[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100657873":3},{"organization":4,"outcomesModule":7,"designInfo":27,"detailedDescription":30,"studyPopulation":31,"armGroups":32,"interventions":26,"overallOfficials":39,"centralContacts":44,"locations":26,"responsibleParty":50,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":26,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":26,"enrollmentInfo":64,"targetDuration":26,"studyType":67,"phases":26,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":76,"whyStopped":26,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":26},{"fullName":5,"class":6},"Assiut University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":26},[9],{"measure":10,"description":11,"timeFrame":12},"Mean serum EBI-3 protein level","Mean serum Epstein-Barr virus-induced gene 3 (EBI-3) protein concentration measured by ELISA in patients with Behçet's disease compared with healthy controls.","Baseline",[14,17,20,23],{"measure":15,"description":16,"timeFrame":12},"Serum EBI-3 level according to disease activity","Mean serum EBI-3 protein concentration according to Behçet's Disease Current Activity Form (BDCAF) score.",{"measure":18,"description":19,"timeFrame":12},"Serum EBI-3 level in patients with vascular involvement","Mean serum EBI-3 protein concentration in patients with and without vascular involvement",{"measure":21,"description":22,"timeFrame":12},"Serum EBI-3 level in patients with ocular involvement","Mean serum EBI-3 protein concentration in patients with and without ocular involvement.",{"measure":24,"description":25,"timeFrame":12},"Serum EBI-3 level in patients with neurological involvement","Mean serum EBI-3 protein concentration in patients with and without neurological involvement.",null,{"allocation":26,"interventionModel":26,"interventionModelDescription":26,"primaryPurpose":26,"observationalModel":28,"timePerspective":29,"maskingInfo":26},"CASE_CONTROL","CROSS_SECTIONAL","Behçet's disease is a chronic multisystem inflammatory disorder. Serum EBI-3 protein levels may reflect inflammatory activity.\n\nThis observational study will include adult patients diagnosed with Behçet's disease according to the International Criteria for Behçet's Disease and age-matched healthy controls. Serum EBI-3 protein levels will be measured by ELISA.","Adult patients with Behçet's disease attending the Physical Medicine, Rheumatology and Rehabilitation Department at Assiut University Hospitals, and healthy controls.",[33,36],{"label":34,"type":26,"description":35,"interventionNames":26},"Behçet's Disease","Patients diagnosed with Behçet's disease according to the International Criteria for Behçet's Disease.",{"label":37,"type":26,"description":38,"interventionNames":26},"Healthy Controls","Age-matched healthy individuals without autoimmune or inflammatory diseases.",[40],{"name":41,"affiliation":42,"role":43},"Gehan I Abdelraziq, prof","Physical Medicine, Rheumatology and Rehabilitation Department, Assiut University Hospitals","STUDY_CHAIR",[45],{"name":46,"role":47,"phone":48,"phoneExt":26,"email":49},"Shrouk S Mohamed, Resident","CONTACT","01004638754","shrouk.18313202@med.aun.edu.eg",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Shrouk Samir Mohamed","Resident Physician, Department of Physical Medicine, Rheumatology and Rehabilitation","100657873","serum-ebi-3-protein-levels-in-behets-disease-100657873",false,"NCT07845162","Serum EBI-3 Protein Levels in Behçet's Disease","Serum Epstein-Barr Virus-induced Gene 3 Protein Levels in Patients With Behçet's Disease","Inclusion Criteria:\n\n* \\- Age 18 years or older\n* Diagnosis of Behçet's disease according to the International Criteria for Behçet's Disease (cases)\n* Healthy individuals without autoimmune or inflammatory diseases (controls)\n* Written informed consent\n\nExclusion Criteria:\n\n* \\- Other autoimmune disorders (RA, SLE, psoriatic arthritis, ankylosing spondylitis)\n* Acute or chronic infection\n* Malignancy or history of malignancy\n* Chronic liver disease or advanced chronic kidney disease\n* Pregnancy or lactation\n* Vasculitis caused by diseases other than Behçet's disease",true,"ALL","18 Years",{"count":65,"type":66},90,"ESTIMATED","OBSERVATIONAL","This cross-sectional study aims to evaluate serum Epstein-Barr virus-induced gene 3 (EBI-3) protein levels in patients with Behçet's disease compared with healthy controls.",[70],"Behçet Disease",[72,73,74,75],"Behçet's disease","EBI-3 Serum","biomarker","Assiut","NOT_YET_RECRUITING","2026-09-22",{"date":79,"type":80},"2026-09-28","ACTUAL",{"date":82,"type":66},"2026-09-26",{"date":84,"type":66},"2028-01-25",{"name":5,"class":6}]