[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648911":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":10,"locations":19,"responsibleParty":106,"collaborators":10,"id":108,"slug":109,"hasResults":110,"nctId":111,"briefTitle":112,"officialTitle":112,"acronym":113,"eligibilityCriteria":114,"healthyVolunteers":110,"sex":115,"minAge":116,"maxAge":117,"enrollmentInfo":118,"targetDuration":10,"studyType":121,"phases":10,"briefSummary":122,"conditions":123,"keywords":125,"overallStatus":79,"whyStopped":10,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":140},{"fullName":5,"class":6},"Universitaire Ziekenhuizen KU Leuven","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients in therapeutic failure or relapse",null,"Any child, adolescent or young adult, treated for a pediatric tumor or leukemia, in therapeutic failure or relapse without standard treatment option, not eligible \u002F refusal of inclusion in a clinical study open on the territory and treated with an innovative drug within the framework of a compassionate use or outside marketing authorization, in one of the centers of the Belgian pediatric hemato-oncology centers",[13],"Other: data collection",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"data collection","In particular, the patient's demographic data, medical history, previous and concomitant treatments, data on the treatment of interest (legal framework, compassionate use\u002F off-label), dosage, start date, etc.), clinical data will be collected. biological (including molecular profiling of the tumor if available) and radiological follow-up, information on adverse effects.",[9],[20,39,53,63,77,92],{"facility":21,"status":22,"city":23,"state":10,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"University Hospital Antwerp","NOT_YET_RECRUITING","Antwerp","2650","Belgium","BE",{"type":28,"coordinates":29},"Point",[30,31],4.40026,51.22047,{"lat":31,"lon":30},[34],{"name":35,"role":36,"phone":37,"phoneExt":10,"email":38},"Toon Van Genechten, MD","CONTACT","+32 3 821 58 58","toon.vangenechten@uza.be",{"facility":40,"status":22,"city":41,"state":10,"zip":42,"country":25,"countryCode":26,"cosmosGeoPoint":43,"geoPoint":47,"contacts":48},"Hôpital Universitaire des Enfants Reine Fabiola (HUDERF)","Brussels","1020",{"type":28,"coordinates":44},[45,46],4.34878,50.85045,{"lat":46,"lon":45},[49],{"name":50,"role":36,"phone":51,"phoneExt":10,"email":52},"Pierluigi Calò, MD","+32 2 477 26 78","Pierluigi.CALO@hubruxelles.be",{"facility":54,"status":22,"city":41,"state":10,"zip":55,"country":25,"countryCode":26,"cosmosGeoPoint":56,"geoPoint":58,"contacts":59},"Cliniques Universitaires Saint-Luc","1200",{"type":28,"coordinates":57},[45,46],{"lat":46,"lon":45},[60],{"name":61,"role":36,"phone":62,"phoneExt":10,"email":10},"An Van Damme, MD","+32 2 764 23 50",{"facility":64,"status":22,"city":65,"state":10,"zip":66,"country":25,"countryCode":26,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"University Hospital Gent","Ghent","9000",{"type":28,"coordinates":68},[69,70],3.71667,51.05,{"lat":70,"lon":69},[73],{"name":74,"role":36,"phone":75,"phoneExt":10,"email":76},"Bram De Wilde, MD","+32 9 332 48 12","bram.dewilde@uzgent.be",{"facility":78,"status":79,"city":80,"state":10,"zip":81,"country":25,"countryCode":26,"cosmosGeoPoint":82,"geoPoint":86,"contacts":87},"University Hospital 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Adolescents and Young Adults","(SACHA)","Inclusion Criteria:\n\n* Age ≤ 25 at the time of inclusion in the study\n* Patient with a pediatric malignancy (solid tumor or leukemia), or other related condition\n* Patient not currently enrolled on any other trial for ongoing therapeutic purposes\n* Patient treated with compassionate use of experimental drugs or off-label administration use of anti-cancer medicines first approved in adults after 2007 in Europe\n* Patient discussed in a Pediatric multidisciplinary tumor boards (MDTB) to validate the inclusion in the SACHA study\n* Consent to participate by the patient or his\u002Fher legal representatives in the study if required by ta particular national jurisdiction\n\nExclusion Criteria:\n\n* Patient receiving the drug within a clinical trial.\n* Oral refusal to participate to the study, by the patient or his\u002Fher parents\u002Flegal representatives.","ALL","0 Years","25 Years",{"count":119,"type":120},1600,"ESTIMATED","OBSERVATIONAL","It involves collecting safety and efficacy data, under the actual conditions of use of off label and compassionate use medicines in children and adolescents approved in humans before 2007, using a validated tool (Ennov EDC) and relying on the network recognised pediatric hemato-oncology centers in Belgium and responsible for the organization of Pediatric National tumor boards which discuss each case of relapse in order to define the best therapeutic options.",[124],"Pediatric Cancer",[126,16,127,128,129,130],"observational","childhood cancer","pediatric cancer","off label medication","CU medication","2026-07-22",{"date":133,"type":134},"2026-07-27","ACTUAL",{"date":136,"type":120},"2026-07",{"date":138,"type":120},"2030-12-31",{"name":5,"class":6},6]