[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648963":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":69,"collaborators":71,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":79,"sex":85,"minAge":86,"maxAge":25,"enrollmentInfo":87,"targetDuration":25,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":98,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"Regional Specialist Hospital in Wroclaw","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"RESET Intervention","EXPERIMENTAL","Participants receive the comprehensive RESET perioperative care pathway, including individualized multidisciplinary prehabilitation, structured perioperative management, enhanced recovery principles, coordinated discharge planning, transitional care, and follow-up using the RESET digital platform. The intervention is tailored to individual patient needs while following standardized study procedures. Both oncology and elderly (non-oncology) participants may be allocated to this arm.",[13],"Other: RESET multimodal perioperative care pathway",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Perioperative Care","ACTIVE_COMPARATOR","Participants receive standard perioperative care according to routine institutional practice without the coordinated RESET programme. Standard care may include selected supportive interventions if clinically indicated but does not include the structured multidisciplinary RESET pathway. Both oncology and elderly (non-oncology) participants may be allocated to this arm.",[19],"Other: Standard perioperative care",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"RESET multimodal perioperative care pathway","RESET is a standardized, individualized, multidisciplinary perioperative care pathway delivered from approximately 21±7 days before surgery through 30-day follow-up. It includes: (1) preoperative assessment and personalized prehabilitation addressing nutrition, physical activity, psychological support, and medication optimization; (2) care coordination and communication with the prehabilitation team, supported by the RESET mobile application; (3) reassessment on hospital admission and coordinated perioperative planning; (4) enhanced recovery during hospitalization, including early mobilization, nutritional support, pain management, the SAFER Patient Flow Bundle, and Red-to-Green review; and (5) individualized discharge planning and transitional care. Components are tailored to the participant's clinical status, functional capacity, nutritional and psychological needs, comorbidities, and planned surgery.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standard perioperative care","Participants receive standard perioperative care according to routine practice at the participating hospital. This includes usual surgical and anesthetic qualification, preoperative tests and consultations when clinically indicated, routine inpatient surgical and postoperative care, discharge instructions, and standard follow-up. Participants do not receive the coordinated multidisciplinary RESET pathway or individualized RESET recommendations. Protocol-defined assessments and activity monitoring are performed in both study arms for research purposes and are not components of the comparator intervention.",[15],[31],{"name":32,"affiliation":5,"role":33},"Małgorzata Wierzbicka, Professor","PRINCIPAL_INVESTIGATOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Natalia Jędruchniewicz, PhD","CONTACT","+48713270538","natalia.jedruchniewicz@wssk.wroc.pl",[41,60],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"4th Military Clinical Hospital in Wroclaw","RECRUITING","Wroclaw","Lower Silesian Voivodeship","50-981","Poland","PL",{"type":50,"coordinates":51},"Point",[52,53],17.03006,51.10286,{"lat":53,"lon":52},[56],{"name":57,"role":37,"phone":58,"phoneExt":25,"email":59},"Anna Skotny, PhD","(+48) 71 727 41 46","cwbk@4wsk.pl",{"facility":61,"status":43,"city":44,"state":45,"zip":62,"country":47,"countryCode":48,"cosmosGeoPoint":63,"geoPoint":65,"contacts":66},"Regional Specialist Hospital in Wrocław","51-124",{"type":50,"coordinates":64},[52,53],{"lat":53,"lon":52},[67,68],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},{"name":32,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":70,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[72,75],{"name":73,"class":74},"Łukasiewicz Research Network - PORT Polish Center for Technology Development","UNKNOWN",{"name":76,"class":6},"4th Military Clinical Hospital with Polyclinic, Poland","100648963","ready-for-safe-cancer-treatment-reset-a-comprehensive-perioperative-program-for-surgical-oncology-100648963",false,"NCT07727876","Ready for Safe Cancer Treatment (RESET): A Comprehensive Perioperative Program for Surgical Oncology","Comprehensive Tool to Improve the Quality and Optimize Hospitalization of Oncological Surgery Patients Implemented for Timely, Safe Discharge From Hospital - Ready for Safe Cancer Treatment RESET, Consisting of a Standardized Sequence of Processes -From Prehabilitation, Therapeutic