[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654498":3},{"organization":4,"outcomesModule":7,"designInfo":55,"detailedDescription":54,"studyPopulation":58,"armGroups":59,"interventions":69,"overallOfficials":75,"centralContacts":82,"locations":87,"responsibleParty":109,"collaborators":111,"id":114,"slug":115,"hasResults":116,"nctId":117,"briefTitle":118,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":116,"sex":122,"minAge":123,"maxAge":124,"enrollmentInfo":125,"targetDuration":54,"studyType":128,"phases":54,"briefSummary":129,"conditions":130,"keywords":133,"overallStatus":138,"whyStopped":54,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":148},{"fullName":5,"class":6},"The First Affiliated Hospital with Nanjing Medical University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":26,"otherOutcomes":54},[9,13,16,20,23],{"measure":10,"description":11,"timeFrame":12},"Endoscopic reflux esophagitis","Presence and severity of reflux esophagitis assessed by endoscopy using the Los Angeles classification (grades A-D).","1 year after surgery",{"measure":14,"description":15,"timeFrame":12},"Clinically significant reflux symptoms","Reflux symptoms assessed using the GERD-Q questionnaire; a total score greater than 8 is considered clinically significant reflux.",{"measure":17,"description":18,"timeFrame":19},"Change in body mass index","Change in body mass index, measured in kilograms per square meter.","From preoperative baseline to 1 year after surgery",{"measure":21,"description":22,"timeFrame":19},"Change in serum albumin","Change in serum albumin concentration, measured in grams per liter.",{"measure":24,"description":25,"timeFrame":19},"Change in hemoglobin","Change in hemoglobin concentration, measured in grams per liter.",[27,31,35,39,43,47,51],{"measure":28,"description":29,"timeFrame":30},"Perioperative outcomes-Operative time","Operative time in minutes","From surgery through hospital discharge, up to 6 months",{"measure":32,"description":33,"timeFrame":34},"Postoperative complications","Overall complications, severe complications defined as Clavien-Dindo grade IIIa or higher, anastomotic leakage, and anastomotic stricture requiring endoscopic dilation or another intervention.","Within 30 days after surgery",{"measure":36,"description":37,"timeFrame":38},"Overall survival","Time from surgery to death from any cause. Participants alive at last follow-up will be censored.","From the date of surgery until death or last follow-up, up to 12 years",{"measure":40,"description":41,"timeFrame":42},"Disease-free survival","Time from surgery to first local, regional, or distant recurrence or death from any cause. Event-free participants will be censored at last follow-up.","From the date of surgery until recurrence, death, or last follow-up, up to 12 years",{"measure":44,"description":45,"timeFrame":46},"intraoperative blood loss","intraoperative blood loss in milliliters","from surgery to discharge, up to 6 months",{"measure":48,"description":49,"timeFrame":50},"postoperative length of hospital stay","postoperative length of hospital stay in days","from surgery to discharge, up to 6 months.",{"measure":52,"description":53,"timeFrame":46},"conversion to open surgery","conversion to open surgery among patients undergoing minimally invasive surgery (percentage).",null,{"allocation":54,"interventionModel":54,"interventionModelDescription":54,"primaryPurpose":54,"observationalModel":56,"timePerspective":57,"maskingInfo":54},"COHORT","RETROSPECTIVE","Patients treated from June 2015 through June 2025 at either participating center who underwent curative proximal gastrectomy with double-tract reconstruction for proximal gastric adenocarcinoma or Siewert type II\u002FIII adenocarcinoma of the esophagogastric junction.",[60,65],{"label":61,"type":54,"description":62,"interventionNames":63},"Chinese cohort","Patients treated at the First Affiliated Hospital of Nanjing Medical University who underwent proximal gastrectomy with double-tract reconstruction during the study source period.",[64],"Procedure: Proximal gastrectomy with double-tract