[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100656589":3},{"organization":4,"outcomesModule":7,"designInfo":30,"detailedDescription":29,"studyPopulation":29,"armGroups":35,"interventions":46,"overallOfficials":29,"centralContacts":51,"locations":61,"responsibleParty":270,"collaborators":29,"id":272,"slug":273,"hasResults":274,"nctId":275,"briefTitle":276,"officialTitle":276,"acronym":277,"eligibilityCriteria":278,"healthyVolunteers":274,"sex":279,"minAge":280,"maxAge":29,"enrollmentInfo":281,"targetDuration":29,"studyType":284,"phases":285,"briefSummary":287,"conditions":288,"keywords":290,"overallStatus":295,"whyStopped":29,"lastUpdateSubmitDate":296,"lastUpdatePostDateStruct":297,"startDateStruct":300,"completionDateStruct":302,"leadSponsor":304,"locationsCount":305},{"fullName":5,"class":6},"Fondation Hôpital Saint-Joseph","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":29},[9],{"measure":10,"description":11,"timeFrame":12},"Proportion of Confirmed R0 Resections","R0 status assessed according to IASLC 2020 criteria using centralized pathology review and independent adjudication.","Perioperative",[14,18,22,26],{"measure":15,"description":16,"timeFrame":17},"QualitySurg list Implementation and Adoption","Measure individual and collective adherence to the list (usage rate, level of completeness).","During surgery",{"measure":19,"description":20,"timeFrame":21},"Medium-Term Oncological Results","overall survival (OS) and disease-free survival (DFS) at 2 years, and proportion of local or metastatic recurrences at 2 years.","2 years after surgery",{"measure":23,"description":24,"timeFrame":25},"Quality of the Surgical Procedure","Evaluate the impact on intraoperative and post-operative complications (morbidity, mortality, length of stay, especially in intensive care).","30 and 90 days after surgery",{"measure":27,"description":28,"timeFrame":17},"Sociological and Collaborative Aspects","Evaluate the impact on:\n\n* Interprofessional communication : obeservations, semi-structured interviews, self-administred questionnaire (Likert scale)\n* Team engagement: obeservations, semi-structured interviews, self-administred questionnaire (Likert scale)\n* Acceptability of the list in the operating room: obeservations, semi-structured interviews, self-administred questionnaire (Likert scale)",null,{"allocation":31,"interventionModel":32,"interventionModelDescription":29,"primaryPurpose":6,"observationalModel":29,"timePerspective":29,"maskingInfo":33},"RANDOMIZED","PARALLEL",{"masking":34,"maskingDescription":29,"whoMasked":29},"NONE",[36,42],{"label":37,"type":38,"description":39,"interventionNames":40},"QualitySurg Implementation Strategy","EXPERIMENTAL","Centers assigned to the intervention arm will first participate in a baseline control period during which eligible patients undergo lung cancer surgery according to usual practice without use of the QualitySurg list. During a subsequent intervention period, centers will implement the QualitySurg list, a structured intraoperative quality assessment tool combining a checklist, a to-do list, and a reporting system, supported by training, digital reporting tools, and performance feedback. Following completion of the randomized trial phase, centers will enter a prospective implementation phase in which continued, partial, modified, or discontinued use of the QualitySurg list will be observed under routine clinical practice conditions in order to assess maintenance of use and long-term adoption.",[41],"Other: QualitySurg List",{"label":43,"type":44,"description":45,"interventionNames":29},"Standard Surgical Practice","NO_INTERVENTION","Centers assigned to the control arm will continue their usual surgical practice throughout the randomized trial phase without implementation of the QualitySurg list. Following completion of the randomized trial phase, the QualitySurg list will be made available to these centers. During the subsequent prospective implementation phase, uptake, integration, patterns of use, and adoption of the QualitySurg list will be evaluated under routine clinical practice conditions without any mandatory requirement for implementation.",[47],{"type":6,"name":48,"description":49,"armGroupLabels":50,"otherNames":29},"QualitySurg List","The QualitySurg List is a collaborative intraoperative quality assessment tool for lung cancer surgery that combines a checklist, a to-do list, and a reporting system. The intervention includes implementation of the QualitySurg List, training of operating room personnel, access to a dedicated digital application integrated within the Epithor platform, and performance feedback through benchmarking of quality indicators. The tool is designed to support real-time assessment and documentation of