[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647903":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":18,"responsibleParty":27,"collaborators":18,"id":29,"slug":30,"hasResults":31,"nctId":32,"briefTitle":33,"officialTitle":34,"acronym":18,"eligibilityCriteria":35,"healthyVolunteers":31,"sex":36,"minAge":37,"maxAge":18,"enrollmentInfo":38,"targetDuration":18,"studyType":41,"phases":42,"briefSummary":44,"conditions":45,"keywords":47,"overallStatus":53,"whyStopped":18,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":18},{"fullName":5,"class":6},"University of Groningen","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Meaning-centered intervention","EXPERIMENTAL","* Participants receive a meaning-centered intervention consisting of six 1-hour online sessions led by a trainer.\n* Interventions: Behavioral: Meaning-centered intervention for individuals who tend to feel down or anxious",[13],"Behavioral: Meaning-centered intervention for individuals who tend to feel down or anxious",{"label":15,"type":16,"description":17,"interventionNames":18},"Waitlist control","NO_INTERVENTION","\\- No task or intervention is assigned to participants in this arm.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Meaning-centered intervention for individuals who tend to feel down or anxious","* Six 1-hour individual online sessions, approximately every 4 days\n* Sessions led by a certified trainer based on intervention manual\n* Four sources of meaning will be explored: personal life story, dealing with life's limitations, creating one's own life, and meaningful experiences\n* Participants follow intervention using intervention the workbook\n* Homework assignments designed to deepen participants' experience and reflection on meaning in their daily lives",[9],[26],"Meaning-centered intervention for internalizing symptoms adapted from the intervention \"Meaning-centered intervention for youth worrying about their weight and shape\".",{"type":28,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100647903","replication-meaning-centered-intervention-for-internalizing-symptoms-100647903",false,"NCT07714954","Replication: Meaning-centered Intervention for Internalizing Symptoms","Testing the Efficacy of a Meaning-centered Intervention for Individuals Who Tend to Feel Down or Anxious: a Replication","Inclusion Criteria:\n\n* heightened internalizing symptoms (depression and\u002For anxiety symptoms) as indicated by PHQ-4 score of 2 or above on either the anxiety or depression subscale\n\nExclusion Criteria:\n\n* receiving psychotherapeutic treatment for a depressive or anxiety disorder\n* suicidality","ALL","18 Years",{"count":39,"type":40},140,"ESTIMATED","INTERVENTIONAL",[43],"NA","Young adults who experience depression and\u002For anxiety symptoms (i.e., internalizing symptoms) will be randomly allocated to a six-session meaning-centered intervention condition or a waitlist condition. Both conditions receive the same questionnaires at baseline, post assessment (intervention condition: immediately after the final session; waitlist: four weeks after baseline), and follow-up.\n\nThe researchers hypothesize that a meaning-centered intervention for individuals with internalizing symptoms will increase participants' meaning in life and reduce their internalizing symptoms at post assessment and 4-week follow-up when compared to a waitlist condition.",[46],"Depression and\u002For Anxiety Symptoms",[48,49,50,51,52],"meaning in life","meaning-centered intervention","internalizing symptoms","depression symptoms","anxiety symptoms","NOT_YET_RECRUITING","2026-08-11",{"date":56,"type":57},"2026-08-14","ACTUAL",{"date":59,"type":40},"2026-10",{"date":61,"type":40},"2028-02",{"name":5,"class":6}]