[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648160":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":54,"collaborators":26,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":26,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":26,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Kanuni Sultan Suleyman Training and Research Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Quadro-Iliac Plane Block Group","EXPERIMENTAL","Participants assigned to this group will receive an ultrasound-guided unilateral quadroiliac plane block on the surgical side while under general anesthesia. The block will be performed using 40 mL of 0.25% bupivacaine. All participants will receive the same standardized multimodal analgesic regimen and postoperative intravenous patient-controlled analgesia with tramadol.",[13],"Procedure: Ultrasound-Guided Quadroiliac Plane Block",{"label":15,"type":16,"description":17,"interventionNames":18},"Surgical Wound Infiltration Group","ACTIVE_COMPARATOR","Participants assigned to this group will receive surgical wound infiltration at the end of surgery. A total of 10 mL of 0.25% bupivacaine will be infiltrated into the subcutaneous tissues along the surgical incision. All participants will receive the same standardized multimodal analgesic regimen and postoperative intravenous patient-controlled analgesia with tramadol.",[19],"Procedure: Surgical Wound Infiltration With Bupivacaine",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Ultrasound-Guided Quadroiliac Plane Block","With the participant in the lateral decubitus position, a low-frequency curvilinear ultrasound transducer will be positioned immediately above the posterior superior iliac spine and oriented parallel to the vertebral column. The quadratus lumborum muscle, its attachment to the iliac crest, and the erector spinae muscle will be identified. A 22-gauge, 80-mm echogenic needle will be advanced using an in-plane approach into the fascial plane between the quadratus lumborum and erector spinae muscles. After confirmation of the target plane by hydrodissection and negative aspiration, 40 mL of 0.25% bupivacaine will be administered on the surgical side.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Surgical Wound Infiltration With Bupivacaine","Following completion of surgical closure, a total of 10 mL of 0.25% bupivacaine will be infiltrated evenly into the subcutaneous tissues along the surgical incision. The infiltration will be performed using a standardized technique before the participant emerges from general anesthesia.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Engin ihsan Turan, principal investigator","CONTACT","+905382431114","enginihsan@hotmail.com",[38],{"facility":39,"status":40,"city":41,"state":41,"zip":42,"country":43,"countryCode":26,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital","RECRUITING","Istanbul","34303","Turkey (Türkiye)",{"type":45,"coordinates":46},"Point",[47,48],28.94966,41.01384,{"lat":48,"lon":47},[51],{"name":52,"role":34,"phone":53,"phoneExt":26,"email":36},"Engin ihsan Turan","05382431114",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Engin Ihsan Turan","principal investigator","100648160","quadroiliac-plane-block-for-analgesia-after-renal-transplantation-100648160",false,"NCT07716566","Quadroiliac Plane Block for Analgesia After Renal Transplantation","Analgesic Efficacy of Ultrasound-Guided Quadroiliac Plane Block Versus Surgical Wound Infiltration in Patients Undergoing Renal Transplantation: A Prospective, Randomized, Double-Blind, Controlled Clinical Trial","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* American Society of Anesthesiologists physical status I-III\n* Scheduled to undergo renal transplantation surgery\n* Ability to understand the study procedures and postoperative assessments\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Known allergy to bupivacaine or other amide-type local anesthetics\n* Infection at the planned injection site\n* Coagulopathy or anticoagulant therapy associated with an unacceptable bleeding risk for regional anesthesia\n* Sepsis\n* Severe spinal deformity or anatomical abnormality preventing performance of the quadroiliac plane block\n* Inability to cooperate or communicate reliably\n* Cognitive impairment or intellectual disability preventing informed consent or reliable outcome assessment\n* Altered level of consciousness\n* Breastfeeding\n* Refusal to participate","FEMALE","18 Years","80 Years",{"count":69,"type":70},60,"ESTIMATED","INTERVENTIONAL",[73],"NA","Renal transplantation is a major abdominal surgical procedure that may cause moderate to severe postoperative pain. Opioids are commonly used as part of multimodal analgesia; however, opioid-related adverse effects such as sedation, respiratory depression, nausea, vomiting, and constipation may delay recovery and mobilization.\n\nThe quadroiliac plane block is an ultrasound-guided interfascial plane block performed near the attachment of the quadratus lumborum muscle to the iliac crest. The technique may provide analgesia over a broad lower abdominal area and may reduce postoperative opioid requirements.\n\nThis prospective, randomized, double-blind, controlled clinical trial will compare an ultrasound-guided unilateral quadroiliac plane block with surgical wound infiltration in adult patients undergoing renal transplantation. Participants will be randomly assigned to receive either a quadroiliac plane block with 40 mL of 0.25% bupivacaine or surgical wound infiltration with 10 mL of 0.25% bupivacaine.\n\nAll participants will receive standardized multimodal analgesia and intravenous patient-controlled analgesia with tramadol. The primary objective is to compare cumulative tramadol consumption during the first 24 hours after surgery. Postoperative pain scores, dermatomal sensory distribution, motor block, nausea, vomiting, sedation, and quality of recovery will also be evaluated.",[76],"Postoperative Pain","2026-07-29",{"date":79,"type":80},"2026-07-30","ACTUAL",{"date":82,"type":70},"2026-07-20",{"date":84,"type":70},"2027-07-21",{"name":5,"class":6},1]