[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655270":3},{"organization":4,"outcomesModule":7,"designInfo":23,"detailedDescription":32,"studyPopulation":22,"armGroups":33,"interventions":47,"overallOfficials":63,"centralContacts":67,"locations":73,"responsibleParty":90,"collaborators":22,"id":92,"slug":93,"hasResults":94,"nctId":95,"briefTitle":96,"officialTitle":96,"acronym":22,"eligibilityCriteria":97,"healthyVolunteers":94,"sex":98,"minAge":99,"maxAge":100,"enrollmentInfo":101,"targetDuration":22,"studyType":104,"phases":105,"briefSummary":107,"conditions":108,"keywords":111,"overallStatus":76,"whyStopped":22,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":125},{"fullName":5,"class":6},"Research Inc","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":22},[9],{"measure":10,"description":11,"timeFrame":12},"Difference in Change in Mean Bilateral Popliteal Vein Diameter","Between-group difference in baseline-to-arrival change in the mean of triplicate anteroposterior diameter measurements from both legs, reported in millimeters and percent change.","Within 24 hours before departure and within 2 hours after arrival at the study site. 2 days",[14,18],{"measure":15,"description":16,"timeFrame":17},"Incidence of Stocking-Related Adverse Effects","Proportion with skin injury, numbness, clinically significant pain, intolerance, or early removal attributed to the stocking.","From stocking application through 24 hours after arrival. 5 days",{"measure":19,"description":20,"timeFrame":21},"Incidental Venous Thrombosis or Abnormal Compressibility","Number and proportion with an ultrasound abnormality requiring urgent clinical assessment.","From preflight baseline through 48 hours after arrival - 1 week",null,{"allocation":24,"interventionModel":25,"interventionModelDescription":22,"primaryPurpose":26,"observationalModel":22,"timePerspective":22,"maskingInfo":27},"RANDOMIZED","PARALLEL","PREVENTION",{"masking":28,"maskingDescription":22,"whoMasked":29},"DOUBLE",[30,31],"CARE_PROVIDER","OUTCOMES_ASSESSOR","Eligible economy-class travelers will be randomized before departure. The intervention group will wear properly fitted knee-high graduated compression stockings from approximately 1 hour before boarding through the arrival ultrasound; the control group will not use lower-limb compression. A masked ultrasound assessor will obtain standardized bilateral diameter and cross-sectional-area measurements before flight and at arrival, 24 hours, and 48 hours. Adherence, movement, hydration, symptoms, and skin effects will be recorded. Intention-to-treat mixed models will estimate immediate and persistent treatment effects.",[34,42],{"label":35,"type":36,"description":37,"interventionNames":38},"Moderate Compression Stockings","EXPERIMENTAL","Participants wear properly fitted knee-high graduated compression stockings during the qualifying flight, beginning approximately 1 hour before boarding and removing them after the arrival ultrasound. all patients got enoxaparin to prevent blood clots",[39,40,41],"Drug: Enoxaparine","Device: Knee-High Graduated Compression Stockings","Diagnostic Test: Standardized Bilateral Popliteal Vein Ultrasound",{"label":43,"type":44,"description":45,"interventionNames":46},"No Compression Stockings","ACTIVE_COMPARATOR","Participants do not wear compression stockings or another lower-limb compression device during the qualifying flight. All patients got enoxaparin to prevent blood clots",[39,41],[48,53,58],{"type":49,"name":50,"description":51,"armGroupLabels":52,"otherNames":22},"DRUG","Enoxaparine","All patients got enoxaparin to prevent blood clots",[35,43],{"type":54,"name":55,"description":56,"armGroupLabels":57,"otherNames":22},"DEVICE","Knee-High Graduated Compression Stockings","PROPOSED pressure class: 20-30 mmHg at the ankle, appropriately sized according to calf and ankle circumference, worn from approximately 1 hour before boarding until completion of the arrival ultrasound. The final product, pressure class, fitting method, and wear instructions must be confirmed. Linked arm\u002Fgroup(s): Moderate Compression Stockings.",[35],{"type":59,"name":60,"description":61,"armGroupLabels":62,"otherNames":22},"DIAGNOSTIC_TEST","Standardized Bilateral Popliteal Vein Ultrasound","Triplicate bilateral diameter and cross-sectional-area measurements after a standardized rest period, with compressibility and flow assessment by an assessor masked to allocation. Linked arm\u002Fgroup(s): Moderate Compression Stockings, No Compression Stockings.",[35,43],[64],{"name":65,"affiliation":22,"role":66},"Hugo Aguilar","PRINCIPAL_INVESTIGATOR",[68],{"name":69,"role":70,"phone":71,"phoneExt":22,"email":72},"Hugo Aguilar, MD, Plastic surgeon","CONTACT","+57 301 6918526","havplasticacademy@gmail.com",[74],{"facility":75,"status":76,"city":77,"state":22,"zip":22,"country":78,"countryCode":79,"cosmosGeoPoint":80,"geoPoint":85,"contacts":86},"Clinica INO","RECRUITING","Bogotá","Colombia","CO",{"type":81,"coordinates":82},"Point",[83,84],-74.08175,4.60971,{"lat":84,"lon":83},[87],{"name":88,"role":70,"phone":89,"phoneExt":22,"email":72},"hugo Aguilar, MD, Plastic surgeon","+57 3016918526",{"type":91,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR","100655270","randomized-assessor-masked-trial-of-moderate-graduated-compression-stockings-for-popliteal-vein-dilation-during-long-haul-economy-class-air-travel-after-aesthetic-surgery-100655270",false,"NCT07810192","Randomized Assessor-Masked Trial of Moderate Graduated Compression Stockings for Popliteal Vein Dilation During Long-Haul Economy-Class Air Travel After Aesthetic Surgery","Inclusion Criteria:\n\n* Age 18 to 65 years.\n* Economy-class commercial itinerary to Bogota with at least 4 hours of total airborne time.\n* No clinical indication that mandates or prohibits compression stockings.\n* Ability to obtain the assigned stocking before boarding and wear it as instructed.\n* Standardized preflight and postarrival ultrasounds completed before surgery.\n* Written informed consent.\n\nExclusion Criteria:\n\n* Current deep venous thrombosis, therapeutic anticoagulation, or severe peripheral arterial disease.\n* Significant lower-limb skin disease, ulceration, neuropathy, or deformity preventing safe stocking use.\n* Pregnancy.\n* Planned use of another compression device during the flight.\n* Surgery or major intravenous fluid therapy before completion of the 48-hour examination.\n* Inability to complete preflight ultrasound or follow assigned treatment.","ALL","18 Years","65 Years",{"count":102,"type":103},160,"ESTIMATED","INTERVENTIONAL",[106],"NA","This randomized assessor-masked trial will evaluate whether knee-high moderate graduated compression stockings reduce popliteal vein dilation during long-haul economy-class air travel to Bogota. Participants will be assigned to stockings or no stockings and will undergo bilateral ultrasound before flight, within 2 hours after arrival, and at 24 and 48 hours. The primary outcome is the between-group difference in change in mean bilateral popliteal vein diameter from preflight baseline to arrival.",[109,110],"Physiologic Venous Dilation","Air Travel",[112,110,113,114,115],"Compression Stockings","Popliteal Vein","Duplex Ultrasound","Medical Tourism","2026-09-02",{"date":118,"type":119},"2026-09-09","ACTUAL",{"date":121,"type":119},"2024-01-01",{"date":123,"type":103},"2026-12-01",{"name":5,"class":6},1]