[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648004":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":28,"locations":38,"responsibleParty":57,"collaborators":59,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":25,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":87,"whyStopped":25,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Ochsner Health System","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Outpatient Sequential Cervical Ripening","EXPERIMENTAL","Those assigned to sequential cervical ripening will be scheduled with a trained physician for placement of Dilapan-STM osmotic cervical dilators in the outpatient setting at 12 to 24 hours prior to their scheduled labor and delivery admission. Upon admission to labor and delivery, sequential patients will have Dilapan-S removed during clinical vaginal exam and will receive misoprostol 25 mcg every two hours up to 8 doses until modified Bishop score is greater than 4, warranting transition to oxytocin infusion.",[13],"Combination Product: Sequential Cervical Ripening",{"label":15,"type":16,"description":17,"interventionNames":18},"Inpatient Combined Cervical Ripening","ACTIVE_COMPARATOR","Those randomized to scheduled induction of labor in the inpatient setting will present as scheduled to labor unit, at which time they will undergo clinical assessment and will receive placement of Dilapan-S by a trained physician along with misoprostol 25 mcg every 2 hours up to 8 doses or until clinical exam demonstrates modified Bishop score greater than 4, warranting transition to oxytocin infusion.",[19],"Combination Product: Inpatient Combined Cervical Ripening",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"COMBINATION_PRODUCT","Sequential Cervical Ripening",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":27,"otherNames":25},[15],[29,34],{"name":30,"role":31,"phone":32,"phoneExt":25,"email":33},"Frank Williams, MD","CONTACT","205-994-4820","frank.williams2@ochsner.org",{"name":35,"role":31,"phone":36,"phoneExt":25,"email":37},"Ken Bode","504-842-1936","ken.bode@ochsner.org",[39],{"facility":40,"status":25,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Ochsner Baptist","New Orleans","Louisiana","70115","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-90.07507,29.95465,{"lat":50,"lon":49},[53,55],{"name":30,"role":31,"phone":54,"phoneExt":25,"email":33},"504-899-9311",{"name":30,"role":56,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"type":58,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[60],{"name":61,"class":62},"Medicem International","UNKNOWN","100648004","ripening-approaches-for-prompt-induction-and-delivery---sequential-versus-concurrent-dilapan-s-and-misoprostol-to-achieve-vaginal-delivery-rapid-ds-100648004",false,"NCT07717502","Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)","RAPID-DS","Inclusion Criteria:\n\n* Nulliparous patients with singleton pregnancies with vertex lie at term receiving prenatal care that are eligible for outpatient cervical ripening will be eligible\n\nExclusion Criteria:\n\n* age less than 18,\n* suspected major fetal anomalies (including suspected or proven chromosome anomalies, congenital cardiac disease expected to require neonatal intervention, and multiple anomalies suggestive of a complex syndrome),\n* fetal growth restriction\n* oligohydramnios\n* prior full thickness\n* uterine scar\n* placenta previa,\n* low-lying placenta,\n* premature rupture of amniotic membranes,\n* cervical dilation \\> 2 cm\n* modified Bishop score \\> 4\n* residence greater than 60 minutes from the hospital","FEMALE","18 Years",{"count":73,"type":74},260,"ESTIMATED","INTERVENTIONAL",[77],"NA","The purpose of this study is to compare the effectiveness of sequential versus combined multimodal cervical ripening strategies to achieve vaginal delivery within 24 hours among nulliparous patients with singleton, vertex pregnancies at term undergoing induction of labor.",[80,81],"Nulliparous Women Who Scheduled for Labor Induction","Pregnancy",[83,84,85,86],"nulliparous","labor induction","cervical ripening","misoprostol","NOT_YET_RECRUITING","2026-07-16",{"date":90,"type":91},"2026-07-21","ACTUAL",{"date":93,"type":74},"2026-08",{"date":95,"type":74},"2027-12",{"name":5,"class":6},1]