[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100526651":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":27,"locations":32,"responsibleParty":49,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":10,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"Ruijin Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with good coronary collaterals",null,"Coronary collateral circulation development was graded according to the Rentrop score, grade 2 (partial filling of the epicardial segment by collateral vessels); grade 3 (complete filling of the epicardial artery by collateral vessels) were defined as good coronary collateral circulation.",[13],"Procedure: Coronary angiography",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients with poor coronary collaterals","Coronary collateral circulation development was graded according to the Rentrop score, grade 0 (no filling of any collateral vessels) and grade 1 (filling of side branches of the artery to be perfused by collateral vessels without visualization of the epicardial segment) were defined as poor coronary collateral circulation.",[13],[19],{"type":20,"name":21,"description":10,"armGroupLabels":22,"otherNames":10},"PROCEDURE","Coronary angiography",[9,15],[24],{"name":25,"affiliation":5,"role":26},"Fenghua Ding, PhD, MD","STUDY_CHAIR",[28],{"name":25,"role":29,"phone":30,"phoneExt":10,"email":31},"CONTACT","0086 021 64370045","ruijindfh@126.com",[33],{"facility":34,"status":35,"city":36,"state":10,"zip":10,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Ruijin Hospital, Shanghai Jiao Tong University School of Medicine","RECRUITING","Shanghai","China","CN",{"type":40,"coordinates":41},"Point",[42,43],121.45806,31.22222,{"lat":43,"lon":42},[46],{"name":47,"role":29,"phone":30,"phoneExt":10,"email":48},"Jian Li","ruijincrc@126.com",{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100526651","risk-factors-and-outcomes-in-coronary-chronic-total-occlusion-100526651",false,"NCT06137521","Risk Factors and Outcomes in Coronary Chronic Total Occlusion","Risk Factors and Outcomes in Patients With Stable Coronary Artery Disease and Coronary Chronic Total Occlusion","Inclusion Criteria:\n\n* Age ≥18 years; Patients with angina or silent ischemia and documented ischemia; Patients with CTO ≥ 3months\n\nExclusion Criteria:\n\n* eGFR\\\u003C15mL\u002F(min·1.73m2); Chronic heart failure with NYHA grade ≥3; Had a history of coronary artery bypass grafting; Had received a percutaneous coronary intervention within the prior 3 months; Malignant tumor or immune system disorders; Pulmonary heart disease","ALL","18 Years",{"count":61,"type":62},3000,"ESTIMATED","OBSERVATIONAL","This study aims to assess the risk factors and evaluate the long-term outcomes of patients with coronary chronic total occlusion (CTO) treated with percutaneous coronary intervention or medical treatment.",[66,67],"Chronic Total Occlusion","Coronary Artery Disease","2026-08-17",{"date":70,"type":71},"2026-08-18","ACTUAL",{"date":73,"type":71},"2010-01-01",{"date":75,"type":62},"2027-03-01",{"name":5,"class":6},1]