[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658808":3},{"organization":4,"outcomesModule":7,"designInfo":107,"detailedDescription":110,"studyPopulation":110,"armGroups":116,"interventions":127,"overallOfficials":136,"centralContacts":140,"locations":110,"responsibleParty":148,"collaborators":110,"id":152,"slug":153,"hasResults":154,"nctId":155,"briefTitle":156,"officialTitle":157,"acronym":110,"eligibilityCriteria":158,"healthyVolunteers":154,"sex":159,"minAge":160,"maxAge":110,"enrollmentInfo":161,"targetDuration":110,"studyType":164,"phases":165,"briefSummary":167,"conditions":168,"keywords":170,"overallStatus":175,"whyStopped":110,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":184,"locationsCount":110},{"fullName":5,"class":6},"University of Basel","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":23,"otherOutcomes":58},[9,13,17,20],{"measure":10,"description":11,"timeFrame":12},"WHO-5 Well-Being Index (World Health Organization, 1998)","Six-point Likert scale (\"0 = Never\" - \"5 = All the time\"); higher scores indicate higher levels of well-being.","Baseline; immediately before and after each intervention session; one month post-intervention; seven months post-intervention.",{"measure":14,"description":15,"timeFrame":16},"Diurnal Salivary Cortisol Slope (nmol\u002FL; Psychobiological Stress Regulation)","Salivary cortisol concentration (nmol\u002FL) from four self-collected saliva samples per day (60 minutes after awakening, 2.5 hours later, 8 hours later, and at bedtime); the diurnal slope is calculated as the rate of decline from the morning peak to the evening nadir; steeper negative slopes indicate healthier hypothalamic-pituitary-adrenal (HPA) axis regulation.","On two consecutive days pre-intervention; on the six intervention days, four samples per day.",{"measure":18,"description":19,"timeFrame":12},"Current pain Intensity (Numeric Rating Scale)","11-point Likert scale (\"0 = No Pain\" - \"10 = Strongest imaginable pain\" ); higher scores indicate higher levels of pain.",{"measure":21,"description":22,"timeFrame":12},"Relationship Assessment Scale (RAS; Hendrick, 1988)","Five-point Likert scale (\"0 = Very dissatisfied\" - \"4 = Very satisfied\"; phrasing varies by item); higher scores indicate higher relationship satisfaction.",[24,28,31,34,37,40,44,48,52,55],{"measure":25,"description":26,"timeFrame":27},"Satisfaction with Life Scale (SWLS; Diener et al., 1985)","Five-point Likert scale (\"0 = Not at all true\" - \"4 = Completely true\"); higher scores indicate higher levels of life satisfaction.","Baseline; one month post-intervention; seven months post-intervention.",{"measure":29,"description":30,"timeFrame":27},"Five Facet Mindfulness Questionnaire (FFMQ; Baer et al., 2008)","Five-point Likert scale (\"0 = Never or very rarely true\" - \"4 = Very often or almost always true\"); higher scores indicate higher levels of mindfulness.",{"measure":32,"description":33,"timeFrame":27},"Practical and Emotional Support Provision and Receipt (Shrout et al., 2006)","Six-point Likert scale (\"0 = Never\" - \"5 = Very often\"); higher scores indicate higher levels of support.",{"measure":35,"description":36,"timeFrame":27},"Endometriosis Health Profile-30 (EHP-30; Jones et al., 2001)","Six-point Likert scale (\"0 = Never\" - \"5 = Always\"); higher scores indicate higher levels of pain impact and dysfunction.",{"measure":38,"description":39,"timeFrame":27},"Endometriosis Pain and Bleeding Diary (Deal et al., 2010)","11-point Likert scale (\"0 = No pain\" - \"10 = Strongest imaginable pain\"; phrasing varies by item) and 6-point Likert scale (\"0 = Never\" - \"5 = Always\"; phrasing varies by item); higher scores indicate higher pain\u002Fbleeding severity.",{"measure":41,"description":42,"timeFrame":43},"Positive and Negative Affect Schedule (PANAS; Thompson, 2007; Watson et al., 1988)","Five-point Likert scale (\"0 = Not at all true\" - \"4 = Completely true\"); higher scores indicate higher positive or negative affect.","Baseline; immediately before and after each intervention session.",{"measure":45,"description":46,"timeFrame":47},"Generalized Anxiety Disorder Screener (GAD-7 \u002F GAD-2; Kroenke et al., 2007)","Four-point Likert scale (\"0 = Very rarely\" - \"3 = Often\"); higher scores indicate higher levels of anxiety symptoms.","Baseline (GAD-7); one month post-intervention (GAD-2); seven months post-intervention (GAD-2).",{"measure":49,"description":50,"timeFrame":51},"Patient Health Questionnaire (PHQ-9 \u002F PHQ-2; Kroenke et al., 2001)","Four-point Likert scale (\"0 = Very rarely\" - \"3 = Often\"); higher scores indicate higher levels of depressive symptoms.","Baseline (PHQ-9); one month post-intervention (PHQ-2); seven months post-intervention (PHQ-2).",{"measure":53,"description":54,"timeFrame":27},"We-Disease Questionnaire (WDQ; Vogt et al., 2024)","Four-point Likert scale (\"0 = Not applicable at all\" - \"3 = Very applicable\"); higher scores indicate stronger perception of illness as a shared dyadic challenge.",{"measure":56,"description":57,"timeFrame":27},"Female Sexual Function Index Short Form (FSFI-SF; Rosen et al., 2000)","Five- to six-point Likert scale (0-4\u002F5; phrasing varies by item); higher scores indicate better sexual function and higher satisfaction.",[59,62,65,69,73,77,80,83,86,89,92,95,98,101,104],{"measure":60,"description":61,"timeFrame":27},"Dyadic Coping Inventory (DCI; Bodenmann, 1997)","Five-point Likert scale (\"0 = Never\" - \"4 = Very often\"); higher scores indicate higher levels of dyadic support.",{"measure":63,"description":64,"timeFrame":27},"Self-Compassion Scale Short Form (SCS-SF; Raes et al., 2011)","Five-point Likert scale (\"0 = Almost never\" - \"4 = \"Almost always\"); higher scores indicate higher levels of self-compassion.",{"measure":66,"description":67,"timeFrame":68},"State Mindfulness Scale (SMF; Van Der Gucht et al., 2019)","Five-point Likert scale (\"0 = Not at all true\" - \"4 = Completely true\"); higher scores indicate higher levels of state mindfulness.","Immediately before and after each intervention session.",{"measure":70,"description":71,"timeFrame":72},"Support Evaluation (Langer et al., 2022)","Six-point Likert scale (\"0 = Not at all\" - \"5 = Very strongly\u002FCompletely\"); higher scores indicate higher levels of perceived support.","Immediately after each intervention session.",{"measure":74,"description":75,"timeFrame":76},"Acceptability of Intervention Measure, Intervention Appropriateness Measure & Feasibility of Intervention Measure (AIM, IAM, FIM; Weiner et al., 2017)","Five-point Likert scale (\"0 = Strongly disagree\" - \"4 = Strongly agree\"); higher scores indicate higher acceptability, feasibility, and perceived benefit.","Immediately after the last intervention session.",{"measure":78,"description":79,"timeFrame":27},"Partnerschaftsfragebogen (Conflict Behavior Subscale; Hahlweg, 1996)","Six-point Likert scale (\"0 = Never\" - \"5 = Always\"); higher scores indicate higher frequency of negative conflict behavior.",{"measure":81,"description":82,"timeFrame":27},"Global Measure of Sexual Satisfaction (GMSEX; Lawrance & Byers, 1995)","Seven-point bipolar Likert scale (0-6; phrasing varies by item); higher scores indicate higher sexual satisfaction.",{"measure":84,"description":85,"timeFrame":27},"Inclusion of Other in the Self Scale (IOS; Aron et al., 1992)","Seven-point pictorial scale; higher scores indicate greater closeness and overlap with partner.",{"measure":87,"description":88,"timeFrame":27},"Relationship Commitment (Rusbult et al., 1998)","Seven-point Likert scale (\"0 = Do not agree at all \" - \"6 = Agree completely\"); higher scores indicate higher levels of relationship commitment.",{"measure":90,"description":91,"timeFrame":76},"Glasgow Benefit Inventory (GBI; Robinson et al., 1996)","Five-point Likert scale (0-4; phrasing varies by item); higher scores indicate higher levels of perceived benefit.",{"measure":93,"description":94,"timeFrame":27},"Sexual Desire to Partner (Spector et al., 1996)","Five-point Likert scale (\"0 = Not at all\" - \"4 = Very\"); higher scores indicate higher sexual desire toward partner.",{"measure":96,"description":97,"timeFrame":68},"Intimacy (Langer et al., 2022)","Six-point Likert scale (\"0 = Not at all\" - \"5 = Very strongly\u002FCompletely\"); higher scores indicate higher levels of intimacy.",{"measure":99,"description":100,"timeFrame":68},"Perceived and Enacted Partner Responsiveness (Laurenceau et al., 2005)","Five-point Likert scale (\"0 = Little\" - \"4 = Very\"); higher scores indicate higher perceived or enacted partner responsiveness.",{"measure":102,"description":103,"timeFrame":27},"Exchange