[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609922":3},{"organization":4,"outcomesModule":7,"designInfo":19,"detailedDescription":25,"studyPopulation":18,"armGroups":26,"interventions":32,"overallOfficials":18,"centralContacts":38,"locations":44,"responsibleParty":178,"collaborators":18,"id":180,"slug":181,"hasResults":182,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":18,"eligibilityCriteria":186,"healthyVolunteers":182,"sex":187,"minAge":188,"maxAge":18,"enrollmentInfo":189,"targetDuration":18,"studyType":192,"phases":193,"briefSummary":194,"conditions":195,"keywords":197,"overallStatus":47,"whyStopped":18,"lastUpdateSubmitDate":199,"lastUpdatePostDateStruct":200,"startDateStruct":203,"completionDateStruct":205,"leadSponsor":207,"locationsCount":208},{"fullName":5,"class":6},"Avisi Technologies Inc.","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":18},[9],{"measure":10,"description":11,"timeFrame":12},"Proportion of subjects (eyes) achieving a ≥ 20% reduction in mean diurnal intraocular pressure","The eye is filled with a special fluid. The intraocular pressure is the amount of fluid that builds up in the eye. The primary outcome is the number of people whose eye pressure went down by at least 20%.","12 Months",[14],{"measure":15,"description":16,"timeFrame":17},"Percentage change in mean diurnal IOP","How much the average eye pressure during the day went up or down, shown as a percent.","12 months",null,{"allocation":20,"interventionModel":21,"interventionModelDescription":18,"primaryPurpose":22,"observationalModel":18,"timePerspective":18,"maskingInfo":23},"NA","SINGLE_GROUP","TREATMENT",{"masking":24,"maskingDescription":18,"whoMasked":18},"NONE","To evaluate the safety and effectiveness of VisiPlate Aqueous Shunt to lower intraocular pressure (IOP) in subjects with open-angle glaucoma for whom medical and surgical treatments have failed.",[27],{"label":28,"type":29,"description":18,"interventionNames":30},"Treatment Arm","EXPERIMENTAL",[31],"Device: VisiPlate Glaucoma Implant",[33],{"type":34,"name":35,"description":36,"armGroupLabels":37,"otherNames":18},"DEVICE","VisiPlate Glaucoma Implant","Implant (micro-shunt) for glaucoma patients",[28],[39],{"name":40,"role":41,"phone":42,"phoneExt":18,"email":43},"Katherine Lee","CONTACT","12816100251","kati@avisitech.com",[45,59,70,79,88,98,107,117,123,133,139,148,158,169],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":18},"Arizona Advanced Eye Research","RECRUITING","Glendale","Arizona","85306","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-112.18599,33.53865,{"lat":57,"lon":56},{"facility":60,"status":61,"city":62,"state":63,"zip":64,"country":51,"countryCode":52,"cosmosGeoPoint":65,"geoPoint":69,"contacts":18},"Advanced Vision Care","WITHDRAWN","Los Angeles","California","90067",{"type":54,"coordinates":66},[67,68],-118.24368,34.05223,{"lat":68,"lon":67},{"facility":71,"status":47,"city":72,"state":63,"zip":73,"country":51,"countryCode":52,"cosmosGeoPoint":74,"geoPoint":78,"contacts":18},"North Bay Eye Associates, Inc.","Petaluma","94954",{"type":54,"coordinates":75},[76,77],-122.63665,38.23242,{"lat":77,"lon":76},{"facility":80,"status":47,"city":81,"state":63,"zip":82,"country":51,"countryCode":52,"cosmosGeoPoint":83,"geoPoint":87,"contacts":18},"Sacramento Eye Consultants","Sacramento","95815",{"type":54,"coordinates":84},[85,86],-121.4944,38.58157,{"lat":86,"lon":85},{"facility":89,"status":47,"city":90,"state":91,"zip":92,"country":51,"countryCode":52,"cosmosGeoPoint":93,"geoPoint":97,"contacts":18},"ICON Eye Care","Grand Junction","Colorado","81501",{"type":54,"coordinates":94},[95,96],-108.55065,39.06387,{"lat":96,"lon":95},{"facility":99,"status":47,"city":100,"state":100,"zip":101,"country":51,"countryCode":52,"cosmosGeoPoint":102,"geoPoint":106,"contacts":18},"NYC Retina","New