[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650137":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":28,"responsibleParty":112,"collaborators":115,"id":127,"slug":128,"hasResults":129,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":133,"eligibilityCriteria":134,"healthyVolunteers":135,"sex":136,"minAge":137,"maxAge":10,"enrollmentInfo":138,"targetDuration":10,"studyType":141,"phases":10,"briefSummary":142,"conditions":143,"keywords":145,"overallStatus":147,"whyStopped":10,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":157},{"fullName":5,"class":6},"RTI International","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Early Pregnancy Cohort",null,"* 18 years or older\n* Gestational age at enrollment: Between 12.0 and 13.6 weeks of gestation\n* Pregnant individuals receiving care at participating clinical sites with intent of delivering at study hospital\n* Consent to participate in study procedures through 6 weeks postpartum",{"label":13,"type":10,"description":14,"interventionNames":10},"Late Pregnancy Cohort","* 18 years or older\n* Gestational age at enrollment: greater than or equal to 28.0 weeks gestational age\n* Clinical indications of risk (FGR \\\u003C10th percentile or report of decreased fetal movement)\n* Pregnant individual receiving care at participating clinical sites with intent of delivering at study hospital\n* Consent to participate in study procedures through 6 weeks postpartum",[16],{"name":17,"affiliation":5,"role":18},"Elizabeth McClure, PhD","PRINCIPAL_INVESTIGATOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","919-316-3773","mcclure@rti.org",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Carla Bann, PhD","919-485-2773","cmb@rti.org",[29,48,65,81,97],{"facility":30,"status":10,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"University of California Center for Stillbirth Prevention","San Diego","California","92093","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-117.16472,32.71571,{"lat":40,"lon":39},[43,47],{"name":44,"role":21,"phone":45,"phoneExt":10,"email":46},"Mana Parast, MD, PhD","858-534-8631","mparast@health.ucsd.edu",{"name":44,"role":18,"phone":10,"phoneExt":10,"email":10},{"facility":49,"status":10,"city":50,"state":50,"zip":51,"country":34,"countryCode":35,"cosmosGeoPoint":52,"geoPoint":56,"contacts":57},"The Collaborative Action for Research to End Stillbirth (CARES) Research Center at Columbia University","New York","10027",{"type":37,"coordinates":53},[54,55],-74.00597,40.71427,{"lat":55,"lon":54},[58,62,63],{"name":59,"role":21,"phone":60,"phoneExt":10,"email":61},"Uma Reddy, MD, MPH","240-401-3605","uma.reddy@yale.edu",{"name":59,"role":18,"phone":10,"phoneExt":10,"email":10},{"name":64,"role":18,"phone":10,"phoneExt":10,"email":10},"Xiao Xu, PhD",{"facility":66,"status":10,"city":67,"state":68,"zip":69,"country":34,"countryCode":35,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Oregon Health & Science University","Portland","Oregon","97239",{"type":37,"coordinates":71},[72,73],-122.67621,45.52345,{"lat":73,"lon":72},[76,80],{"name":77,"role":21,"phone":78,"phoneExt":10,"email":79},"Karen Gibbins, MD, MSCI","503-494-2101","gibbins@ohsu.edu",{"name":77,"role":18,"phone":10,"phoneExt":10,"email":10},{"facility":82,"status":10,"city":83,"state":84,"zip":85,"country":34,"countryCode":35,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"University of Utah","Salt Lake City","Utah","84112",{"type":37,"coordinates":87},[88,89],-111.89105,40.76078,{"lat":89,"lon":88},[92,96],{"name":93,"role":21,"phone":94,"phoneExt":10,"email":95},"Robert Silver, MD","801-581-8425","bob.silver@hsc.utah.edu",{"name":93,"role":18,"phone":10,"phoneExt":10,"email":10},{"facility":98,"status":10,"city":99,"state":100,"zip":101,"country":34,"countryCode":35,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"Old Dominion University","Norfolk","Virginia","23529",{"type":37,"coordinates":103},[104,105],-76.28522,36.84681,{"lat":105,"lon":104},[108],{"name":109,"role":21,"phone":110,"phoneExt":10,"email":111},"George Saade, MD","757-446-5257","saadegr@odu.edu",{"type":18,"investigatorFullName":113,"investigatorTitle":114,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Elizabeth McClure","Senior Research Epidemiologist",[116,117,118,120,122,124],{"name":98,"class":6},{"name":82,"class":6},{"name":119,"class":6},"Columbia University",{"name":121,"class":6},"University of California, San Diego",{"name":123,"class":6},"Oregon Health and Science University",{"name":125,"class":126},"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","NIH","100650137","research-on-advanced-diagnostics-and-management-of-all-pregnancies-to-prevent-stillbirth-roadmaps-100650137",false,"NCT07745101","Research On Advanced Diagnostics and Management of All Pregnancies to Prevent Stillbirth (ROADMAPS)","NICHD Stillbirth Research Consortium: Research on Advanced Diagnostics and Management of All Pregnancies to Prevent Stillbirth (ROADMAPS)","ROADMAPS","Early Pregnancy Cohort Inclusion Criteria\n\n* 18 years of age\n* Gestational age at enrollment: Between 12.0 and 13.6 weeks of gestation\n* Pregnant individuals receiving care at participating clinical sites with intent of delivering at study hospital\n* Consent to participate in study procedures through 6 weeks postpartum\n\nLate Pregnancy Cohort\n\n* 18 years or older\n* Gestational age at enrollment: greater than or equal to 28.0 weeks gestational age\n* Clinical indications of risk FGR \\\u003C10th percentile or report of decreased fetal movement)\n* Pregnant individual receiving care at participating clinical sites with intent of delivering at study hospital\n* Consent to participate in study procedures through 6 weeks postpartum\n\nExclusion Criteria:\n\n* Evidence of fetal genetic anomaly or major structural malformation\n* Known fetal aneuploidy based on chorionic villus sampling\n* Positive cell-free fetal DNA screening for aneuploidy\n* Multifetal gestation\n* Less than 18 years of age\n* Not fluent in either English or Spanish",true,"FEMALE","18 Years",{"count":139,"type":140},7000,"ESTIMATED","OBSERVATIONAL","The primary objective of the Stillbirth Research Consortium (SBRC) longitudinal cohort study is to develop and evaluate a robust multivariable prediction model to identify pregnancies at \\\u003C14 weeks gestation that are at increased risk of stillbirth or fetal growth restriction (FGR), often reflecting underlying placental dysfunction.\n\nSecondary objectives include:\n\n* To evaluate placental pathology among cases and selected controls using standardized Amsterdam criteria.\n* To identify key aspects of perinatal nutrition contributing to placental dysfunction\n* To determine relationships between maternal biomarkers, placental pathology and energetics, with the goal of identifying biomarkers predictive of placental dysfunction\n* To develop a risk stratification model for pregnancies complicated by decreased fetal movements (DFM)",[144],"Stillbirth",[144,146],"Fetal growth restriction","NOT_YET_RECRUITING","2026-07-29",{"date":150,"type":151},"2026-08-04","ACTUAL",{"date":153,"type":140},"2026-08-01",{"date":155,"type":140},"2030-07-31",{"name":5,"class":6},5]