[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568258":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":46,"responsibleParty":70,"collaborators":26,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":75,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":26,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":95,"overallStatus":49,"whyStopped":26,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"University of California, San Diego","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1","EXPERIMENTAL","Participants assigned to the experimental condition.",[13],"Behavioral: Phase Advanced Intervention (PAI)",{"label":15,"type":16,"description":17,"interventionNames":18},"Group 2","ACTIVE_COMPARATOR","Participants assigned to the active comparator condition.",[19],"Behavioral: Phase Delay Intervention (PDI)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Phase Advanced Intervention (PAI)","Phase-advanced restricted sleep (i.e., sleep 9pm-1am only) for 1 night, followed by morning bright white light for 30 min\u002Fday for 2 weeks.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Phase Delay Intervention (PDI)","Phase-delayed restricted sleep (i.e., sleep 3am to 7am only) for 1 night, followed by evening bright white light for 30 min\u002Fday for 2 weeks.",[15],[32],{"name":33,"affiliation":5,"role":34},"Barbara Parry, M.D.","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Jennifer A Perrott, MSW","CONTACT","(407) 619-9441","jperrott@health.ucsd.edu",{"name":42,"role":38,"phone":43,"phoneExt":44,"email":45},"David Sommerfeld, Ph.D.","(407) 966-7703","243609","dsommerfeld@health.ucsd.edu",[47],{"facility":48,"status":49,"city":50,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"University of California San Diego Hillcrest Medical Center","RECRUITING","San Diego","California","92103","United States","US",{"type":56,"coordinates":57},"Point",[58,59],-117.16472,32.71571,{"lat":59,"lon":58},[62,66,69],{"name":63,"role":38,"phone":64,"phoneExt":26,"email":65},"Barbara L Parry, M.D.","(619) 980-1942","bparry@ucsd.edu",{"name":67,"role":38,"phone":68,"phoneExt":26,"email":45},"David H Sommerfeld, Ph.D.","(858) 472-9397",{"name":63,"role":34,"phone":26,"phoneExt":26,"email":26},{"type":34,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Barbara L. Parry, M.D.","Professor of Psychiatry","100568258","sleep-and-light-intervention-sali-for-menopausal-mood-dysfunction-100568258",false,"NCT06678880","Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction","Chronobiological Basis of Depression During the Menopause Transition","SALI","Inclusion Criteria:\n\n* Women aged 45-75 years old\n* Experiencing significant down, sad or hopeless feelings that are affecting their daily life\n* These mood changes started or got worse during the menopause transition\n* Irregular or no menstrual cycle for at least 6 months\n* Non-smoking\n* Located in San Diego County\n\nExclusion Criteria:\n\n* Untreated sleep apnea\n* Migraine headaches that are triggered or worsened by bright light\n* Currently suicidal or psychotic\n* History of bipolar disorder\n* A medical condition or job where fatigue or changes in sleep schedule could be unsafe\n* Planning to start, stop, or change medications in the next 4 months","FEMALE","45 Years","75 Years",{"count":85,"type":86},120,"ESTIMATED","INTERVENTIONAL",[89],"NA","\\*\\*Participants must live in San Diego County\\*\\*\n\nThe purpose of this study is to learn more about an experimental Sleep \\& Light Intervention (SALI) for menopausal mood changes or depression. Researchers want to find out whether adjusting the body's internal clock-which helps regulate sleep, hormones, mood, and energy- can improve symptoms such as depression, poor sleep, and low energy during menopause.",[92,93,94],"Depression","Depression During the Menopausal Transition","Menopausal Depression",[96,97,98,99,100,101],"Menopause","depression","sleep and light intervention","melatonin","circadian rhythm","Chronobiology","2026-08-03",{"date":104,"type":105},"2026-08-05","ACTUAL",{"date":107,"type":105},"2025-03-11",{"date":109,"type":86},"2029-02-28",{"name":5,"class":6},1]