[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659911":3},{"organization":4,"outcomesModule":7,"designInfo":40,"detailedDescription":43,"studyPopulation":44,"armGroups":45,"interventions":39,"overallOfficials":49,"centralContacts":53,"locations":58,"responsibleParty":75,"collaborators":39,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":93,"studyType":94,"phases":39,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":102,"whyStopped":39,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Izmir Democracy University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":39},[9],{"measure":10,"description":11,"timeFrame":12},"Diet Inflammatory Index","The Dietary Inflammatory Index will be calculated for patients with premature ventricular complexes","From enrollment to the end of treatment at 2 years",[14,17,20,23,26,28,30,32,34,36],{"measure":15,"description":16,"timeFrame":12},"Diet Quality","Diet quality will be assessed using the Diet Quality Index-International (DQI-I) scoring system",{"measure":18,"description":19,"timeFrame":12},"Food Variety","Participants' dietary variety will be determined using 3-day dietary records",{"measure":21,"description":22,"timeFrame":12},"Glucose","Serum glucose will be obtained from the participants' routine blood parameters.",{"measure":24,"description":25,"timeFrame":12},"Hemoglobin A1c","The data will be obtained from the participants' routine blood test results.",{"measure":27,"description":25,"timeFrame":12},"Total Cholesterol",{"measure":29,"description":25,"timeFrame":12},"High Density Lipoprotein",{"measure":31,"description":25,"timeFrame":12},"Low Density Lipoprotein",{"measure":33,"description":25,"timeFrame":12},"Trygliseride",{"measure":35,"description":25,"timeFrame":12},"Vitamin D",{"measure":37,"description":38,"timeFrame":12},"Life Quality","The Short Form-36 Health Survey will be used to assess the participants' quality of life.",null,{"allocation":39,"interventionModel":39,"interventionModelDescription":39,"primaryPurpose":39,"observationalModel":41,"timePerspective":42,"maskingInfo":39},"CASE_CONTROL","CROSS_SECTIONAL","Although premature ventricular contractions are among the most common types of arrhythmia in patients both with and without structural heart disease, they may lead to long-term left ventricular dysfunction in patients with structurally normal hearts. An increased frequency of premature ventricular complexes (PVCs) may be associated with mental and physical stress, lifestyle-related factors, as well as cardiovascular risk factors such as hypertension, dyslipidemia, diabetes mellitus, and coronary artery disease. Frequent PVCs may lead to tachycardiomyopathy and, consequently, increased morbidity and mortality. The aim of this study is to evaluate differences in energy, macro- and micronutrient intakes, dietary characteristics, quality of life, and biochemical parameters between individuals with and without premature ventricular complexes. The study will include a total of 100 adults who present to the Cardiology Outpatient Clinic of Buca Seyfi Demirsoy Training and Research Hospital, comprising 50 individuals with premature ventricular complexes and 50 healthy individuals. Participants will be instructed to discontinue caffeine-containing beverages, stimulants, and medications that may affect cardiac rhythm for 72 hours prior to Holter monitoring. The diagnosis of premature ventricular complexes will be established by a specialist cardiologist. Dietary intake will be assessed using three non-consecutive 24-hour dietary recalls, including two weekdays and one weekend day. Dietary intake data will be collected by the researcher through face-to-face interviews and recorded on the study questionnaire. The Dietary Inflammatory Index (DII) and Healthy Eating Index will be calculated based on the participants' three-day dietary intake data. No additional blood samples or biochemical tests will be requested specifically for the purposes of this study. Instead, the participants' most recent biochemical parameters obtained as part of routine clinical care will be retrieved from their medical records. These parameters will include fasting blood glucose (mg\u002FdL), glycated hemoglobin (HbA1c, %), total cholesterol (mg\u002FdL), high-density lipoprotein cholesterol (HDL-C, mg\u002FdL), low-density lipoprotein cholesterol (LDL-C, mg\u002FdL), triglycerides (mg\u002FdL), vitamin D, and other routinely assessed biochemical parameters. The results will be interpreted according to the reference ranges used by Buca Seyfi Demirsoy Training and Research Hospital. Participants' quality of life will be assessed using the 36-Item Short Form Health Survey (SF-36).","The study will include 50 individuals with premature ventricular complexes (PVCs) and 50 healthy adults who present to the Cardiology Outpatient Clinic of Buca Seyfi Demirsoy Training and Research Hospital. Participants will be asked to discontinue caffeine-containing beverages, stimulants, and medications that may affect cardiac rhythm for 72 hours prior to Holter monitoring. The diagnosis of premature ventricular complexes will be established by a specialist