[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647626":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":45,"centralContacts":50,"locations":55,"responsibleParty":111,"collaborators":35,"id":113,"slug":114,"hasResults":115,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":119,"eligibilityCriteria":120,"healthyVolunteers":115,"sex":121,"minAge":122,"maxAge":35,"enrollmentInfo":123,"targetDuration":35,"studyType":126,"phases":127,"briefSummary":129,"conditions":130,"keywords":35,"overallStatus":99,"whyStopped":35,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":141},{"fullName":5,"class":6},"Universidade do Porto","OTHER",[8,14,19,25],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of care","ACTIVE_COMPARATOR","Participants receive standard clinical evaluation and management in primary care without NT-proBNP testing and without point-of-care ultrasound (POCUS).",[13],"Other: standard of care",{"label":15,"type":10,"description":16,"interventionNames":17},"Standard of care + NT-proBNP","Participants receive standard clinical evaluation and management in primary care with NT-proBNP testing, but without point-of-care ultrasound (POCUS).",[18,13],"Diagnostic Test: NT-proBNP testing",{"label":20,"type":21,"description":22,"interventionNames":23},"Standard of care + NT-proBNP + POCUS","EXPERIMENTAL","Participants receive standard clinical evaluation and management in primary care with NT-proBNP testing and cardiac point-of-care ultrasound (POCUS).",[18,24,13],"Device: Cardiac Point-of-Care Ultrasound (POCUS)",{"label":26,"type":21,"description":27,"interventionNames":28},"Standard of care + POCUS","Participants receive standard clinical evaluation and management in primary care with cardiac point-of-care ultrasound (POCUS), but without NT-proBNP testing.",[24,13],[30,36,41],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"DIAGNOSTIC_TEST","NT-proBNP testing","Measurement of N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in blood as part of the diagnostic evaluation for suspected heart failure in primary care.",[15,20],null,{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":35},"DEVICE","Cardiac Point-of-Care Ultrasound (POCUS)","Cardiac point-of-care ultrasound performed by trained primary care physicians to assess cardiac structure and function as part of the diagnostic evaluation for suspected heart failure.",[20,26],{"type":6,"name":42,"description":43,"armGroupLabels":44,"otherNames":35},"standard of care","Usual clinical evaluation and management in primary care according to standard practice, without additional diagnostic interventions specified in the study.",[9,15,20,26],[46],{"name":47,"affiliation":48,"role":49},"Jonathan dos Santos","Aveiro University","PRINCIPAL_INVESTIGATOR",[51],{"name":52,"role":53,"phone":35,"phoneExt":35,"email":54},"Jonathan dos Santos, MD.","CONTACT","jonathan.santos@ua.pt",[56,74,87,97],{"facility":57,"status":58,"city":59,"state":35,"zip":35,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"Unidade de Saúde Familiar Conde da Lousã","NOT_YET_RECRUITING","Amadora","Portugal","PT",{"type":63,"coordinates":64},"Point",[65,66],-9.23083,38.75382,{"lat":66,"lon":65},[69],{"name":70,"role":53,"phone":71,"phoneExt":72,"email":73},"Miguel Henriques","914 338 519","(+351)","miguelcachinho@gmail.com",{"facility":75,"status":58,"city":76,"state":35,"zip":35,"country":60,"countryCode":61,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Unidade de Saúde Familiar do Parque","Lisbon",{"type":63,"coordinates":78},[79,80],-9.1498,38.72509,{"lat":80,"lon":79},[83],{"name":84,"role":53,"phone":85,"phoneExt":72,"email":86},"Joana Gonçalves","961 703 789","joana.goncalves@ulssm.min-saude.pt",{"facility":88,"status":58,"city":76,"state":35,"zip":35,"country":60,"countryCode":61,"cosmosGeoPoint":89,"geoPoint":91,"contacts":92},"Unidade de Saúde Familiar Rodrigues Miguéis",{"type":63,"coordinates":90},[79,80],{"lat":80,"lon":79},[93],{"name":94,"role":53,"phone":95,"phoneExt":72,"email":96},"Inês Santos","911 178 033","inessalmeidasantos@gmail.com",{"facility":98,"status":99,"city":100,"state":35,"zip":35,"country":60,"countryCode":61,"cosmosGeoPoint":101,"geoPoint":105,"contacts":106},"Unidade de Saúde Familiar Garcia Orta","RECRUITING","Porto",{"type":63,"coordinates":102},[103,104],-8.61097,41.1485,{"lat":104,"lon":103},[107],{"name":108,"role":53,"phone":109,"phoneExt":72,"email":110},"Rita Queirós","917 257 162","queiros.rita.ana@gmail.com",{"type":112,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR","100647626","primary-hf-heart-failure-screening-in-primary-care-using-point-of--care-100647626",false,"NCT07711821","PRIMARY-HF: Heart Failure Screening in Primary Care Using Point-of- Care","PRIMARY-HF: Diagnóstico de Insuficiência Cardíaca em Cuidados de Saúde Primários Utilizando Ecografia Point-of-Care e Péptidos Natriuréticos","PRIMARY-HF","Inclusion Criteria:\n\n* Adults aged ≥50 years\n* Suspected heart failure (based on signs and\u002For symptoms) OR\n* Presence of at least two cardiovascular risk factors, including:\n\n  1. Diabetes mellitus\n  2. Arterial hypertension\n  3. Estimated glomerular filtration rate (eGFR) \\\u003C60 mL\u002Fmin\u002F1.73 m²\n  4. Albuminuria\n  5. Coronary artery disease or prior myocardial infarction or coronary revascularization\n  6. Stroke or transient ischemic attack\n  7. Atrial fibrillation or flutter\n  8. Left ventricular hypertrophy or Q waves on electrocardiogram\n  9. Obesity (body mass index ≥30 kg\u002Fm²)\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Known heart failure under active hospital-based follow-up\n* Terminal illness or life expectancy \\\u003C1 year\n* Severe comorbid conditions limiting participation or follow-up\n* Inability to provide informed consent","ALL","49 Years",{"count":124,"type":125},160,"ESTIMATED","INTERVENTIONAL",[128],"NA","The goal of this clinical trial is to evaluate whether the use of NT-proBNP testing and point-of-care ultrasound (POCUS) can improve the diagnosis and management of heart failure in adults aged 50 years or older with suspected heart failure or cardiovascular risk factors in primary care settings.\n\nThe main questions it aims to answer are:\n\n* Does the use of NT-proBNP and\u002For POCUS increase the rate of new heart failure diagnoses compared with standard care?\n* Does this approach support earlier initiation of guideline-directed medical therapy and improve patients' quality of life?\n\nResearchers will compare standard care alone with standard care combined with NT-proBNP testing, POCUS, or both, to assess their impact on diagnosis and management of heart failure.\n\nParticipants will:\n\n* Be randomly assigned to one of four groups (standard care, NT-proBNP, POCUS, or both).\n* Undergo clinical evaluation for heart failure according to their assigned group.\n* Be followed for 12 months with periodic assessments of quality of life and treatment adherence.",[131],"Heart Failure","2026-07-13",{"date":134,"type":135},"2026-07-17","ACTUAL",{"date":137,"type":135},"2026-03-23",{"date":139,"type":125},"2027-07",{"name":5,"class":6},4]