York","10003",{"type":54,"coordinates":103},[104,105],-74.00597,40.71427,{"lat":105,"lon":104},{"facility":108,"status":47,"city":109,"state":110,"zip":111,"country":51,"countryCode":52,"cosmosGeoPoint":112,"geoPoint":116,"contacts":18},"Scheie Eye Institute","Philadelphia","Pennsylvania","19104",{"type":54,"coordinates":113},[114,115],-75.16362,39.95238,{"lat":115,"lon":114},{"facility":118,"status":61,"city":109,"state":110,"zip":119,"country":51,"countryCode":52,"cosmosGeoPoint":120,"geoPoint":122,"contacts":18},"Wills Eye Hospital","19107",{"type":54,"coordinates":121},[114,115],{"lat":115,"lon":114},{"facility":124,"status":47,"city":125,"state":126,"zip":127,"country":51,"countryCode":52,"cosmosGeoPoint":128,"geoPoint":132,"contacts":18},"Glaucoma Associates of Texas","Dallas","Texas","75231",{"type":54,"coordinates":129},[130,131],-96.80667,32.78306,{"lat":131,"lon":130},{"facility":134,"status":47,"city":125,"state":126,"zip":135,"country":51,"countryCode":52,"cosmosGeoPoint":136,"geoPoint":138,"contacts":18},"University of Texas Southwestern","75390",{"type":54,"coordinates":137},[130,131],{"lat":131,"lon":130},{"facility":140,"status":47,"city":141,"state":126,"zip":142,"country":51,"countryCode":52,"cosmosGeoPoint":143,"geoPoint":147,"contacts":18},"Houston Eye Associates","Houston","77025",{"type":54,"coordinates":144},[145,146],-95.36327,29.76328,{"lat":146,"lon":145},{"facility":149,"status":47,"city":150,"state":151,"zip":152,"country":51,"countryCode":52,"cosmosGeoPoint":153,"geoPoint":157,"contacts":18},"The Eye Centers of Racine & Kenosha","Kenosha","Wisconsin","53142",{"type":54,"coordinates":154},[155,156],-87.82119,42.58474,{"lat":156,"lon":155},{"facility":159,"status":47,"city":160,"state":18,"zip":161,"country":162,"countryCode":163,"cosmosGeoPoint":164,"geoPoint":168,"contacts":18},"Lynette Venter","Bloemfontein","9301","South Africa","ZA",{"type":54,"coordinates":165},[166,167],26.214,-29.12107,{"lat":167,"lon":166},{"facility":170,"status":47,"city":171,"state":18,"zip":172,"country":162,"countryCode":163,"cosmosGeoPoint":173,"geoPoint":177,"contacts":18},"Pretoria Eye Institute","Pretoria","0007",{"type":54,"coordinates":174},[175,176],28.18783,-25.74486,{"lat":176,"lon":175},{"type":179,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100609922","safety-and-effectiveness-of-the-visiplate-aqueous-shunt-in-patients-with-refractory-open-angle-glaucoma-100609922",false,"NCT07220876","Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma","A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial of the Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma","Inclusion Criteria:\n\n* Open angle, pseudoexfoliative or pigmentary glaucoma\n* IOP at preoperative visit of ≥ 20mmHg and ≤ 40mmHg\n* Visual field mean deviation score of -3dB or worse\n* Area of healthy, free and mobile conjunctiva in the target quadrant\n* Shaffer angle grade ≥ 2 in the target quadrant\n\nExclusion Criteria:\n\n* Angle closure glaucoma\n* Congenital, neovascular or other secondary glaucomas\n* Previous intraocular surgery, with the exception of uncomplicated cataract surgery\n* Previous glaucoma shunt\u002Fvalve in the target quadrant\n* Clinically significant inflammation or infection in the study eye within 30 days prior to the operative visit\n* History of corneal surgery, corneal opacities or corneal disease\n* Retinal or optic nerve disorders, either degenerative or evolutive, that are not associated with the existing glaucoma condition","ALL","45 Years",{"count":190,"type":191},165,"ESTIMATED","INTERVENTIONAL",[20],"A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial",[196],"Open Angle Glaucoma (OAG)",[198],"Glaucoma","2026-10-06",{"date":201,"type":202},"2026-10-07","ACTUAL",{"date":204,"type":202},"2025-11-07",{"date":206,"type":191},"2027-10",{"name":5,"class":6},14]