[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659401":3},{"organization":4,"outcomesModule":7,"designInfo":34,"detailedDescription":40,"studyPopulation":33,"armGroups":41,"interventions":48,"overallOfficials":33,"centralContacts":56,"locations":66,"responsibleParty":90,"collaborators":33,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":33,"eligibilityCriteria":99,"healthyVolunteers":95,"sex":100,"minAge":101,"maxAge":33,"enrollmentInfo":102,"targetDuration":33,"studyType":105,"phases":106,"briefSummary":107,"conditions":108,"keywords":113,"overallStatus":69,"whyStopped":33,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"University Ghent","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":33},[9],{"measure":10,"description":11,"timeFrame":12},"change in cognition","score on SCOPA-COG","From enrollment to the end of intervention at 10 weeks",[14,17,20,23,26,29],{"measure":15,"description":16,"timeFrame":12},"change in motor symptoms","score of MDS-UPDRS III",{"measure":18,"description":19,"timeFrame":12},"change in balance and mobility","score of MiniBESTest \u002F Functional Gait Assessment",{"measure":21,"description":22,"timeFrame":12},"change in QOL","score of PDQ39",{"measure":24,"description":25,"timeFrame":12},"Speech handicap Index","score of perceived handicap - physical, functional and emotional",{"measure":27,"description":28,"timeFrame":12},"change in quality of voice (vowel formants, voice oncet time), motor speech and prosody","Praat-score (a free, open-source computer program) Motor Speech Profile - score (vocal tremor, diadochokinetic rates, and pitch\u002Fformant transitions) Loudness, intonation and speech intelligibility during reading (\"The North Wind and the Sun\") - 3 minutes of spontaneous speech",{"measure":30,"description":31,"timeFrame":32},"Change in maximum voluntary respiration rate","maximum volontary respiration frequency","From enrollment up to 10 weeks of intervention",null,{"allocation":35,"interventionModel":36,"interventionModelDescription":33,"primaryPurpose":37,"observationalModel":33,"timePerspective":33,"maskingInfo":38},"NA","SINGLE_GROUP","TREATMENT",{"masking":39,"maskingDescription":33,"whoMasked":33},"NONE","The Ronnie Gardiner Method (RGM) is a cheerful, structured, multi-sensory brain exercise method that utilizes rhythm and music to stimulate movement, speech, and cognition. RGM makes playful use of rhythm, music, movement, speech, hearing, sight, and touch. During practice, the participant reads the symbols and 'translates' them into the corresponding movement, which is performed to the rhythm of the music. Preliminary research suggests RGM may have added value in promoting mobility, cognition, and well-being in neurological patients (https:\u002F\u002Fwww.tandfonline.com\u002Fdoi\u002Ffull\u002F10.1080\u002F09638288.2024.2392037#d1e1192).\n\nThe RGM exercise series for which participants are registering is integrated in the \"Fit en Actief group classes\" organized by the Ghent Flemish Parkinson League - in collaboration with Ghent University Rehabilitation Sciences and Physiotherapy.\n\nThe classes will take place from October to December 2026 (10 weeks), with exercises taking place once a week for 1.5 hours (on Thursdays) in the practical classrooms of the Rehabilitation Sciences and Physiotherapy program (UH Ghent, B3). In addition to the exercise sessions themselves, participants will be asked to perform home exercises twice a week for 15 minutes.\n\nBefore and after the exercise series, participants will be invited to take a pre- and post-test including administrative data, cognition, motor symptoms, balance, QOL. The training process (home exercises, experiences) will be inventoried by temporary questionnaires.\n\nAfterwards, participants will be surveyed regarding changes in medication during the exercise series, changes in the frequency or content of (physio)therapy, and perceived changes in attention, memory, and planning.",[42],{"label":43,"type":44,"description":45,"interventionNames":46},"RGM","EXPERIMENTAL","10 weeks of RGM group training (1.5h\u002Fw) supplemented with home exercises and conventional care",[47],"Other: Ronnie Gardiner Method",[49],{"type":6,"name":50,"description":51,"armGroupLabels":52,"otherNames":53},"Ronnie Gardiner Method","1. Warm-up (10 min): light rhythmic movements to music; activation of coordination and attention.