[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100657117":3},{"organization":4,"outcomesModule":7,"designInfo":21,"detailedDescription":20,"studyPopulation":20,"armGroups":30,"interventions":41,"overallOfficials":49,"centralContacts":53,"locations":58,"responsibleParty":74,"collaborators":76,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":20,"eligibilityCriteria":86,"healthyVolunteers":82,"sex":87,"minAge":88,"maxAge":20,"enrollmentInfo":89,"targetDuration":20,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":102,"whyStopped":20,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":20},[9],{"measure":10,"description":11,"timeFrame":12},"Horizontal Bone Gain (mm) Measured by Cone-Beam Computed Tomography (CBCT)","Horizontal bone gain will be measured in millimeters (mm) by comparing CBCT images obtained at baseline and follow-up. Measurements will be performed using computer-based imaging software to quantify changes in horizontal alveolar ridge width at the treated site.","1 year after crown delivery",[14,17],{"measure":15,"description":16,"timeFrame":12},"Implant Survival Assessed by Clinical Examination","Implant survival will be assessed by the treating provider through clinical examination at the specified follow-up time point. An implant will be considered surviving if it remains present and in function at the time of evaluation.",{"measure":18,"description":19,"timeFrame":12},"Pink Esthetic Score (PES) Assessed by a Blinded Examiner","Peri-implant esthetic outcomes will be evaluated by a blinded examiner using the Pink Esthetic Score (PES). The PES will be determined according to the predefined components of the scoring system, with higher scores indicating a more favorable peri-implant soft-tissue esthetic outcome.",null,{"allocation":22,"interventionModel":23,"interventionModelDescription":20,"primaryPurpose":24,"observationalModel":20,"timePerspective":20,"maskingInfo":25},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":26,"maskingDescription":20,"whoMasked":27},"DOUBLE",[28,29],"PARTICIPANT","OUTCOMES_ASSESSOR",[31,36],{"label":32,"type":33,"description":20,"interventionNames":34},"Sandwich bone augmentation","EXPERIMENTAL",[35],"Procedure: Sandwich bone augmentation",{"label":37,"type":38,"description":20,"interventionNames":39},"Mixed bone augmentation","ACTIVE_COMPARATOR",[40],"Procedure: Mixed bone augmentation",[42,46],{"type":43,"name":32,"description":44,"armGroupLabels":45,"otherNames":20},"PROCEDURE","The exposed threads on the buccal side of the implant will be grafted with three distinct layers of grafting materials.",[32],{"type":43,"name":37,"description":47,"armGroupLabels":48,"otherNames":20},"The exposed threads on the buccal side of the implant will be grafted with three grafting materials mixed together.",[37],[50],{"name":51,"affiliation":5,"role":52},"Guo-Hao Lin, DDS, MS","PRINCIPAL_INVESTIGATOR",[54],{"name":51,"role":55,"phone":56,"phoneExt":20,"email":57},"CONTACT","415-476-1731","guo-hao.lin@ucsf.edu",[59],{"facility":60,"status":20,"city":61,"state":62,"zip":63,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"Periodontology Clinic, UCSF School of Dentistry","San Francisco","California","94143","United States","US",{"type":67,"coordinates":68},"Point",[69,70],-122.41942,37.77493,{"lat":70,"lon":69},[73],{"name":51,"role":55,"phone":56,"phoneExt":20,"email":20},{"type":75,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR",[77],{"name":78,"class":79},"Geistlich Pharma AG","INDUSTRY","100657117","sandwich-vs-mixed-bone-augmentation-for-implant-placement-100657117",false,"NCT07832565","Sandwich vs. Mixed Bone Augmentation for Implant Placement","Comparison of Dental Implant Placement With Simultaneous Sandwich Bone Augmentation vs. Mixed Bone Augmentation: a Randomized Controlled Pilot Study","Inclusion Criteria:\n\n* Minimum dentition of 20 permanent teeth\n* Single edentulous site at maxillary premolar, canine, lateral incisor, or central incisor\n* Adjacent teeth present with sufficient clearance for an implant crown\n* Ridge width between 4 mm and 7 mm at the edentulous site\n\nExclusion Criteria:\n\n* Systemic criteria:\n\n  * Current heavy smokers (\\>10 cigarettes per day) or heavy smokers who quitted less than 1 year\n  * Pregnancy or lactating mothers\n  * Diseases of the immune system or any medical condition that may influence the treatment outcome (for examples uncontrolled diabetes (HbA1c \\>7), uncontrolled cardiovascular disease, neurologic or psychiatric disorders, systemic infections, history of radiation therapy in the head and neck area, current use of oral bisphosphonates for \\>3 years or history of IV bisphosphonates use, current alcoholism or drug abuse, etc.)\n* Intraoral criteria:\n\n  * Acute infection at\u002For adjacent to the edentulous site (e.g., sinus tract, swelling, etc.)\n  * Observable gingival changes due to use of medications such as calcium antagonists, anticonvulsives, immunosuppressants, anti-inflammatory medications, etc.)\n  * Generalized uncontrolled dental diseases, e.g. caries, periodontal diseases, etc.\n  * Uncontrolled periodontal disease\n  * Poor oral hygiene (\\>20% plaque score)\n* CBCT criteria:\n\n  • More than 7 mm of alveolar ridge with at the edentulous site present on CBCT scans\n* Intraoperative criteria:\n\n  * An implant without primary stability \\>35N","ALL","18 Years",{"count":90,"type":91},30,"ESTIMATED","INTERVENTIONAL",[94],"NA","This study is being done to see which of two common grafting techniques-mixing two different grafting materials or layering two grafting materials-works better to augment bone volume next to your dental implant(s). We want to know which technique results in better bone augmentation.",[97],"Peri-implant Bone and Soft Tissues",[99,100,101],"bone dehiscence","bone fenestration","dental implants","NOT_YET_RECRUITING","2026-09-18",{"date":105,"type":106},"2026-09-22","ACTUAL",{"date":108,"type":91},"2026-11-01",{"date":110,"type":91},"2028-12-31",{"name":5,"class":6},1]