[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635372":3},{"organization":4,"outcomesModule":7,"designInfo":21,"detailedDescription":24,"studyPopulation":25,"armGroups":26,"interventions":20,"overallOfficials":20,"centralContacts":33,"locations":43,"responsibleParty":60,"collaborators":20,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":20,"enrollmentInfo":74,"targetDuration":20,"studyType":77,"phases":20,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":85,"whyStopped":20,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":20},[9],{"measure":10,"description":11,"timeFrame":12},"Process-Based Assessment Tool","The scale involves the depiction of psychological and behavioral processes involved in adaptation and maladaptation, according to the Extended Evolutionary Meta-Model.\n\nThe scale includes 18 items, each involving a stand-alone, individual score, indicating the degree to which the responder engages in the specific process. The scale comprises both positive and negative behavioral strategies.","After enrollment (single time point).",[14,17],{"measure":15,"description":16,"timeFrame":12},"Patient Health Questionnaire-9 (PHQ-9)","The scale involves the assessment of depressive symptoms, with a score range between 0 and 27. Scores between 5 and 9 mean mild depression, 10 to 14 moderate depression, 15 to 19 moderate to severe depression and above 20 severe depression (Kroenke et al., 2001).",{"measure":18,"description":19,"timeFrame":12},"Generalized Anxiety Disorder-7 (GAD-7)","The scale involves the assessment of anxiety symptoms, with a score range from 0 to 21. Scores between 5 and 9 indicate mild anxiety, scores between 10 and 14 moderate anxiety, while those above 15 show severe anxiety.",null,{"allocation":20,"interventionModel":20,"interventionModelDescription":20,"primaryPurpose":20,"observationalModel":22,"timePerspective":23,"maskingInfo":20},"CASE_CONTROL","CROSS_SECTIONAL","The present study is grounded in the process-based approach to psychopathology, which emphasizes the identification and modification of core psychological processes underlying mental disorders, rather than focusing exclusively on categorical diagnoses.\n\nA central theoretical framework guiding this approach is the Extended Evolutionary Meta-Model (EEMM), which conceptualizes psychological functioning and psychopathology through evolutionary principles:\n\n* Variation - the ability to generate flexible and adaptive behavioral responses\n* Selection - the capacity to choose behaviors aligned with personal goals and contextual demands\n* Retention - the maintenance and consolidation of adaptive behaviors over time\n* Context - sensitivity to environmental and situational factors influencing behavior\n\nAccording to this model, psychopathology (including Alcohol Use Disorder) is characterized by psychological inflexibility, maladaptive behavioral selection, and poor retention of functional strategies, often in interaction with contextual insensitivity.\n\nThese processes operate across multiple domains, including affect, cognition, attention, motivation, self, and overt behavior.","Primary care clinic, community sample.",[27,30],{"label":28,"type":20,"description":29,"interventionNames":20},"Clinical","AUD diagnosis",{"label":31,"type":20,"description":32,"interventionNames":20},"Control","Healthy participants",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":20,"email":38},"Octavian C. Popa, Assoc.Prof.","CONTACT","+40745092686","cosmin.popa@umfst.ro",{"name":40,"role":36,"phone":41,"phoneExt":20,"email":42},"Cristiana M. Cojocaru, Lecturer","+4-757867711","cristiana-manuela.cojocaru@umfst.ro",[44],{"facility":45,"status":20,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"George Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures","Târgu Mureş","Mureș County","540142","Romania","RO",{"type":52,"coordinates":53},"Point",[54,55],24.55747,46.54245,{"lat":55,"lon":54},[58],{"name":35,"role":36,"phone":37,"phoneExt":20,"email":59},"cristianacojocaru28@gmail.com",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Octavian Cosmin Popa","Associate Professor Dr.","100635372","process-based-psychological-processes-in-alcohol-use-disorder-a-case-control-study-using-pbat-phq-9-and-gad-7-100635372",false,"NCT07551830","Process-Based Psychological Processes in Alcohol Use Disorder: A Case-Control Study Using PBAT, PHQ-9, and GAD-7","PBAT Addiction","Inclusion Criteria:\n\n* age ≥18, the ability to provide informed consent, no psychiatric diagnosis (for the control group).\n\nExclusion Criteria:\n\n* severe cognitive impairment, psychosis, inability to complete questionnaires.",true,"ALL","18 Years",{"count":75,"type":76},200,"ESTIMATED","OBSERVATIONAL","This observational study investigates differences in psychological processes and emotional symptoms between individuals with Alcohol Use Disorder (AUD) and a non-clinical control group. PBAT, PHQ-9, and GAD-7 will be used. MANCOVA will test group differences controlling for demographics.",[80],"Alcohol Use Disorder (AUD)",[80,82,83,84],"Process-Based Assessment Tool (PBAT)","depression","anxiety","NOT_YET_RECRUITING","2026-09-08",{"date":88,"type":89},"2026-09-11","ACTUAL",{"date":91,"type":76},"2026-10",{"date":93,"type":76},"2028-06",{"name":5,"class":6},1]