surgical quality and to improve achievement of oncologically complete (R0) resections.",[37],[52,57],{"name":53,"role":54,"phone":55,"phoneExt":29,"email":56},"Olaf MERCIER","CONTACT","0033140948695","o.mercier@ghpsj.fr",{"name":58,"role":54,"phone":59,"phoneExt":29,"email":60},"Imène TRIAKI","0033140942330","itriaki@ghpsj.fr",[62,77,88,99,110,118,130,141,152,163,174,185,190,195,206,217,228,239,250,258],{"facility":63,"status":29,"city":64,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"CHU Angers","Angers","France","FR",{"type":68,"coordinates":69},"Point",[70,71],-0.55202,47.47156,{"lat":71,"lon":70},[74],{"name":75,"role":76,"phone":29,"phoneExt":29,"email":29},"AMMI Myriam","PRINCIPAL_INVESTIGATOR",{"facility":78,"status":29,"city":79,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":80,"geoPoint":84,"contacts":85},"Avicennes","Bobigny",{"type":68,"coordinates":81},[82,83],2.45012,48.90982,{"lat":83,"lon":82},[86],{"name":87,"role":76,"phone":29,"phoneExt":29,"email":29},"Emmanuel MARTINOD",{"facility":89,"status":29,"city":90,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"CHU Bordeaux","Bordeaux",{"type":68,"coordinates":92},[93,94],-0.58046,44.84124,{"lat":94,"lon":93},[97],{"name":98,"role":76,"phone":29,"phoneExt":29,"email":29},"Yanis BELAROUSSI",{"facility":100,"status":29,"city":101,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"CLCC Jean Perrin","Clermont-Ferrand",{"type":68,"coordinates":103},[104,105],3.08682,45.77969,{"lat":105,"lon":104},[108],{"name":109,"role":76,"phone":29,"phoneExt":29,"email":29},"Marc FILAIRE",{"facility":111,"status":29,"city":112,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":113,"geoPoint":117,"contacts":29},"CHU Dijon","Dijon",{"type":68,"coordinates":114},[115,116],5.01391,47.31344,{"lat":116,"lon":115},{"facility":119,"status":29,"city":120,"state":29,"zip":121,"country":65,"countryCode":66,"cosmosGeoPoint":122,"geoPoint":126,"contacts":127},"Hôpital Marie Lannelongue","Le Plessis-Robinson","92350",{"type":68,"coordinates":123},[124,125],2.27078,48.78889,{"lat":125,"lon":124},[128],{"name":129,"role":76,"phone":29,"phoneExt":29,"email":29},"Olaf Mercier",{"facility":131,"status":29,"city":132,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":133,"geoPoint":137,"contacts":138},"CHU Lille","Lille",{"type":68,"coordinates":134},[135,136],3.05512,50.63391,{"lat":136,"lon":135},[139],{"name":140,"role":76,"phone":29,"phoneExt":29,"email":29},"Axel PLAISANT",{"facility":142,"status":29,"city":143,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":144,"geoPoint":148,"contacts":149},"Chu Lyon","Lyon",{"type":68,"coordinates":145},[146,147],4.84789,45.74906,{"lat":147,"lon":146},[150],{"name":151,"role":76,"phone":29,"phoneExt":29,"email":29},"Jean Michel MAURY",{"facility":153,"status":29,"city":154,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":155,"geoPoint":159,"contacts":160},"Hôpital Nord","Marseille",{"type":68,"coordinates":156},[157,158],5.38107,43.29695,{"lat":158,"lon":157},[161],{"name":162,"role":76,"phone":29,"phoneExt":29,"email":29},"Pascal THOMAS",{"facility":164,"status":29,"city":165,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":166,"geoPoint":170,"contacts":171},"CHU Nantes","Nantes",{"type":68,"coordinates":167},[168,169],-1.55336,47.21725,{"lat":169,"lon":168},[172],{"name":173,"role":76,"phone":29,"phoneExt":29,"email":29},"Philippe LACOSTE",{"facility":175,"status":29,"city":176,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":177,"geoPoint":181,"contacts":182},"Bichat Claude-Bernard","Paris",{"type":68,"coordinates":178},[179,180],2.3488,48.85341,{"lat":180,"lon":179},[183],{"name":184,"role":76,"phone":29,"phoneExt":29,"email":29},"Pierre MORDANT",{"facility":186,"status":29,"city":176,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":187,"geoPoint":189,"contacts":29},"HEGP",{"type":68,"coordinates":188},[179,180],{"lat":180,"lon":179},{"facility":191,"status":29,"city":176,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":192,"geoPoint":194,"contacts":29},"Hôpital Tenon",{"type":68,"coordinates":193},[179,180],{"lat":180,"lon":179},{"facility":196,"status":29,"city":197,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":198,"geoPoint":202,"contacts":203},"CHU Poitiers","Poitiers",{"type":68,"coordinates":199},[200,201],0.34348,46.58261,{"lat":201,"lon":200},[204],{"name":205,"role":76,"phone":29,"phoneExt":29,"email":29},"Christophe JAYLE",{"facility":207,"status":29,"city":208,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":209,"geoPoint":213,"contacts":214},"CHU de Rennes","Rennes",{"type":68,"coordinates":210},[211,212],-1.67431,48.11109,{"lat":212,"lon":211},[215],{"name":216,"role":76,"phone":29,"phoneExt":29,"email":29},"Bertrand RICHARD DE LA