[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648710":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":36,"centralContacts":41,"locations":51,"responsibleParty":118,"collaborators":121,"id":128,"slug":129,"hasResults":130,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":134,"eligibilityCriteria":135,"healthyVolunteers":136,"sex":137,"minAge":138,"maxAge":10,"enrollmentInfo":139,"targetDuration":10,"studyType":142,"phases":10,"briefSummary":143,"conditions":144,"keywords":146,"overallStatus":87,"whyStopped":10,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":159},{"fullName":5,"class":6},"Beijing Tsinghua Chang Gung Hospital","OTHER",[8,14,18,22],{"label":9,"type":10,"description":11,"interventionNames":12},"Retrospective PE Cases",null,"Patients aged 18 years or older with acute pulmonary embolism confirmed by CT pulmonary angiography, with completed pulsatile electrical impedance tomography examination and available clinical data in the retrospective phase.",[13],"Diagnostic Test: Pulsatile Electrical Impedance Tomography",{"label":15,"type":10,"description":16,"interventionNames":17},"Retrospective Healthy Controls","Adults in the retrospective phase without evidence of lower-extremity venous thrombosis, with normal D-dimer levels, simplified Wells score ≤1, and no pulmonary embolism-related symptoms or history.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Prospective PE Patients","Patients aged 18 years or older newly diagnosed with pulmonary embolism by CT pulmonary angiography or CT pulmonary angiography plus CT venography, who voluntarily participate and provide written informed consent.",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Prospective Non-PE Controls","Patients aged 18 years or older with suspected acute pulmonary embolism who undergo CT pulmonary angiography or CT pulmonary angiography plus CT venography, but in whom pulmonary embolism is not confirmed. These participants voluntarily participate and provide written informed consent in the prospective phase.",[13],[27],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DIAGNOSTIC_TEST","Pulsatile Electrical Impedance Tomography","Pulsatile electrical impedance tomography will be used to obtain EIT-derived parameters, including the ventilation-perfusion matching index, dead-space ventilation index, and intrapulmonary shunt index. These parameters will be compared with CT pulmonary angiography and clinical indicators to evaluate the diagnostic performance, risk stratification value, and dynamic monitoring value of EIT in acute pulmonary embolism. This diagnostic assessment does not assign participants to treatment and does not alter routine clinical management.",[23,19,15,9],[33,34,35],"Pulsatile EIT","Electrical Impedance Tomography","EIT",[37],{"name":38,"affiliation":39,"role":40},"weiwei Wu, MD","Beijing Tsinghua Changgeng Hospital","PRINCIPAL_INVESTIGATOR",[42,47],{"name":43,"role":44,"phone":45,"phoneExt":10,"email":46},"jiazheng Li, MD","CONTACT","+86-18810886832","ljzs00357@btch.edu.cn",{"name":48,"role":44,"phone":49,"phoneExt":10,"email":50},"weiwei wu, MD","+86-13426397036","weiwei.wu@btch.edu.cn",[52,74,85,103],{"facility":53,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"Peking Union Medical College Hospital","NOT_YET_RECRUITING","Beijing","Beijing Municipality","100730","China","CN",{"type":61,"coordinates":62},"Point",[63,64],116.39723,39.9075,{"lat":64,"lon":63},[67,71],{"name":68,"role":44,"phone":69,"phoneExt":10,"email":70},"YUN LONG, MD","+86-10-69155707","2801634102@qq.com",{"name":72,"role":73,"phone":10,"phoneExt":10,"email":10},"yun long, MD","SUB_INVESTIGATOR",{"facility":75,"status":54,"city":55,"state":56,"zip":76,"country":58,"countryCode":59,"cosmosGeoPoint":77,"geoPoint":79,"contacts":80},"Beijing Tsinghua Changgung Hospital","102218",{"type":61,"coordinates":78},[63,64],{"lat":64,"lon":63},[81,82,84],{"name":48,"role":44,"phone":49,"phoneExt":10,"email":50},{"name":83,"role":44,"phone":45,"phoneExt":10,"email":46},"jiazheng LI, MD",{"name":48,"role":40,"phone":10,"phoneExt":10,"email":10},{"facility":86,"status":87,"city":88,"state":89,"zip":90,"country":58,"countryCode":59,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Chenzhou First People's Hospital","RECRUITING","Chenzhou","Hunan","423000",{"type":61,"coordinates":92},[93,94],113.03333,25.8,{"lat":94,"lon":93},[97,101,102],{"name":98,"role":44,"phone":99,"phoneExt":10,"email":100},"shaofei