[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100649081":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":10,"locations":27,"responsibleParty":66,"collaborators":68,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":10,"studyType":89,"phases":10,"briefSummary":90,"conditions":91,"keywords":10,"overallStatus":30,"whyStopped":10,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Guardian Research Network, Inc.","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Type 2 Diabetes",null,"SC Medicaid-enrolled Type 2 Diabetes Patients",[13],"Other: Not applicable- observational study",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy Controls","SC Medicaid-enrolled non-T2D Patients",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Not applicable- observational study","Non-interventional biospecimen and data collection study.",[15,9],[24],{"name":25,"affiliation":5,"role":26},"Randy Axelrod, MD","PRINCIPAL_INVESTIGATOR",[28,53],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Clemson Health Clinic at Orangeburg","RECRUITING","Orangeburg","South Carolina","29118","United States","US",{"type":37,"coordinates":38},"Point",[39,40],-80.85565,33.49182,{"lat":40,"lon":39},[43,48,51],{"name":44,"role":45,"phone":46,"phoneExt":10,"email":47},"Katie Poplin","CONTACT","864-656-4503","kpoplin@clemson.edu",{"name":49,"role":45,"phone":46,"phoneExt":10,"email":50},"Jeremy Shields","jnshiel@clemson.edu",{"name":52,"role":26,"phone":10,"phoneExt":10,"email":10},"Peter Carek, MD",{"facility":54,"status":30,"city":55,"state":32,"zip":56,"country":34,"countryCode":35,"cosmosGeoPoint":57,"geoPoint":61,"contacts":62},"Clemson Health Clinic at Walhalla","Walhalla","29691",{"type":37,"coordinates":58},[59,60],-83.06404,34.76482,{"lat":60,"lon":59},[63,64,65],{"name":44,"role":45,"phone":46,"phoneExt":10,"email":47},{"name":49,"role":45,"phone":46,"phoneExt":10,"email":50},{"name":52,"role":26,"phone":10,"phoneExt":10,"email":10},{"type":67,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[69,72],{"name":70,"class":71},"South Carolina Department of Health and Human Services","UNKNOWN",{"name":73,"class":6},"Spartanburg Regional Healthcare System","100649081","specimen-and-data-collection-in-south-carolina-medicaid-enrolled-patients-with-type-2-diabetes-t2d-and-metabolically-healthy-controls-100649081",false,"NCT07731399","Specimen and Data Collection in South Carolina Medicaid-Enrolled Patients With Type 2 Diabetes (T2D) and Metabolically Healthy Controls","An Observational Clinical Research Study Assembling and Analyzing Highly Complex, Multi-dimensional Molecular and Clinical Data With a Focus on High-risk Diabetes Patients in South Carolina, in Support of the Biomedical Research Initiative for Scientific Knowledge (BRISK)","BRISK 2","INCLUSION CRITERIA:\n\nAll Participants:\n\n* 40 to 70 years of age (inclusive) at enrollment\n* Enrolled as Medicaid recipients\n* Ability to provide informed consent and authorization for release of relevant protected health information or personal data\n* Ability to provide a blood sample(s) of up to 70 mL and other required biospecimens, including genetic samples.\n\nT2D Group:\n\n• Current diagnosis of Type 2 diabetes OR a blood level of hemoglobin A1c equal to or greater than 6.5% at any time within the past 12 months\n\nControl Group:\n\n* Blood level of hemoglobin A1c less than or equal to 5.6% at time of enrollment\n* No diagnosis of Type 2 diabetes\n\nEXCLUSION CRITERIA:\n\n* Pregnancy at time of enrollment (by self-report of pregnancy status)\n* Lack of fluency in spoken and written English\n* Type 1 diabetes or any other type of diabetes besides Type 2 diabetes\n* Active cancer diagnosis or cancer that achieved complete remission within three (3) years prior to enrollment, other than non-melanoma skin cancer (e.g. malignant basal cell neoplasm of skin and\u002For squamous cell carcinoma of skin)\n* Major Adverse Cardiovascular Events within two (2) years prior to enrollment\n* Chronic Obstructive Pulmonary Disease\n* Cognitive impairment or neurodegenerative diseases (e.g., Alzheimer's disease, dementia, multiple sclerosis, Parkinson's disease, etc.)\n* Pancreatitis or other diseases of the pancreas (besides diabetes)\n* The participant is, in the opinion of the investigator, unlikely to be able to complete all study requirements",true,"ALL","40 Years","70 Years",{"count":87,"type":88},1200,"ESTIMATED","OBSERVATIONAL","The primary purpose of this study is to use multiomic data in combination with clinical assessments, electronic health records, cognitive and mood assessments, wearable technologies and lifestyle\u002Fbehavioral data to identify data elements or combinations of data elements with strong positive or negative correlation to CKD diagnosis and\u002For progression in Type 2 Diabetes (T2D) patients. Achieving this aim will allow researchers and physicians to significantly improve the prediction of health trajectories of and formulate novel strategies to potentially prevent, treat or reverse T2D. South Carolina Medicaid-enrolled patients diagnosed with T2D and a smaller subset of non-T2D SC Medicaid patients may participate in this study. Participants who complete required procedures will be compensated for their time and transportation, may keep their study-provided Fitbit device to help maintain their healthcare improvement journey, and will have a personal Certified Diabetes Educator to consult and assist with managing their diabetes diagnosis.",[9,92],"Healthy (Controls)","2026-08-17",{"date":95,"type":96},"2026-08-18","ACTUAL",{"date":98,"type":88},"2026-08",{"date":100,"type":88},"2029-10",{"name":5,"class":6},2]