of Physical Affection (Debrot et al., 2013; Sorokowska et al., 2023; modified)","Frequency categories and five\u002Fsix-point Likert scale (0-4\u002F5; phrasing varies by item); higher scores indicate higher frequency of and satisfaction with physical affection.",{"measure":105,"description":106,"timeFrame":27},"Sexual Communal Strength Scale (SCS; Muise et al., 2013)","Five-point Likert scale (\"0 = Not at all\" - \"4 = Very\"); higher scores indicate higher sexual communal strength.",{"allocation":108,"interventionModel":109,"interventionModelDescription":110,"primaryPurpose":111,"observationalModel":110,"timePerspective":110,"maskingInfo":112},"RANDOMIZED","PARALLEL",null,"TREATMENT",{"masking":113,"maskingDescription":110,"whoMasked":114},"SINGLE",[115],"PARTICIPANT",[117,122],{"label":118,"type":119,"description":110,"interventionNames":120},"Control","ACTIVE_COMPARATOR",[121],"Behavioral: Control",{"label":123,"type":124,"description":110,"interventionNames":125},"EMPOWER-Intervention","EXPERIMENTAL",[126],"Behavioral: EMPOWER",[128,133],{"type":129,"name":130,"description":131,"armGroupLabels":132,"otherNames":110},"BEHAVIORAL","EMPOWER","The EMPOWER intervention consists of six 30-60 minute couple sessions (3x per week over two weeks), conducted at home via guided audio. Each session combines a structured mindfulness exercise (progressing difficulty) with a mutual partner support conversation (structured speaker-listener format, progressing difficulty).",[123],{"type":129,"name":118,"description":134,"armGroupLabels":135,"otherNames":110},"The active control condition consists of six sessions of similar length, comprising psychoeducation about endometriosis and chronic pain, unguided relaxation to music, and less structured couple conversations without the partner support component.",[118],[137],{"name":138,"affiliation":5,"role":139},"Maximiliane Uhlich, PhD","PRINCIPAL_INVESTIGATOR",[141,145],{"name":138,"role":142,"phone":143,"phoneExt":110,"email":144},"CONTACT","+41 61 207 82 85","maximiliane.uhlich@unibas.ch",{"name":146,"role":142,"phone":110,"phoneExt":110,"email":147},"Simone Wyss, MSc","si.wyss@unibas.ch",{"type":149,"investigatorFullName":150,"investigatorTitle":151,"investigatorAffiliation":5,"oldNameTitle":110,"oldOrganization":110},"SPONSOR_INVESTIGATOR","Maximiliane Uhlich","Principal Investigator","100658808","protective-factors-for-well-being-in-endometriosis-patients-100658808",false,"NCT07854925","Protective Factors for Well-being in Endometriosis Patients","Resilience Through Connection: Protective Factors for Well-bein in Endometriosis Patients","Inclusion Criteria:\n\n* clinically confirmed endometriosis diagnosis\n* subjective impact on well-being\n* currently in a relationship\n* both partners willing to participate\n* fluency in German\n* residency in German-speaking Switzerland\n* ability to provide informed consent\n\nExclusion Criteria:\n\n* self-diagnosed endometriosis\n* asymptomatic endometriosis\n* single individuals\n* only one partner willing to participate\n* no access to a mobile device\n* pregnancy","FEMALE","18 Years",{"count":162,"type":163},200,"ESTIMATED","INTERVENTIONAL",[166],"NA","Endometriosis is a common chronic condition in which tissue resembling the lining of the uterus grows outside the uterus. It affects up to 10% of all women, causes severe pain, and places a significant burden on those affected. Current treatments often provide insufficient relief, and the impact of psychosocial factors on the well-being of those affected has received little research attention to date.\n\nWith this study, the investigators aim to improve the well-being of women with endometriosis. To this end, the investigators have developed the EMPOWER intervention, a couple-based program designed to enhance well-being.\n\nThe intervention is intended to alleviate pain, improve well-being, and help both partners cope better with the condition. The findings will be published in a free self-help manual intended to benefit those affected worldwide.",[169],"Endometriosis",[169,171,172,173,174],"Women's health","Mindfulness","Partner Support","Well-being","NOT_YET_RECRUITING","2026-09-28",{"date":178,"type":179},"2026-10-02","ACTUAL",{"date":181,"type":163},"2026-10",{"date":183,"type":163},"2029-10",{"name":150,"class":6}]