[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650566":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":12,"collaborators":10,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":22,"eligibilityCriteria":23,"healthyVolunteers":18,"sex":24,"minAge":25,"maxAge":10,"enrollmentInfo":26,"targetDuration":29,"studyType":30,"phases":10,"briefSummary":31,"conditions":32,"keywords":34,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":47,"leadSponsor":49,"locationsCount":10},{"fullName":5,"class":6},"Eye & ENT Hospital of Fudan University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Adults Undergoing Nasal Surgery Under General Anesthesia",null,"This prospective observational cohort includes adults aged 18 years or older undergoing nasal surgery under general anesthesia. No study-specific intervention will be administered. Anesthetic management, surgical care, prophylactic antiemetic therapy, analgesia, and postoperative treatment will be determined by routine clinical practice at each participating center. Perioperative patient, anesthesia, surgical, and medication-related factors will be recorded, and participants will be followed to assess postoperative nausea and vomiting and other postoperative complications.",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Wenxian Li","Professor, Chief Physician, Director of the Department of Anesthesiology","100650566","risk-factors-for-postoperative-nausea-and-vomiting-after-nasal-surgery-under-general-anesthesia-100650566",false,"NCT07749079","Risk Factors for Postoperative Nausea and Vomiting After Nasal Surgery Under General Anesthesia","Risk Factors for Postoperative Nausea and Vomiting in Patients Undergoing Nasal Surgery Under General Anesthesia: A Multicenter Prospective Observational Cohort Study","N-PONV","Inclusion Criteria:\n\n* Scheduled to undergo nasal surgery under general anesthesia\n* Aged 18 years or older\n* Willing and able to provide written informed consent\n\nExclusion Criteria:\n\n* Unable to cooperate with study procedures or complete study assessments for any reason, including language barriers, cognitive impairment, or inability to complete the questionnaires\n* Considered unsuitable for participation by the investigator","ALL","18 Years",{"count":27,"type":28},1000,"ESTIMATED","6 Months","OBSERVATIONAL","The goal of this observational study is to learn how often postoperative nausea and vomiting occur in adults undergoing nasal surgery under general anesthesia and to identify factors associated with these events. The study will also describe other postoperative complications and factors that may affect recovery.\n\nThe main questions it aims to answer are:\n\n* How many participants experience nausea, retching, or vomiting within 24 hours after surgery?\n* Which patient characteristics, anesthesia-related factors, surgical factors, and perioperative medications are associated with postoperative nausea and vomiting?\n* What other postoperative complications and nasal-related symptoms occur after surgery?\n\nApproximately 1,000 adults undergoing nasal surgery under general anesthesia at three hospitals in China will be enrolled. This is an observational study, and participation will not change the anesthesia, surgery, medications, or other medical care selected by the treating clinical team.\n\nParticipants will:\n\n* Complete assessments before surgery about their medical history, previous nausea or vomiting, anxiety, sleep, and recovery status\n* Receive routine anesthesia and surgical care\n* Be assessed for nausea, retching, vomiting, pain, nasal discomfort, and other complications during the first 24 hours after surgery\n* Complete follow-up assessments after surgery, including follow-up by telephone after discharge, for up to 6 months\n\nThe study will use information from participant questionnaires, medical records, anesthesia records, and postoperative follow-up assessments.",[33],"PONV",[35,33,36,37,38,39,40],"Postoperative nausea and vomiting","Nasal surgery","General anesthesia","Risk factors","Prospective cohort study","Perioperative complications","NOT_YET_RECRUITING","2026-08-01",{"date":44,"type":45},"2026-08-06","ACTUAL",{"date":42,"type":28},{"date":48,"type":28},"2027-06-30",{"name":5,"class":6}]