[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650659":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":40,"locations":46,"responsibleParty":62,"collaborators":23,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":23,"eligibilityCriteria":69,"healthyVolunteers":66,"sex":70,"minAge":71,"maxAge":23,"enrollmentInfo":72,"targetDuration":23,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":48,"whyStopped":23,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"USMARI Research & Innovation Centre","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Skincare regimen","OTHER","The skincare regimen consist of cleanser, toner, serum, day cream and night cream",[13,14,15,16,17],"Other: Cleanser","Other: Toner","Other: Serum","Other: Day cream","Other: Night cream",[19,24,28,32,36],{"type":10,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"Cleanser","Each participant will be provided with a Gentle deep cleanser, 100 mL containing Cocos Nucifera (Coconut) Oil, to be applied for 4 weeks according to the specified instructions.",[9],null,{"type":10,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Toner","Each participant will be provided with a Dewy cheeks revitalising toner, 100 mL containing Cocos Nucifera (Coconut) Oil, to be applied for 4 weeks according to the specified instructions.",[9],{"type":10,"name":29,"description":30,"armGroupLabels":31,"otherNames":23},"Serum","Each participant will be provided with a Deep serum, 30 mL containing Cocos Nucifera (Coconut) Oil, to be applied for 4 weeks according to the specified instructions.",[9],{"type":10,"name":33,"description":34,"armGroupLabels":35,"otherNames":23},"Day cream","Each participant will be provided with a moisturizing day cream, 50 gm containing Cocos Nucifera (Coconut) Oil, to be applied for 4 weeks according to the specified instructions.",[9],{"type":10,"name":37,"description":38,"armGroupLabels":39,"otherNames":23},"Night cream","Each participant will be provided with a moisturizing night cream, 50 gm containing Cocos Nucifera (Coconut) Oil, to be applied for 4 weeks according to the specified instructions.",[9],[41],{"name":42,"role":43,"phone":44,"phoneExt":23,"email":45},"Siti Nur Hanis Mamood, PhD","CONTACT","+60167572670","hanis@usmari.org.my",[47],{"facility":5,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Petaling Jaya","Selangor","47810","Malaysia","MY",{"type":55,"coordinates":56},"Point",[57,58],101.60671,3.10726,{"lat":58,"lon":57},[61],{"name":42,"role":43,"phone":44,"phoneExt":23,"email":45},{"type":63,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100650659","safety-and-efficacy-of-skincare-products-for-managing-mild-to-moderate-acne-in-individuals-with-sensitive-skin-100650659",false,"NCT07749469","Safety and Efficacy of Skincare Products for Managing Mild to Moderate Acne in Individuals With Sensitive Skin","Inclusion Criteria:\n\n* Healthy Malaysian women and men\n* Fitzpatrick skin type II-V\n* Age above 18 years old\n* Individuals with sensitive skin identify through sensitive skin survey (Corazza et al., 2022) and lactic acid sting test (LAST).\n* Individuals with mild to moderate acne, based on Comprehensive Acne Severity Scale (CASS)\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding women, or those planning pregnancy during the study period.\n* Individuals with documented autoimmune diseases or other conditions that may affect immune response or skin barrier function.\n* Individuals with a history of severe skin sensitivity reactions, including frequent intense erythema, swelling, or intolerable burning in response to topical products.\n* Individuals with severe acne requiring medical treatment or systemic treatment such as nodulocystic acne.\n* Individuals with active inflammatory or allergic dermatological conditions affecting the face, such as atopic dermatitis, eczema, or psoriasis, which may compromise skin barrier function or interfere with study assessments.\n* Individuals who have undergone cosmetic or dermatological procedures such as -chemical peel, microneedling, or any procedures aimed at improving acne, within 3 months prior to the study.\n* Individuals currently taking medical or hormonal treatments that may interfere with study outcomes, including anti-inflammatory agents, corticosteroids, or other medication interfering with study objectives.\n* Individuals with known allergy or hypersensitivity to any ingredients found in the product.","ALL","18 Years",{"count":73,"type":74},34,"ESTIMATED","INTERVENTIONAL",[77],"NA","To investigate the safety and efficacy of a skincare regimen in individuals with mild to moderate acne and sensitive skin. The study duration is 4 weeks and the skin assessment will be carried out at baseline and week 4.\n\nThe main questions this study aims to answer are:\n\n1. To investigate the safety of the skincare regimen products in managing mild to moderate acne in individuals with sensitive skin.\n2. To determine the efficacy of the skincare regimen products in managing mild to moderate acne in individuals with sensitive skin.\n3. To assess the participants' satisfaction with the skincare regimen products in managing mild to moderate acne in individuals with sensitive skin.",[80],"Acne",[82,83,84],"skincare","sensitive skin","acne","2026-08-04",{"date":87,"type":88},"2026-08-06","ACTUAL",{"date":90,"type":88},"2026-06-01",{"date":92,"type":74},"2026-12-30",{"name":5,"class":6},1]