[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655014":3},{"organization":4,"outcomesModule":7,"designInfo":23,"detailedDescription":26,"studyPopulation":27,"armGroups":28,"interventions":35,"overallOfficials":46,"centralContacts":50,"locations":56,"responsibleParty":73,"collaborators":22,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":22,"eligibilityCriteria":80,"healthyVolunteers":77,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":87,"studyType":88,"phases":22,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":59,"whyStopped":22,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Research Inc","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":22},[9],{"measure":10,"description":11,"timeFrame":12},"Change in Mean Bilateral Popliteal Vein Diameter","At each visit, the mean of three anteroposterior diameter measurements in each leg will be calculated, followed by the mean of both legs. Change from the participant's preflight value will be reported in millimeters and as percent change.","Within 24 hours before departure; within 2 hours after arrival at the study site; 24 +\u002F- 2 hours after arrival; and 48 +\u002F- 2 hours after arrival. 1 week",[14,18],{"measure":15,"description":16,"timeFrame":17},"Return of Popliteal Vein Diameter to Baseline","Proportion of participants whose mean bilateral diameter is within plus or minus 10% of their preflight value.","24 +\u002F- 2 hours and 48 +\u002F- 2 hours after arrival. 1 week",{"measure":19,"description":20,"timeFrame":21},"Incidental Venous Thrombosis or Abnormal Compressibility","Number and proportion of participants with a new noncompressible venous segment or other finding requiring diagnostic clinical evaluation. This research protocol is not designed as a definitive thrombosis screening examination unless the final duplex protocol is expanded.","From preflight baseline through 48 hours after arrival. 1week",null,{"allocation":22,"interventionModel":22,"interventionModelDescription":22,"primaryPurpose":22,"observationalModel":24,"timePerspective":25,"maskingInfo":22},"COHORT","PROSPECTIVE","Eligible international travelers will complete a standardized preflight ultrasound and three postarrival examinations before surgery or intravenous fluid therapy. Each scan will be performed after a fixed resting period using the same popliteal landmark, minimal transducer pressure, and triplicate bilateral measurements. Flight duration, class, seat characteristics, movement, fluid intake, compression stocking use, and venous risk factors will be recorded. Mixed-effects analysis will estimate the postflight diameter and cross-sectional-area trajectory and the proportion returning to within 10% of baseline by 48 hours.","Adult international medical travelers completing a commercial flight of at least 4 hours to Bogota and undergoing all ultrasound measurements before surgery.",[29],{"label":30,"type":22,"description":31,"interventionNames":32},"Postflight Repeated-Measures Cohort","All participants undergo standardized preflight and postarrival bilateral popliteal vein ultrasound without assignment to a travel intervention.",[33,34],"Other: Commercial Air Travel Exposure","Diagnostic Test: Standardized Bilateral Popliteal Vein Duplex Ultrasound",[36,41],{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":22},"OTHER","Commercial Air Travel Exposure","Participants complete a commercial flight of at least 4 hours to Bogota. Flight duration, connections, cabin class, seat characteristics, movement, fluid intake, alcohol, sedatives, and compression stocking use will be recorded. Linked arm\u002Fgroup(s): Postflight Repeated-Measures Cohort.",[30],{"type":42,"name":43,"description":44,"armGroupLabels":45,"otherNames":22},"DIAGNOSTIC_TEST","Standardized Bilateral Popliteal Vein Duplex Ultrasound","After at least 10 minutes of supine rest, the popliteal vein will be imaged at a fixed landmark with minimal probe pressure. Anteroposterior and transverse diameters, cross-sectional area, compressibility, and flow will be recorded in both legs, with three repeated measurements averaged. Linked arm\u002Fgroup(s): Postflight Repeated-Measures Cohort.",[30],[47],{"name":48,"affiliation":22,"role":49},"Hugo Aguilar, MD, plastic surgery","PRINCIPAL_INVESTIGATOR",[51],{"name":52,"role":53,"phone":54,"phoneExt":22,"email":55},"Hugo Aguilar, MD, Plastic surgeon","CONTACT","+57 301 6918526","havplasticacademy@gmail.com",[57],{"facility":58,"status":59,"city":60,"state":22,"zip":22,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"Clinica INO","RECRUITING","Bogotá","Colombia","CO",{"type":64,"coordinates":65},"Point",[66,67],-74.08175,4.60971,{"lat":67,"lon":66},[70],{"name":71,"role":53,"phone":72,"phoneExt":22,"email":55},"hugo Aguilar, MD, Plastic surgeon","+57 3016918526",{"type":74,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR","100655014","prospective-repeated-measures-study-of-popliteal-vein-diameter-during-the-first-48-hours-after-commercial-air-travel-to-bogota-for-a-plastic-surgery-intervention-100655014",false,"NCT07808411","Prospective Repeated-Measures Study of Popliteal Vein Diameter During the First 48 Hours After Commercial Air Travel to Bogota for a Plastic Surgery Intervention","Inclusion Criteria:\n\n* Age 18 to 65 years.\n* International commercial flight to Bogota with total airborne time of at least 4 hours.\n* Preflight baseline ultrasound obtained within 24 hours before departure using the standardized protocol.\n* Arrival ultrasound completed within 2 hours after reaching the study site and before surgery or intravenous fluid therapy.\n* Availability for 24-hour and 48-hour examinations.\n* Written informed consent.\n\nExclusion Criteria:\n\n* Known current deep venous thrombosis or pulmonary embolism.\n* Therapeutic anticoagulation at enrollment.\n* Major lower-extremity venous surgery, active leg infection, or condition preventing popliteal ultrasound.\n* Surgery, prolonged immobilization, or substantial intravenous fluid administration before completion of the 48-hour measurement.\n* Pregnancy.\n* Nondiagnostic baseline examination or inability to reproduce the landmark.","ALL","18 Years","65 Years",{"count":85,"type":86},100,"ESTIMATED","1 Week","OBSERVATIONAL","This prospective repeated-measures study will evaluate how long popliteal vein dilation persists after international commercial air travel to Bogota. Adult medical travelers will undergo standardized bilateral popliteal vein ultrasound within 24 hours before departure, within 2 hours after arrival, and at 24 and 48 hours after arrival, all before surgery. The primary outcome is change in mean bilateral popliteal vein diameter over time.",[91,92],"Physiologic Venous Dilation","Air Travel",[94,92,95,96,97,98],"Popliteal Vein","Medical Tourism","Venous Diameter","Duplex Ultrasound","Long-Haul Flight","2026-09-02",{"date":101,"type":102},"2026-09-08","ACTUAL",{"date":104,"type":102},"2024-01-12",{"date":106,"type":86},"2026-12-01",{"name":5,"class":6},1]