[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650630":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":96,"collaborators":25,"id":99,"slug":100,"hasResults":101,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":25,"eligibilityCriteria":105,"healthyVolunteers":101,"sex":106,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":25,"studyType":112,"phases":113,"briefSummary":115,"conditions":116,"keywords":120,"overallStatus":123,"whyStopped":25,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},{"fullName":5,"class":6},"Sir Run Run Shaw Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Remote Intervention Group","EXPERIMENTAL","Participants will receive home non-invasive respiratory support combined with active remote management.",[13,14],"Other: Remote Management","Other: Remote Monitoring Only",{"label":16,"type":17,"description":18,"interventionNames":19},"Monitoring Control Group","ACTIVE_COMPARATOR","Participants will receive home non-invasive respiratory support with remote monitoring only.",[14],[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Remote Management","Participants will receive home non-invasive respiratory support combined with active remote management. This includes regular analysis of ventilation data, assessment of oxygenation status, risk prediction, and remote parameter adjustment by a respiratory therapist.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Remote Monitoring Only","Participants will receive home non-invasive respiratory support with remote monitoring only. No active intervention will be performed by the study team based on the data. Patients will continue with standard care from their primary physician.",[16,9],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Huiqing Ge, MD, PhD","CONTACT","+86 13588706787","gehq@zju.edu.cn",[37,54,69,82],{"facility":38,"status":25,"city":39,"state":40,"zip":25,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Henan Provincial People's Hospital","Zhengzhou","Henan","China","CN",{"type":44,"coordinates":45},"Point",[46,47],113.64861,34.75778,{"lat":47,"lon":46},[50],{"name":51,"role":33,"phone":52,"phoneExt":25,"email":53},"Qiang Kui, MD","+86 13460317523","syhxzzggyx@163.com",{"facility":55,"status":25,"city":56,"state":57,"zip":58,"country":41,"countryCode":42,"cosmosGeoPoint":59,"geoPoint":63,"contacts":64},"The Second Xiangya Hospital of Central South University","Changsha","Hunan","410006",{"type":44,"coordinates":60},[61,62],112.97087,28.19874,{"lat":62,"lon":61},[65],{"name":66,"role":33,"phone":67,"phoneExt":25,"email":68},"Liucun Li","+86 0731-852959999","xyeyyibd@sina.com",{"facility":70,"status":25,"city":71,"state":72,"zip":73,"country":41,"countryCode":42,"cosmosGeoPoint":74,"geoPoint":78,"contacts":79},"Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University","Hangzhou","Zhejiang","310016",{"type":44,"coordinates":75},[76,77],120.16142,30.29365,{"lat":77,"lon":76},[80],{"name":81,"role":33,"phone":34,"phoneExt":25,"email":35},"Huiqing Ge",{"facility":83,"status":25,"city":84,"state":72,"zip":85,"country":41,"countryCode":42,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"Taizhou Hospital of Integrated Traditional Chinese and Western Medicine","Wenling","317523",{"type":44,"coordinates":87},[88,89],121.38416,28.37524,{"lat":89,"lon":88},[92],{"name":93,"role":33,"phone":94,"phoneExt":25,"email":95},"Ting Jiang","+86 13758692956","13758692956@139.com",{"type":97,"investigatorFullName":81,"investigatorTitle":98,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Director, Respiratory Care Department","100650630","remote-intervention-versus-routine-monitoring-in-copd-patients-with-chronic-hypercapnia-receiving-home-non-invasive-respiratory-support-100650630",false,"NCT07751003","Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory Support","A Randomized Controlled Trial of Remote Intervention Versus Routine Monitoring in COPD Patients With Chronic Hypercapnia Receiving Home Non-invasive Respiratory Support","Inclusion Criteria:\n\n* Meets the diagnostic criteria for Chronic Obstructive Pulmonary Disease (COPD) with confirmed persistent airflow limitation by spirometry.\n* Hospitalized due to an acute exacerbation of COPD.\n* Stable daytime arterial blood gas analysis showing PaCO₂ ≥ 50 mmHg, with hypoxemia.\n* Already receiving or planned to receive long-term home non-invasive respiratory support.\n* Capable of using a smartphone or tablet for video communication and has internet access.\n* Willing to participate and provides written informed consent.\n\nExclusion Criteria:\n\n* Concurrent severe pulmonary diseases (e.g., active tuberculosis, diffuse pulmonary fibrosis, advanced lung cancer).\n* Chronic respiratory failure primarily caused by non-COPD conditions (e.g., neuromuscular disease, chest wall deformity, or severe obesity hypoventilation syndrome).\n* Severe cognitive impairment or psychiatric illness that would prevent cooperation with remote management.\n* Other severe systemic diseases with an expected survival of less than 1 year (e.g., advanced malignancy).\n* Pregnant or lactating women.","ALL","40 Years","80 Years",{"count":110,"type":111},236,"ESTIMATED","INTERVENTIONAL",[114],"NA","This study is a randomized controlled trial designed to compare the effectiveness of active remote intervention versus passive monitoring alone in patients with Chronic Obstructive Pulmonary Disease (COPD) and chronic hypercapnic respiratory failure who are receiving home non-invasive respiratory support. The primary goal is to evaluate the impact on health-related quality of life and the frequency of acute exacerbations over a 12-month period.",[117,118,119],"COPD (Chronic Obstructive Pulmonary Disease)","Acute Exacerbation of COPD","Hypercapnia",[121,122],"Home management","Telehealth","NOT_YET_RECRUITING","2026-08-03",{"date":126,"type":127},"2026-08-06","ACTUAL",{"date":129,"type":111},"2027-08-01",{"date":131,"type":111},"2028-12-31",{"name":5,"class":6},4]