of postnatal growth failure.","Preterm infants admitted to the Neonatal Intensive Care Unit of Assiut University Children's Hospital.",[36],{"label":37,"type":29,"description":38,"interventionNames":29},"Single cohort: Preterm infants admitted to NICU","Preterm infants with gestational age less than 37 weeks admitted to the NICU within 24 hours of birth and hospitalized for at least 14 days, followed until hospital discharge for assessment of postnatal growth failure and its predictors.",[40],{"name":41,"affiliation":42,"role":43},"Kotb A Metwalley, prof","pediatrics Department, Assiut University Hospitals","STUDY_CHAIR",[45],{"name":46,"role":47,"phone":48,"phoneExt":29,"email":49},"Kamal G Ahmed, Resident","CONTACT","+20 11 41620746","kamal.18313193@med.aun.edu.eg",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"PRINCIPAL_INVESTIGATOR","Kamal Gamal Mohamed Ahmed","Resident Physician, Department of pediatrics","100655773","predictors-of-postnatal-growth-failure-in-preterm-infants-100655773",false,"NCT07818681","Predictors of Postnatal Growth Failure in Preterm Infants","Clinical and Nutritional Predictors of Postnatal Growth Failure in Preterm Infants Admitted to the Neonatal Intensive Care Unit of Assiut University Children's Hospital","Inclusion Criteria:\n\n* \\- Gestational age less than 37 completed weeks\n* Admission to the NICU within the first 24 hours after birth\n* Hospitalization for at least 14 days\n* Availability of complete clinical, nutritional, and anthropometric data\n* Written informed consent from parents or legal guardians\n\nExclusion Criteria:\n\n* \\- Major congenital malformations\n* Chromosomal abnormalities\n* Major congenital gastrointestinal anomalies interfering with feeding\n* Major congenital heart diseases requiring early surgical intervention\n* Inborn errors of metabolism\n* Congenital TORCH infections","ALL","36 Weeks",{"count":64,"type":65},120,"ESTIMATED","30 Days","OBSERVATIONAL","This prospective observational study aims to identify the clinical and nutritional predictors of postnatal growth failure among preterm infants admitted to the Neonatal Intensive Care Unit of Assiut University Children's Hospital.",[70,71,72],"Premature Birth","Growth Failure","Very Low Birth Weight Infant",[74,75,76,77,78,79],"Clinical predictors","Postnatal growth failure","Preterm infants","Neonatal intensive care","Nutritional predictors","Assiut","NOT_YET_RECRUITING","2026-09-10",{"date":83,"type":84},"2026-09-14","ACTUAL",{"date":86,"type":65},"2026-09-20",{"date":88,"type":65},"2028-07-01",{"name":5,"class":6}]