TOUR",{"facility":218,"status":29,"city":219,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":220,"geoPoint":224,"contacts":225},"CHU Rouen","Rouen",{"type":68,"coordinates":221},[222,223],1.09932,49.44313,{"lat":223,"lon":222},[226],{"name":227,"role":76,"phone":29,"phoneExt":29,"email":29},"Jean-Marc BASTE",{"facility":229,"status":29,"city":230,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":231,"geoPoint":235,"contacts":236},"CHU Strasbourg","Strasbourg",{"type":68,"coordinates":232},[233,234],7.74553,48.58392,{"lat":234,"lon":233},[237],{"name":238,"role":76,"phone":29,"phoneExt":29,"email":29},"Pierre-Emmanuel FALCOZ",{"facility":240,"status":29,"city":241,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":242,"geoPoint":246,"contacts":247},"Hôpital Foch","Suresnes",{"type":68,"coordinates":243},[244,245],2.22929,48.87143,{"lat":245,"lon":244},[248],{"name":249,"role":76,"phone":29,"phoneExt":29,"email":29},"Edouard SAGE",{"facility":251,"status":29,"city":252,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":253,"geoPoint":257,"contacts":29},"CHU Toulouse","Toulouse",{"type":68,"coordinates":254},[255,256],1.44367,43.60426,{"lat":256,"lon":255},{"facility":259,"status":29,"city":260,"state":29,"zip":29,"country":65,"countryCode":66,"cosmosGeoPoint":261,"geoPoint":265,"contacts":266},"CHU Tours","Tours",{"type":68,"coordinates":262},[263,264],0.70398,47.39484,{"lat":264,"lon":263},[267,269],{"name":268,"role":54,"phone":29,"phoneExt":29,"email":29},"Antoine LEGRAS",{"name":268,"role":76,"phone":29,"phoneExt":29,"email":29},{"type":271,"investigatorFullName":29,"investigatorTitle":29,"investigatorAffiliation":29,"oldNameTitle":29,"oldOrganization":29},"SPONSOR","100656589","short--and-mid-term-therapeutic-prognostic-and-societal-impact-of-implementing-intraoperative-assessment-of-pulmonary-resection-quality-for-lung-cancer-100656589",false,"NCT07828938","Short- and Mid-term Therapeutic, Prognostic, and Societal Impact of Implementing Intraoperative Assessment of Pulmonary Resection Quality for Lung Cancer","QualitySurg","Inclusion Criteria:\n\n* Age ≥18 years\n* Have solid NSCLC clinical stage IA-IIIA (according to the 9th edition of the TNM) and be eligible for surgical resection.\n* Have a respiratory function and a state of performance (ECOG) allowing the surgical procedure.\n* Primary intervention for NSCLC, whether isolated or included in a multimodal regimen (neoadjuvant\u002Fadjuvant).\n* Intervention can be performed by minimally invasive surgery (VATS, RATS) or by thoracotomy.\n* Have given written informed consent.\n\nExclusion Criteria:\n\n* History of cancer less than five years old excluding non-melanocytic skin cancer prior to enrollment\n* Pure ground glass opacities regardless of tumor size\n* iterative re-interventions of the same stay (keep only the first planned intervention for the main analysis)\n* History of HIV infection, allogeneic stem cell or solid organ transplant\n* History of any hematological disease that is not considered to be in complete remission\n* Patients under guardianship or conservatorship\n* Patients deprived of their liberty or under judicial protection\n* Pregnant women","ALL","18 Years",{"count":282,"type":283},2400,"ESTIMATED","INTERVENTIONAL",[286],"NA","QUALITYSURG is a multicenter interventional study evaluating whether a collaborative intraoperative quality checklist (QualitySurg List) can improve the oncological quality of lung cancer resections. The study includes three phases: a Delphi consensus to define checklist contents, a cluster-randomized trial comparing checklist use versus standard care, and a prospective implementation phase assessing long-term adoption. The primary endpoint is the proportion of confirmed R0 resections according to 2020 IASLC criteria.Two optional ancillary studies are embedded within the main protocol. BIO-QualitySurg aims to evaluate biological markers of residual disease and develop the concept of a biological R0 resection using circulating tumor DNA (ctDNA), tissue biomarkers, and integrated molecular analyses. BIO-QualitySurg is complementary to the objectives of the European REALCARE project, which investigates ctDNA-based approaches for residual disease assessment and personalized cancer management. VIDEO-QualitySurg contributes to the broader objective of improving quality assessment and standardization of thoracic oncologic surgery through digital technologies and artificial intelligence.",[289],"Lung Cancer (Non-Small Cell)",[291,292,293,294],"Thoracic surgery","lung cancer","checklist","R0 resection","NOT_YET_RECRUITING","2026-09-14",{"date":298,"type":299},"2026-09-18","ACTUAL",{"date":301,"type":283},"2026-09-01",{"date":303,"type":283},"2030-03-01",{"name":5,"class":6},20]