[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646739":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":36,"centralContacts":44,"locations":25,"responsibleParty":51,"collaborators":25,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":25,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":25,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":74,"whyStopped":25,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":25},{"fullName":5,"class":6},"Zagazig University","OTHER_GOV",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Serratus-intercostal plane block","ACTIVE_COMPARATOR","The patients will receive an ultrasound-guided serratus-intercostal plane block after induction of general anaesthesia and before surgical incision.",[13,14],"Procedure: Serratus-intercostal plane block","Drug: Dexmedetomidine Injection",{"label":16,"type":10,"description":17,"interventionNames":18},"Erector spinae plane block","The patients will receive an ultrasound-guided erector spinae plane block after induction of general anaesthesia and before surgical incision.",[19,14],"Procedure: Erector spinae plane block",[21,26,29],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","The patients will receive an ultrasound-guided serratus-intercostal plane block after induction of anaesthesia, using 0.25% bupivacaine and 1 μg\u002Fkg dexmedetomidine.",[9],null,{"type":22,"name":16,"description":27,"armGroupLabels":28,"otherNames":25},"The patients will receive an ultrasound-guided erector spinae plane block after induction of anaesthesia, using 0.25% bupivacaine and 1 μg\u002Fkg dexmedetomidine.",[16],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"DRUG","Dexmedetomidine Injection","The local anaesthetic mixture will include 0.25% bupivacaine plus 1 μg\u002Fkg dexmedetomidine.",[16,9],[35],"Precedex",[37,41],{"name":38,"affiliation":39,"role":40},"Nahla Mohamed Amin, MD","Department of Anesthesia, Intensive Care & Pain Management, Zagazig University","STUDY_DIRECTOR",{"name":42,"affiliation":39,"role":43},"Samia Mohamed Masoud, MD","STUDY_CHAIR",[45],{"name":46,"role":47,"phone":48,"phoneExt":49,"email":50},"Amal Hossieny Gamil Mohamed, MSc","CONTACT","01001882257","+20","Amaalhossienyy@gmail.com",{"type":52,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100646739","regional-block-for-post-mastectomy-analgesia-100646739",false,"NCT07683416","Regional Block for Post-mastectomy Analgesia","Dexmedetomidine as an Adjuvant to Bupivacaine for Serratus-Intercostal Versus Erector-Spinae Plane Block to Relieve Post-Mastectomy Pain","Inclusion Criteria:\n\n* Unilateral mastectomy operations.\n* Body mass index less than 35 kg per square meter.\n* American Society of Anesthesiologists physical status grade I-II.\n\nExclusion Criteria:\n\n* Patient refusal.\n* History of chronic pain therapy.\n* Infection at the injection site.","FEMALE","21 Years","64 Years",{"count":64,"type":65},70,"ESTIMATED","INTERVENTIONAL",[68],"NA","A large number of patients undergoing major surgical procedures for the management of breast cancer complain of acute and chronic postoperative pain. Morphine administration for acute pain after mastectomy surgery has many side effects. Regional block techniques, such as paravertebral block and thoracic epidural anaesthesia, have possible complications and technical difficulties. So, we will discuss adding dexmedetomidine as an adjuvant to bupivacaine for serratus-intercostal versus erector-spinae plane block to relieve post-mastectomy pain.",[71],"Analgesia",[73],"Analgesia, Mastectomy, Nerve Block, Bupivacaine","NOT_YET_RECRUITING","2026-07-03",{"date":77,"type":78},"2026-07-07","ACTUAL",{"date":80,"type":65},"2026-07",{"date":82,"type":65},"2027-02",{"name":5,"class":6}]