\n2. RGM Block 1 (30 min): cognitive-motor exercises incorporating color, sound, and movement elements (bilateral).\n3. Strength or interval segment (10 min): short strength\u002Fconditioning exercises (Tabata style) alternating between 20 seconds of activity and 20 seconds of rest. The exercises focus on strengthening postural muscles, improving rotation, encouraging weight shifting, and initiating movement quickly (the 4 principles of the PWR! concept).\n4. 10-minute break\n5. RGM Block 2 (30 min): cognitive-motor exercises incorporating color, sound, and movement elements (bilateral).\n6. Cool-down (10 min): relaxation, breathing, evaluation.\n\nCognitive component During the sessions, executive functions, attention, and processing speed are challenged and practiced through dual-task situations, pattern recognition, and auditory response tasks.\n\nHome exercises After each session, participants are gi",[43],[54,55],"multimodal therapy","group therapy",[57,62],{"name":58,"role":59,"phone":60,"phoneExt":33,"email":61},"Wim De Wilde, MSc","CONTACT","+32 472 57 58 08","Wim.dewilde@ugent.be",{"name":63,"role":59,"phone":64,"phoneExt":33,"email":65},"Sanne Stegen, dr.","+32 485 50 70 82","sanne.stegen@ugent.be",[67],{"facility":68,"status":69,"city":70,"state":71,"zip":72,"country":73,"countryCode":74,"cosmosGeoPoint":75,"geoPoint":80,"contacts":81},"University Hospital Ghent","RECRUITING","Ghent","Oost-Vlaanderen","9000","Belgium","BE",{"type":76,"coordinates":77},"Point",[78,79],3.71667,51.05,{"lat":79,"lon":78},[82,83,84,87,88],{"name":58,"role":59,"phone":60,"phoneExt":33,"email":61},{"name":63,"role":59,"phone":64,"phoneExt":33,"email":65},{"name":85,"role":86,"phone":33,"phoneExt":33,"email":33},"Sanne Stegen, Dr.","PRINCIPAL_INVESTIGATOR",{"name":58,"role":86,"phone":33,"phoneExt":33,"email":33},{"name":89,"role":86,"phone":33,"phoneExt":33,"email":33},"Dirk Cambier, prof. dr.",{"type":86,"investigatorFullName":91,"investigatorTitle":92,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"Dirk Cambier","Senior Full Professor, Head of Department of Rehabilitation Sciences","100659401","short-term-effects-of-a-multimodal-intervention-with-rgm-on-cognition-in-people-with-parkinsons-disease-100659401",false,"NCT07863219","Short Term Effects of a Multimodal Intervention With RGM on Cognition in People With Parkinson's Disease.","Short-term Effects of an Intervention Consisting of 10 RGM (Ronnie Gardiner Method) Training Sessions on Cognitive Functions in Individuals With Early- to Mid-stage Parkinson's Disease.","Inclusion Criteria:\n\n* diagnosis of idiopathic Parkinson's disease\n* safe, independent mobility and participation (Hoehn and Yahr stages 1-3)\n* a stable dopaminergic medication regimen for at least 4 weeks prior to study participation\n* willingness and ability to participate in a 10-week intervention program\n* willingness to participate in the study (signing of informed consent)\n\nExclusion Criteria:\n\n* Presence of other neurological or severe psychiatric conditions that could interfere with participation or the interpretation of results (e.g., substance use disorder, severe depression, psychosis)\n* Severe visual or hearing impairments that limit the ability to follow group instructions as determined by a physician.\n* Physical limitations that inhibit safe participation in moderate-to-vigorous exercise or group rehabilitation.","ALL","18 Years",{"count":103,"type":104},20,"ESTIMATED","INTERVENTIONAL",[35],"The goal of this clinical trial is to learn if the Ronnie Gardiner Method (RGM) works to improve cognitive functions in adults with Parkinson's disease (early to mid-stage). It will also learn about the secondary effects on speech, mobility, balance, and mood.\n\nThe main questions it aims to answer are:\n\n* Does a 10-week RGM intervention improve cognitive aspects, speech (indirectly through improved breathing), mobility, and balance in participants with Parkinson's disease?\n* How do participants experience the intensity, difficulty, and emotional impact of the RGM sessions?",[109,110,111,112],"Parkinson Disease (PD)","Cognition","Quality of Life","Functional Mobility",[50,54],"2026-10-01",{"date":116,"type":117},"2026-10-07","ACTUAL",{"date":119,"type":117},"2026-08-01",{"date":121,"type":104},"2027-01-30",{"name":5,"class":6},1]