cardiologist.",[46],{"label":47,"type":39,"description":48,"interventionNames":39},"Patients of Premature Ventricular Complex","The study will include 50 individuals with premature ventricular complexes who present to the Cardiology Outpatient Clinic of Buca Seyfi Demirsoy Training and Research Hospital.",[50],{"name":51,"affiliation":5,"role":52},"Kerim K GÖKÜSTÜN, PhD","PRINCIPAL_INVESTIGATOR",[54],{"name":51,"role":55,"phone":56,"phoneExt":39,"email":57},"CONTACT","05058699031","kerimkaangokustun@hotmail.com",[59],{"facility":60,"status":39,"city":61,"state":39,"zip":62,"country":63,"countryCode":39,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"Buca Seyfi Demirsoy Training and Research Hospital","Izmir","35310","Turkey (Türkiye)",{"type":65,"coordinates":66},"Point",[67,68],27.13838,38.41273,{"lat":68,"lon":67},[71],{"name":72,"role":55,"phone":73,"phoneExt":39,"email":74},"Erkan ALPASLAN, PhD","05057908262","erkan8721@gmail.com",{"type":52,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":39,"oldOrganization":39},"Kerim Kaan Göküstün","Asistant Professor","100659911","premature-ventricular-complex-and-diet-inflamatuar-index-100659911",false,"NCT07870109","Premature Ventricular Complex and Diet Inflamatuar Index","Comparison of Dietary Inflammatory Index, Quality of Life, and Biochemical Parameters Between Individuals With and Without Premature Ventricular Complexes","PVT","Inclusion Criteria:\n\nInclusion criteria for individuals with premature ventricular complexes (PVCs):\n\n* Being between 18 and 80 years of age.\n* Having \\>10,000 PVCs\u002Fday, as determined by 24-hour Holter monitoring.\n\nInclusion criteria for healthy individuals:\n\n* Being between 18 and 80 years of age.\n* Having \\\u003C10,000 PVCs\u002Fday, as determined by 24-hour Holter monitoring.\n\nExclusion Criteria:\n\nExclusion criteria for individuals with premature ventricular complexes (PVC):\n\n* Having an active infection,\n* Having tachycardia due to secondary causes,\n* Having congestive heart failure (including PVC-induced tachycardiomyopathy),\n* Having symptomatic congenital heart disease,\n* Having symptomatic valvular heart disease,\n* Having diagnosed coronary artery disease,\n* Having a diagnosed psychiatric disorder,\n* Having an eating disorder such as anorexia nervosa or bulimia nervosa.\n\nExclusion criteria for healthy individuals:\n\n* Being \\\u003C18 or \\>80 years of age,\n* Having an active infection,\n* Having tachycardia due to secondary causes,\n* Having congestive heart failure (including PVC-induced tachycardiomyopathy),\n* Having symptomatic congenital heart disease,\n* Having symptomatic valvular heart disease,\n* Having diagnosed coronary artery disease,\n* Having a diagnosed psychiatric disorder,\n* Having an eating disorder such as anorexia nervosa or bulimia nervosa.",true,"ALL","18 Years","80 Years",{"count":91,"type":92},100,"ESTIMATED","2 Years","OBSERVATIONAL","The aim of this study is to evaluate differences in energy, macro- and micronutrient intakes, dietary characteristics, quality of life, and biochemical parameters between individuals with and without premature ventricular complexes. The study will include a total of 100 adults who present to the Cardiology Outpatient Clinic of Buca Seyfi Demirsoy Training and Research Hospital, comprising 50 individuals with premature ventricular complexes and 50 healthy individuals. Participants will be instructed to discontinue caffeine-containing beverages, stimulants, and medications that may affect cardiac rhythm for 72 hours prior to Holter monitoring. The diagnosis of premature ventricular complexes will be established by a specialist cardiologist. Dietary intake will be assessed using three non-consecutive 24-hour dietary recalls, including two weekdays and one weekend day. Dietary intake data will be collected by the researcher through face-to-face interviews and recorded on the study questionnaire. The Dietary Inflammatory Index (DII) and Healthy Eating Index will be calculated based on the participants' three-day dietary intake data. No additional blood samples or biochemical tests will be requested specifically for the purposes of this study. Instead, the participants' most recent biochemical parameters obtained as part of routine clinical care will be retrieved from their medical records. These parameters will include fasting blood glucose (mg\u002FdL), glycated hemoglobin (HbA1c, %), total cholesterol (mg\u002FdL), high-density lipoprotein cholesterol (HDL-C, mg\u002FdL), low-density lipoprotein cholesterol (LDL-C, mg\u002FdL), triglycerides (mg\u002FdL), vitamin D, and other routinely assessed biochemical parameters. The results will be interpreted according to the reference ranges used by Buca Seyfi Demirsoy Training and Research Hospital. Participants' quality of life will be assessed using the 36-Item Short Form Health Survey (SF-36).",[97,15,98,37],"Premature Ventricular Complexes","Biochemical Markers",[100,10,37,101],"Premature Ventricular Complex","Blood Parameters","NOT_YET_RECRUITING","2026-10-06",{"date":105,"type":106},"2026-10-13","ACTUAL",{"date":108,"type":92},"2026-11-15",{"date":110,"type":92},"2027-11-15",{"name":5,"class":6},1]