xu, MD","+86-13617356697","742025632@qq.com",{"name":10,"role":44,"phone":10,"phoneExt":10,"email":100},{"name":98,"role":73,"phone":10,"phoneExt":10,"email":10},{"facility":104,"status":54,"city":105,"state":89,"zip":106,"country":58,"countryCode":59,"cosmosGeoPoint":107,"geoPoint":111,"contacts":112},"Loudi Central Hospital","Loudi","417000",{"type":61,"coordinates":108},[109,110],111.99444,27.73444,{"lat":110,"lon":109},[113,117],{"name":114,"role":44,"phone":115,"phoneExt":10,"email":116},"junbiao huang, MD","+8618873820320","695997696@qq.com",{"name":114,"role":73,"phone":10,"phoneExt":10,"email":10},{"type":40,"investigatorFullName":119,"investigatorTitle":120,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Weiwei Wu","Vice President and Chair, Department of Vascular Surgery; Professor and Chief Physician",[122,123,125,127],{"name":53,"class":6},{"name":124,"class":6},"Tsinghua University",{"name":126,"class":6},"First People's Hospital of Chenzhou",{"name":104,"class":6},"100648710","pulsatile-electrical-impedance-tomography-for-diagnosis-and-monitoring-of-acute-pulmonary-embolism-100648710",false,"NCT07724197","Pulsatile Electrical Impedance Tomography for Diagnosis and Monitoring of Acute Pulmonary Embolism","A Multicenter Retrospective and Prospective Diagnostic Observational Study of Pulsatile Electrical Impedance Tomography for Diagnosis, Risk Stratification, and Dynamic Monitoring of Acute Pulmonary Embolism","EIT-PE","Inclusion Criteria:\n\n* Adults aged 18 years or older. For retrospective PE cases: patients with acute pulmonary embolism confirmed by CT pulmonary angiography, with completed pulsatile electrical impedance tomography examination, adequate image data, and available clinical information.\n\nFor retrospective healthy controls: adults without evidence of lower-extremity venous thrombosis, with normal D-dimer levels, simplified Wells score ≤1, and no pulmonary embolism-related symptoms or history.\n\nFor prospective PE patients: patients newly diagnosed with pulmonary embolism by CT pulmonary angiography or CT pulmonary angiography plus CT venography, with body mass index less than 50 kg\u002Fm², who voluntarily participate and provide written informed consent.\n\nFor prospective non-PE controls: patients with suspected acute pulmonary embolism who undergo CT pulmonary angiography or CT pulmonary angiography plus CT venography, but in whom pulmonary embolism is not confirmed, who voluntarily participate and provide written informed consent.\n\nExclusion Criteria:\n\n* Previous diagnosis of chronic pulmonary embolism or idiopathic pulmonary arterial hypertension.\n\nAcute exacerbation of chronic obstructive pulmonary disease, acute heart failure, acute myocardial infarction, or other severe cardiopulmonary diseases that may interfere with study assessment.\n\nPregnancy or lactation. Thoracic deformity. Contraindications to EIT examination, including automatic implantable cardioverter defibrillator, chest wounds limiting electrode belt placement, implanted pumps, or other conditions unsuitable for EIT electrode belt placement.\n\nParticipation in another clinical trial during the same period, for prospective participants.\n\nUnstable vital signs requiring emergency rescue, leaving no time to complete EIT examination, for prospective participants.\n\nAny other condition considered unsuitable for participation by the investigators.",true,"ALL","18 Years",{"count":140,"type":141},275,"ESTIMATED","OBSERVATIONAL","This multicenter observational diagnostic study aims to evaluate pulsatile electrical impedance tomography (EIT) for the diagnosis and monitoring of acute pulmonary embolism. The study includes a retrospective phase and a prospective phase. EIT-derived ventilation-perfusion matching index, dead-space ventilation index, and intrapulmonary shunt index will be compared with CT pulmonary angiography and relevant clinical indicators. The study is designed to assess whether EIT can provide a noninvasive, bedside, radiation-free method for pulmonary embolism diagnosis, risk stratification, and dynamic treatment monitoring.",[145],"Pulmonary Embolism Acute",[147,29,148,149],"Acute Pulmonary Embolism","Ventilation-Perfusion","Risk Stratification","2026-08-02",{"date":152,"type":153},"2026-08-04","ACTUAL",{"date":155,"type":153},"2026-01-02",{"date":157,"type":141},"2028-12-30",{"name":5,"class":6},4]