[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100653384":3},{"organization":4,"outcomesModule":7,"designInfo":24,"detailedDescription":27,"studyPopulation":28,"armGroups":29,"interventions":23,"overallOfficials":23,"centralContacts":23,"locations":23,"responsibleParty":36,"collaborators":23,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":23,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":23,"studyType":54,"phases":23,"briefSummary":55,"conditions":56,"keywords":23,"overallStatus":58,"whyStopped":23,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":23},{"fullName":5,"class":6},"Kanuni Sultan Suleyman Training and Research Hospital","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":23},[9],{"measure":10,"description":11,"timeFrame":12},"Serum CTGF\u002FCCN2 Level","Serum Connective Tissue Growth Factor (CTGF\u002FCCN2) levels will be measured in patients with chronic plantar fasciitis and asymptomatic controls.","At baseline",[14,17,20],{"measure":15,"description":16,"timeFrame":12},"Pain Severity","Pain severity will be assessed using a Visual Analog Scale (VAS), and its association with serum CTGF\u002FCCN2 levels will be evaluated.",{"measure":18,"description":19,"timeFrame":12},"Foot Function Index","Functional status will be assessed using the Foot Function Index (FFI), and its association with serum CTGF\u002FCCN2 levels will be evaluated.",{"measure":21,"description":22,"timeFrame":12},"Plantar Fascia Thickness","Plantar fascia thickness will be measured by musculoskeletal ultrasonography, and its association with serum CTGF\u002FCCN2 levels will be evaluated.",null,{"allocation":23,"interventionModel":23,"interventionModelDescription":23,"primaryPurpose":23,"observationalModel":25,"timePerspective":26,"maskingInfo":23},"CASE_CONTROL","PROSPECTIVE","This is a single-center observational study including patients with chronic plantar fasciitis and asymptomatic controls. Serum CTGF\u002FCCN2 levels will be evaluated, and their associations with clinical and ultrasonographic characteristics will be assessed.","Adults aged 18-65 years, including patients with chronic plantar fasciitis and asymptomatic controls without clinical or ultrasonographic findings of plantar fasciitis.",[30,33],{"label":31,"type":23,"description":32,"interventionNames":23},"Chronic Plantar Fasciitis Group","Patients with chronic plantar fasciitis diagnosed based on clinical and ultrasonographic evaluation.",{"label":34,"type":23,"description":35,"interventionNames":23},"Control Group","Asymptomatic participants without clinical or ultrasonographic findings of plantar fasciitis.",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"PRINCIPAL_INVESTIGATOR","Zeynep Karakuzu Güngör","Physical Medicine and Rehabilitation Specialist","100653384","serum-ctgf-in-chronic-plantar-fasciitis-100653384",false,"NCT07785453","Serum CTGF in Chronic Plantar Fasciitis","Association of Serum Connective Tissue Growth Factor (CTGF\u002FCCN2) Levels With Pain and Functional Status in Patients With Chronic Plantar Fasciitis","Inclusion Criteria:\n\n* Age 18-65 years.\n* Written informed consent.\n* For the patient group: chronic plantar heel pain for at least 3 months, pain during the first steps in the morning or after prolonged rest, tenderness over the medial calcaneal tubercle, and clinical and ultrasonographic findings consistent with chronic plantar fasciitis.\n* For the control group: asymptomatic individuals without a previous diagnosis or clinical and ultrasonographic findings of plantar fasciitis.\n\nExclusion Criteria:\n\n* Tarsal tunnel syndrome, calcaneal stress fracture, plantar fascia rupture, Achilles tendinopathy, heel fat pad syndrome, plantar fibromatosis, or other foot conditions causing plantar heel pain.\n* Diabetes mellitus.\n* Inflammatory rheumatic diseases or gout.\n* Chronic kidney or liver disease.\n* Malignancy.\n* Active infection or autoimmune disease\n* Pregnancy.\n* Previous foot or ankle surgery.\n* Corticosteroid injection, platelet-rich plasma (PRP), prolotherapy, extracorporeal shock wave therapy (ESWT), or other interventional treatment to the affected heel within the previous 3 months.\n* Serious systemic conditions that may affect serum CTGF\u002FCCN2 levels.",true,"ALL","18 Years","65 Years",{"count":52,"type":53},60,"ESTIMATED","OBSERVATIONAL","This observational study aims to evaluate serum Connective Tissue Growth Factor (CTGF\u002FCCN2) levels in patients with chronic plantar fasciitis compared with asymptomatic controls. The study will also assess the associations between serum CTGF levels and clinical and ultrasonographic characteristics of chronic plantar fasciitis.",[57],"Plantar Fasciitis","NOT_YET_RECRUITING","2026-08-21",{"date":61,"type":62},"2026-08-25","ACTUAL",{"date":64,"type":53},"2026-08-30",{"date":66,"type":53},"2026-11-15",{"name":5,"class":6}]