reconstruction",{"label":66,"type":54,"description":67,"interventionNames":68},"Russian cohort","Patients treated at the Moscow Clinical Scientific Center named after A.S. Loginov who underwent proximal gastrectomy with double-tract reconstruction during the study source period.",[64],[70],{"type":71,"name":72,"description":73,"armGroupLabels":74,"otherNames":54},"PROCEDURE","Proximal gastrectomy with double-tract reconstruction","Curative proximal gastrectomy followed by double-tract reconstruction performed as part of routine clinical care. The study does not assign treatment and retrospectively analyzes existing clinical data.",[61,66],[76,79],{"name":77,"affiliation":5,"role":78},"Hao Xu","PRINCIPAL_INVESTIGATOR",{"name":80,"affiliation":81,"role":78},"Roman Izrailov","Moscow Clinical Scientific Center named after A.S. Loginov",[83],{"name":77,"role":84,"phone":85,"phoneExt":54,"email":86},"CONTACT","+86-138-5153-0117","hxu@njmu.edu.cn",[88,100],{"facility":89,"status":54,"city":90,"state":91,"zip":54,"country":92,"countryCode":93,"cosmosGeoPoint":94,"geoPoint":99,"contacts":54},"First Affiliated Hospital of Nanjing Medical University","Nanjing","Jiangsu","China","CN",{"type":95,"coordinates":96},"Point",[97,98],118.77778,32.06167,{"lat":98,"lon":97},{"facility":81,"status":54,"city":101,"state":54,"zip":54,"country":102,"countryCode":103,"cosmosGeoPoint":104,"geoPoint":108,"contacts":54},"Moscow","Russia","RU",{"type":95,"coordinates":105},[106,107],37.61781,55.75204,{"lat":107,"lon":106},{"type":78,"investigatorFullName":77,"investigatorTitle":110,"investigatorAffiliation":5,"oldNameTitle":54,"oldOrganization":54},"Dr.",[112],{"name":81,"class":113},"UNKNOWN","100654498","sino-russian-comparison-of-outcomes-after-proximal-gastrectomy-with-double-tract-reconstruction-100654498",false,"NCT07800819","Sino-Russian Comparison of Outcomes After Proximal Gastrectomy With Double-Tract Reconstruction","Surgical Outcomes and Long-Term Survival of Proximal Gastrectomy With Double-Tract Reconstruction at High-Volume Centers in Russia and China: A Two-Center Retrospective Analysis","RUSCHI-DTR","Inclusion Criteria:\n\n1. Age 18 to 75 years.\n2. Histologically confirmed gastric adenocarcinoma or Siewert type II\u002FIII adenocarcinoma of the esophagogastric junction.\n3. Underwent proximal gastrectomy with double-tract reconstruction.\n4. Surgery performed with curative intent.\n5. At least one valid postoperative follow-up record containing reflux, nutritional, or complication information.\n6. Clinical, pathological, operative, and follow-up data sufficiently complete for analysis, with less than 20 percent missingness in key variables.\n\nExclusion Criteria:\n\n1. Previous gastric or esophageal surgery, except limited endoscopic treatment such as endoscopic mucosal resection.\n2. Synchronous or metachronous malignancy, except cured non-melanoma skin cancer or cervical carcinoma in situ.\n3. Complete absence of follow-up data.\n4. Double-tract reconstruction not completed or changed to another reconstruction method.\n5. Severe preoperative reflux disease, defined as GERD-Q score greater than 8 with a requirement for long-term medication.","ALL","18 Years","75 Years",{"count":126,"type":127},250,"ESTIMATED","OBSERVATIONAL","This two-center retrospective observational cohort study compares Chinese and Russian patients who underwent curative proximal gastrectomy with double-tract reconstruction for proximal gastric adenocarcinoma or Siewert type II\u002FIII adenocarcinoma of the esophagogastric junction. The study evaluates postoperative reflux, nutritional status, perioperative outcomes, complications, and long-term survival. Propensity score matching will be used to improve comparability between the two cohorts.",[131,132],"Gastric Adenocarcinoma","Adenocarcinoma of the Esophagogastric Junction",[134,135,136,137],"Proximal gastrectomy","Double-tract reconstruction","Reflux esophagitis","Postoperative nutrition","NOT_YET_RECRUITING","2026-08-30",{"date":141,"type":142},"2026-09-02","ACTUAL",{"date":144,"type":127},"2026-08-15",{"date":146,"type":127},"2027-08-15",{"name":5,"class":6},2]