[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572870":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":22,"centralContacts":26,"locations":31,"responsibleParty":48,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":10,"maxAge":10,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":68,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Shanghai 6th People's Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Conventional TOaST with bilateral strap muscle suspension",null,"Participants undergoing conventional transoral and submental thyroidectomy. In this group, the linea alba cervicalis is opened caudally toward the suprasternal notch to establish the operative working space. Bilateral symmetric suspension of the strap muscles is performed to standardize surgical exposure.",{"label":13,"type":10,"description":14,"interventionNames":15},"Modified TOaST with caudal linea alba preservation","Participants undergoing modified transoral and submental thyroidectomy. In this group, the linea alba cervicalis is opened only in its cranial portion, with intentional preservation of a visible caudal linea alba-strap muscle fascial bridge. Bilateral symmetric suspension of the strap muscles is performed to create a centered operative window. If exposure is inadequate, the caudal linea alba opening may be extended and the case will be recorded as technical conversion to conventional TOaST.",[16],"Procedure: Modified TOaST with caudal linea alba preservation",[18],{"type":19,"name":13,"description":20,"armGroupLabels":21,"otherNames":10},"PROCEDURE","The modified procedure consists of cranial limited opening of the linea alba cervicalis with intentional preservation of the caudal linea alba-strap muscle fascial bridge. Bilateral symmetric suspension of the strap muscles is performed to maintain a centered operative window for thyroid lobectomy and, when indicated, ipsilateral central compartment lymph node dissection. If exposure is inadequate, the caudal linea alba may be further opened for safety.",[13],[23],{"name":24,"affiliation":5,"role":25},"Ling Zhan, Doctor","PRINCIPAL_INVESTIGATOR",[27],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","08615821120972","rebecca0428zhan@163.com",[32],{"facility":33,"status":34,"city":35,"state":10,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Shanghai Sixth People's Hospital","RECRUITING","Shanghai","200233","China","CN",{"type":40,"coordinates":41},"Point",[42,43],121.45806,31.22222,{"lat":43,"lon":42},[46],{"name":24,"role":28,"phone":29,"phoneExt":10,"email":47},"15821120972@163.com",{"type":25,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Ling Zhan","Principal Investigator","100572870","renovated-prediction-model-for-difficult-transoral-and-submental-endoscopic-thyroidectomy-100572870",false,"NCT06738888","Renovated Prediction Model for Difficult Transoral and Submental Endoscopic Thyroidectomy","A Functional-oriented Modification of TOaST Based on Partial Preservation of the Lines Alba Cervical","Inclusion Criteria:\n\n* Clinical diagnosis of differentiated thyroid cancer with a maximum diameter not exceeding 4 cm\n* Clinical diagnosis of benign thyroid nodule with a maximum diameter not exceeding 6 cm\n* Absence of suspicious lateral lymph nodes or distant metastases\n\nExclusion Criteria:\n\n* Participants with fusion or fixation of lymph nodes in the neck\n* Participants with history of neck surgery or radiation\n* Participants with vocal fold fixation by preoperative fibrolaryngoscope\n* Participants with preoperative examination suggestive of extrathyroidal invasion\n* Participants with a significantly restricted neck and\u002For jaw","ALL",{"count":60,"type":61},300,"ESTIMATED","OBSERVATIONAL","The investigators have previously proposed a prediction model for difficult transoral and submental thyroidectomy through a retrospective study. In order to better promote transoral and submental endoscopic approach for thyroid surgery and to set up an appropriate training course, the investigators aim to refine the procedure through a prospective study.",[65,66,67],"Thyroid Cancer","Thyroid Diseases","Thyroid Nodule",[69,70,71],"Endoscopic thyroidectomy","Transoral and submental approach","Prediction model","2026-08-05",{"date":74,"type":75},"2026-08-10","ACTUAL",{"date":77,"type":75},"2024-05-01",{"date":79,"type":61},"2028-12-31",{"name":5,"class":6},1]