Team\u002FPatient\u002FFamily Advanced Communication, Early Rehabilitation Protocol, Followed by Individual Transitional Care Program, Dedicated to Oncology Network Hospitals","RESET","ONCOLOGY GROUP\n\nInclusion Criteria:\n\n* Age ≥ 18 years\n* Qualification for admission to surgical departments with an ICD10 diagnosis for radical cancer surgery\n* Preliminary qualification for one of the procedures listed in Section II.B.23\n* Informed consent to participate in the study\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Qualification for admission to surgical departments with an ICD10 diagnosis for diagnostic procedures to identify cancer\n* Pregnancy or breastfeeding\n\nNON-ONCOLOGY GROUP\n\nInclusion Criteria:\n\n* Informed consent to participate in the study\n* Age ≥ 70 years\n* All consecutive patients referred for planned non-oncological surgical procedures, not solely diagnostic, performed under general anesthesia\n\nExclusion Criteria:\n\n\\- Diagnosis of cancer","ALL","18 Years",{"count":88,"type":89},12800,"ESTIMATED","INTERVENTIONAL",[92],"NA","The goal of this randomized controlled clinical trial is to evaluate whether the Ready for Safe Cancer Treatment (RESET) program improves perioperative care and supports safe hospital discharge in two surgical populations: adult patients undergoing planned oncological surgery and patients aged 70 years or older undergoing planned non-oncological surgery under general anesthesia.\n\nRESET is a comprehensive, multidisciplinary care pathway that combines prehabilitation, standardized perioperative care, enhanced recovery, and individualized transitional care after discharge.\n\nThe main questions it aims to answer are:\n\nDoes the RESET program reduce postoperative complications, prolonged hospitalizations, and unplanned rehospitalizations after oncological and non-oncological surgery?\n\nDoes the RESET program improve patients' overall health status, physical function, quality of life, perioperative safety, and recovery?\n\nDoes implementation of RESET improve the organization and efficiency of hospital care while reducing healthcare resource utilization and costs?\n\nResearchers will compare patients receiving the RESET program with patients receiving standard perioperative care to determine whether the comprehensive intervention leads to improved clinical, organizational, and patient-reported outcomes.\n\nParticipants assigned to the RESET intervention will:\n\nundergo a comprehensive multidisciplinary prehabilitation assessment performed by a physician, physiotherapist, dietitian, psychologist, clinical pharmacist, nurse, and study coordinator;\n\nreceive an individualized prehabilitation program that may include physical exercise, nutritional support, psychological support, medication optimization, and patient education before surgery;\n\nuse a dedicated RESET mobile application to communicate with the multidisciplinary prehabilitation team, ask questions, receive individualized recommendations and information, follow the schedule of visits and planned activities, and support adherence to the intervention;\n\nundergo reassessment of their health status, needs, and implementation of recommendations on the day of hospital admission, allowing barriers to be identified and the perioperative care plan to be optimized;\n\nreceive standardized in-hospital perioperative care incorporating Enhanced Recovery After Surgery principles, the SAFER Patient Flow Bundle, the Red2Green methodology, medication review by a clinical pharmacist, and coordinated multidisciplinary care;\n\nreceive an individualized transitional care plan after discharge, including follow-up support and monitoring for complications and rehospitalization.\n\nParticipants in the control group will receive standard perioperative care according to routine clinical practice at the participating hospitals.\n\nThe study will evaluate clinical outcomes, including postoperative complications, prolonged hospitalization, rehospitalization, recovery, overall health status, physical function, and quality of life. It will also evaluate patient satisfaction, adherence to the RESET pathway, organizational effectiveness, and costs associated with implementation of RESET.\n\nThe results are expected to support the development of an evidence-based and scalable perioperative care model that can be used in oncological surgery and in older patients undergoing major non-oncological surgery.",[95,96,97],"Neoplasms","Frailty","Surgical Procedures, Operative",[99,100,101,102,103,104,105,106,107,108,109,110,111,112,113],"prehabilitation","perioperative care","surgical oncology","enhanced recovery after surgery","transitional care","hospital discharge","multidisciplinary care","postoperative complications","rehospitalization","prolonged hospitalization","patient flow","frailty","geriatric surgery","cancer surgery","supportive care","2026-07-24",{"date":116,"type":117},"2026-07-27","ACTUAL",{"date":119,"type":117},"2026-02-16",{"date":121,"type":89},"2031-07-31",{"name":5,"class":6},2]