[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551838":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":51,"centralContacts":56,"locations":62,"responsibleParty":81,"collaborators":83,"id":86,"slug":87,"hasResults":88,"nctId":89,"briefTitle":90,"officialTitle":90,"acronym":30,"eligibilityCriteria":91,"healthyVolunteers":88,"sex":92,"minAge":93,"maxAge":94,"enrollmentInfo":95,"targetDuration":30,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":104,"overallStatus":64,"whyStopped":30,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"University of Maryland, Baltimore","OTHER",[8,16],{"label":9,"type":10,"description":11,"interventionNames":12},"Study group - Intensive ankle\u002Fhand robot rehab","EXPERIMENTAL","Ankle\u002FHand robot with motor relearning with real-time feedback, passive stretching under intelligent control; Active movement training with robotic assistance",[13,14,15],"Device: Motor relearning training with wearable ankle robot","Device: Passive stretching with wearable ankle robot","Device: Gamed-based active movement training with wearable ankle robot",{"label":17,"type":18,"description":19,"interventionNames":20},"Control group - Mild ankle\u002Fhand robot rehab","ACTIVE_COMPARATOR","The same wearable robot used by the study group will be used for the control group but in a limited way: no motor relearning training under real-time feedback; passive movement in the joint middle range of motion instead of passive stretching; active movement training with no robotic assistance",[21,22,23],"Device: Passive movement with limited wearable ankle robot","Device: Active movement training with limited wearable ankle robot","Device: Ankle\u002FWrist torque and motion measurement with limited wearable ankle\u002Fwrist robot",[25,31,35,39,43,47],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DEVICE","Motor relearning training with wearable ankle robot","Ankle motor control relearning training under real-time feedback",[9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"Passive stretching with wearable ankle robot","Passive stretching under intelligent robotic control",[9],{"type":26,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"Gamed-based active movement training with wearable ankle robot","Active movement training through movement games with robotic assistance",[9],{"type":26,"name":40,"description":41,"armGroupLabels":42,"otherNames":30},"Passive movement with limited wearable ankle robot","Passive movement in the joint middle range of motion",[17],{"type":26,"name":44,"description":45,"armGroupLabels":46,"otherNames":30},"Active movement training with limited wearable ankle robot","Active movement training without robotic assistance",[17],{"type":26,"name":48,"description":49,"armGroupLabels":50,"otherNames":30},"Ankle\u002FWrist torque and motion measurement with limited wearable ankle\u002Fwrist robot","Ankle\u002FWrist torque and motion measurement with no real-time feedback",[17],[52],{"name":53,"affiliation":54,"role":55},"Li-Qun Zhang","University of Maryland","PRINCIPAL_INVESTIGATOR",[57],{"name":58,"role":59,"phone":60,"phoneExt":30,"email":61},"Soh-Hyun Hur","CONTACT","410 706-8625","SoHur@som.umaryland.edu",[63],{"facility":53,"status":64,"city":65,"state":66,"zip":67,"country":68,"countryCode":69,"cosmosGeoPoint":70,"geoPoint":75,"contacts":76},"RECRUITING","Baltimore","Maryland","21201","United States","US",{"type":71,"coordinates":72},"Point",[73,74],-76.61219,39.29038,{"lat":74,"lon":73},[77],{"name":78,"role":59,"phone":79,"phoneExt":30,"email":80},"Li-Qun Zhang, PhD","4107062145","l-zhang@som.umaryland.edu",{"type":55,"investigatorFullName":53,"investigatorTitle":82,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Professor",[84],{"name":85,"class":6},"The University of Texas Health Science Center, Houston","100551838","promoting-neuroplastic-changes-of-patients-with-tbi-100551838",false,"NCT06465290","Promoting Neuroplastic Changes of Patients With TBI","Inclusion Criteria:\n\n* Acute first time unilateral hemispheric stroke (hemorrhagic or ischemic stroke, 24 hours after admission to 1 month post-stroke at the start of the proposed treatment)\n* Hemiplegia or hemiparesis\n* 0≤Manual Muscle Testing (MMT)\\\u003C=2\n* Age 30-85\n* Ankle impairments including stiff calf muscles and\u002For inadequate dorsiflexion\n\nExclusion Criteria:\n\n* Medically not stable\n* Associated acute medical illness that interferes with ability to training and exercise\n* No impairment or very mild ankle impairment of ankle\n* Severe cardiovascular problems that interfere with ability to perform moderate movement exercises\n* Cognitive impairment or aphasia with inability to follow instructions\n* Severe pain in legs\n* Severe ankle contracture greater than 15° plantar flexion (when pushing ankle to dorsiflexion)\n* Pressure ulcer, recent surgical incision or active skin disease with open wounds present below knee","ALL","30 Years","85 Years",{"count":96,"type":97},100,"ESTIMATED","INTERVENTIONAL",[100],"NA","This project will develop a wearable rehabilitation robot suitable for in-bed acute stage rehabilitation. It involves robot-guided motor relearning, passive and active motor-sensory rehabilitation early in the acute stage post-TBI including patients who are paralyzed with no motor output. The early acute TBI rehabilitation device will be evaluated in this clinical trial.",[103],"Traumatic Brain Injury",[105,106,107],"Traumatic Brain Injury (TBI)","Paraplegia","Acute","2026-07-15",{"date":110,"type":111},"2026-07-17","ACTUAL",{"date":113,"type":111},"2026-07-16",{"date":115,"type":97},"2030-08-31",{"name":5,"class":6},1]