[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100651800":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":46,"collaborators":49,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":18,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":18,"enrollmentInfo":61,"targetDuration":18,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":80,"whyStopped":18,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Akdeniz University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Preoperative Breathing Exercise Training","EXPERIMENTAL","Participants randomized to this arm will receive standardized preoperative deep breathing exercise training, generally approximately one week before surgery. They will be instructed to perform the exercises three times daily until the day of surgery, with 10 deep breaths in each session. Adherence will be recorded using a home breathing exercise follow-up form.",[13],"Behavioral: Preoperative Deep Breathing Exercise Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Participants randomized to this arm will receive routine preoperative information and standard perioperative care without additional structured preoperative breathing exercise training.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Preoperative Deep Breathing Exercise Training","Participants will receive standardized, device-free deep breathing exercise training during the preoperative period. In an upright or semi-upright position, participants will be instructed to relax their shoulders, inhale slowly and deeply through the nose, hold their breath for approximately 2-3 seconds, and then exhale slowly through the mouth. Each session will consist of 10 deep breaths. Participants will be asked to perform three sessions per day from the time of training until surgery. Exercise adherence will be documented using a home follow-up form and reviewed on the morning of surgery.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"ALİ DEMİRTAŞ, Lucterer","CONTACT","+905322568442","alidemirtas@akdeniz.edu.tr",[32],{"facility":5,"status":18,"city":33,"state":33,"zip":34,"country":35,"countryCode":18,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Antalya","(532) 256-8442","Turkey (Türkiye)",{"type":37,"coordinates":38},"Point",[39,40],30.69556,36.90812,{"lat":40,"lon":39},[43],{"name":44,"role":28,"phone":45,"phoneExt":18,"email":30},"ALİ DEMİRTAŞ","05322568442",{"type":47,"investigatorFullName":44,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","Lecturer",[50],{"name":51,"class":6},"The Scientific and Technological Research Council of Turkey","100651800","preoperative-breathing-exercise-training-and-postoperative-delirium-after-robotic-radical-prostatectomy-100651800",false,"NCT07766603","Preoperative Breathing Exercise Training and Postoperative Delirium After Robotic Radical Prostatectomy","Effect of Preoperative Breathing Exercise Training on Postoperative Delirium in Patients Undergoing Robot-Assisted Radical Prostatectomy: A Randomized Controlled Pilot Study","Inclusion Criteria:\n\n* Male patients aged 40 years or older.\n* Scheduled to undergo elective robot-assisted radical prostatectomy (RARP) at -Akdeniz University Hospital.\n* Able to communicate and suitable for preoperative and postoperative -cognitive\u002Fdelirium assessment using the 4AT and Nu-DESC.\n* Able and willing to provide written informed consent.\n* Availability of clinical follow-up data during the first 48 postoperative hours.\n\nExclusion Criteria:\n\n* Refusal to participate or withdrawal of informed consent.\n* History of delirium, severe dementia, severe cognitive impairment, or an active neurological disorder that would interfere with delirium assessment.\n* Active psychosis, severe psychiatric disease, or use of psychoactive medication that could substantially affect cognitive assessment.\n* Level of consciousness not allowing assessment, or severe hearing or speech impairment preventing adequate communication.\n* Emergency surgery or failure to complete the planned procedure as robot-assisted radical prostatectomy.\n* Inability to complete the postoperative 4AT and\u002For Nu-DESC assessments or substantial missing data affecting the primary analysis.\n* Inability to tolerate the breathing exercises or insufficient home exercise adherence\u002Ffollow-up data for the planned analysis.","MALE","40 Years",{"count":62,"type":63},50,"ESTIMATED","INTERVENTIONAL",[66],"NA","Postoperative delirium is an acute and fluctuating disturbance in attention, awareness, and thinking that may occur after major surgery. Patients undergoing robot-assisted radical prostatectomy may be at risk because of factors such as older age, general anesthesia, prolonged surgery, pneumoperitoneum, and steep Trendelenburg positioning.\n\nThis single-center, prospective, two-arm controlled pilot study will evaluate whether preoperative deep breathing exercise training is associated with a lower occurrence of postoperative delirium in patients undergoing elective robot-assisted radical prostatectomy. A total of 50 patients will be included, with 25 patients in the breathing exercise training group and 25 patients in the control group.\n\nPatients in the breathing exercise training group will receive standardized, device-free deep breathing exercise instruction during the preoperative period, usually approximately one week before surgery. They will be asked to perform three sessions per day until surgery, with 10 deep breaths in each session. Patients in the control group will receive routine preoperative information without additional structured breathing exercise training.\n\nPostoperative delirium will be assessed during the first 48 hours after surgery using the 4AT and Nursing Delirium Screening Scale (Nu-DESC). The study will also evaluate postoperative oxygenation, oxygen requirement, pain, nausea and vomiting, respiratory complications, intensive care requirement, and length of hospital stay. The study will not alter routine anesthesia, surgery, or postoperative treatment, and no additional invasive procedures, laboratory tests, or imaging will be performed for research purposes.",[69,70],"Postoperative Delirium (POD)","Prostate Cancer",[72,73,74,75,76,77,78,79],"Robot-Assisted Radical Prostatectomy","RARP","Preoperative Breathing Exercise","Deep Breathing Exercise","Postoperative Delirium","4AT","Nu-DESC","Pneumoperitoneum","NOT_YET_RECRUITING","2026-08-11",{"date":83,"type":84},"2026-08-14","ACTUAL",{"date":86,"type":63},"2026-09",{"date":88,"type":63},"2027-08",{"name":44,"class":6},1]