[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643941":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":30,"responsibleParty":76,"collaborators":10,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":10,"studyType":91,"phases":10,"briefSummary":92,"conditions":93,"keywords":99,"overallStatus":106,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Sklifosovsky Institute of Emergency Care","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"CT Image Review Cohort",null,"Anonymized CT scans of the thoracolumbar spine (T9-L3) obtained from eligible patients aged 18 to 65 years and reviewed independently by six raters to assess inter-rater and intra-rater reproducibility of CT-based evaluation of facet joint and intervertebral disc degenerative changes",[13],"Diagnostic Test: Computed Tomography Image Review",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Computed Tomography Image Review","Independent review of anonymized thoracolumbar CT scans by six raters for assessment of degenerative changes in facet joints and intervertebral discs using the Pathria scale, as well as measurement of facet joint space width and angulation.",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Ivan Lvov, PhD","CONTACT","+34 654 902 306","dr.speleolog@gmail.com",{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},"Vasiliy Karanadze, PhD","+7 903 565-68-30","karanadzevneuro@gmail.com",[31],{"facility":32,"status":10,"city":33,"state":10,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Sklifosovsky Research Institute for Emergency Medicine","Moscow","129090","Russia","RU",{"type":38,"coordinates":39},"Point",[40,41],37.61781,55.75204,{"lat":41,"lon":40},[44,48,51,54,56,58,60,62,64,66,68,70,72,74],{"name":45,"role":23,"phone":46,"phoneExt":10,"email":47},"Vasiliy Karanadze, MD, PhD","+7 (495) 280-15-61","sklif@zdrav.mos.ru",{"name":49,"role":50,"phone":10,"phoneExt":10,"email":10},"Andrey Grin, MD, PhD","PRINCIPAL_INVESTIGATOR",{"name":52,"role":53,"phone":10,"phoneExt":10,"email":10},"Aleksandr Talypov, MD, PhD","SUB_INVESTIGATOR",{"name":55,"role":53,"phone":10,"phoneExt":10,"email":10},"Anton Kordonsky, MD, PhD",{"name":57,"role":53,"phone":10,"phoneExt":10,"email":10},"Vasily Karandze, MD, PhD",{"name":59,"role":53,"phone":10,"phoneExt":10,"email":10},"Ivan Lvov, MD, PhD",{"name":61,"role":53,"phone":10,"phoneExt":10,"email":10},"Mikhail Kucherov, MD",{"name":63,"role":53,"phone":10,"phoneExt":10,"email":10},"Rinat Abdrafiev, MD",{"name":65,"role":53,"phone":10,"phoneExt":10,"email":10},"Aleksandr Tupikin, MD",{"name":67,"role":53,"phone":10,"phoneExt":10,"email":10},"Layla Khamidova, MD, PhD",{"name":69,"role":53,"phone":10,"phoneExt":10,"email":10},"Roman Elokhovskiy, MD, PhD",{"name":71,"role":53,"phone":10,"phoneExt":10,"email":10},"Ksenia Dmitrenko, MD",{"name":73,"role":53,"phone":10,"phoneExt":10,"email":10},"Maria Nanoyan, MD",{"name":75,"role":53,"phone":10,"phoneExt":10,"email":10},"Olga Minkina, MD",{"type":50,"investigatorFullName":59,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"External investigator","100643941","reliability-and-reproducibility-of-ct-based-facet-joint-measurements-in-patients-with-aospine-type-a2-a3-and-a4-thoracolumbar-fractures-100643941",false,"NCT07670039","Reliability and Reproducibility of CT-Based Facet Joint Measurements in Patients With AOSpine Type A2, A3, and A4 Thoracolumbar Fractures","REFACT","Inclusion Criteria:\n\n* patient age from 18 to 50 years;\n* thoracolumbar fracture classified as AOSpine type A2, A3, or A4;\n* availability of CT images covering vertebral levels from Th9 to L3;\n* absence of imaging artifacts at the levels planned for assessment.\n\nExclusion Criteria:\n\n* bone density of the thoracolumbar junction vertebrae below 100 HU;\n* systemic bone or joint disorders associated with changes in the FJs or intervertebral discs, including diffuse idiopathic skeletal hyperostosis, ankylosing spondylitis, rheumatoid arthritis, or other comparable conditions;\n* previous spinal surgery, including procedures performed without implants;\n* fractures with distraction or translational injury of the posterior supporting column.","ALL","18 Years","65 Years",{"count":89,"type":90},12,"ESTIMATED","OBSERVATIONAL","The Reliability Evaluation of Facet joint Assessment by Computed Tomography in thoracolumbar fractures (REFACT) study aims to evaluate how consistently different specialists assess thoracolumbar facet joints on computed tomography (CT) images in patients with AOSpine type A2, A3, or A4 thoracolumbar fractures.\n\nThe main questions are:\n\n* How consistently do different raters classify facet joint degeneration using the Pathria grading system?\n* How consistently do different raters measure facet joint angle and mean facet joint space width on CT images?\n* How reproducible are these assessments when the same rater repeats the measurements after a one-month interval?\n\nThe study will use anonymized retrospective CT DICOM datasets obtained from the institutional imaging archive. Six independent raters (three neurosurgeons and three radiology specialists) will evaluate the same CT datasets using a standardized measurement protocol. Each rater will perform two independent assessment rounds separated by a one-month washout period. The results will be used to determine the inter-rater and intra-rater reliability of qualitative and quantitative CT-based facet joint assessment methods.",[94,95,96,97,98],"Facet Joint Arthritis","Facet Joints; Degeneration","Facet Joint Disease","Intervertebral Disk Degeneration","Pathria Classification",[100,101,102,103,104,105],"Thoracolumbar Spine","Facet Joint","Intervertebral Disc","Computed Tomography","interobserver reliability","intraobserver reliability","NOT_YET_RECRUITING","2026-07-13",{"date":109,"type":110},"2026-07-15","ACTUAL",{"date":112,"type":90},"2026-08-01",{"date":114,"type":90},"2026-12-01",{"name":5,"class":6},1]