[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576621":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":11,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":11,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":11,"enrollmentInfo":63,"targetDuration":11,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":11,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Beijing Tiantan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PRF group","EXPERIMENTAL",null,[13],"Procedure: PRF",{"label":15,"type":16,"description":11,"interventionNames":17},"Nerve Block Group","ACTIVE_COMPARATOR",[18],"Procedure: NB",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"PROCEDURE","PRF","After the puncture needle reached the sphenopalatine ganglion (SPG), patients in the PRF group received PRF treatment in automatic mode for 360 s, at a maximum of 42°C, pulse frequency of 2 Hz, and pulse width of 20 ms.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"NB","After the puncture needle reached the sphenopalatine ganglion (SPG), patients in the NB group received nerve block with a mixture of 40 mg of triamcinolone and 2 ml of 0.75% bupivacaine with 2 ml of normal saline and 1:100000 epinephrine.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Fang Luo","CONTACT","59976661","13611326978@163.com",[36],{"facility":31,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"RECRUITING","Beijing","Beijing Municipality","100070","China","CN",{"type":44,"coordinates":45},"Point",[46,47],116.39723,39.9075,{"lat":47,"lon":46},[50],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},{"type":52,"investigatorFullName":31,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Director of Department of Pain Management","100576621","spg-pulsed-radiofrequency-for-chronic-cluster-headache-100576621",false,"NCT06787677","SPG Pulsed Radiofrequency for Chronic Cluster Headache","The Efficacy and Safety of Sphenopalatine Ganglion Pulsed Radiofrequency Treatment for Chronic Cluster Headache","Inclusion Criteria:\n\n* Chronic cluster headache;\n* At least four attacks per week;\n* Minimum age of 18 years;\n* Non-response to verapamil and lithium treatment in the past, intolerance, or contraindication to verapamil and lithium, along with non-response, intolerance, or contraindica-tion to topiramate, or gabapentin.\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding;\n* Presence of cardiac pacemaker or other neuromodulatory devices;\n* Pyschiatric and cognitive disorders;\n* Serious drug habituation or overuse of acute-headache medication;\n* History of stroke or intracranial aneurysm, or at risk for serious or acute cardiovascular events;\n* Infection at the puncture site;\n* Previous history of invasive treatments such as sphenopalatine ganglion radiofrequency thermocoagulation and chemical destruction.","ALL","18 Years",{"count":64,"type":65},108,"ESTIMATED","INTERVENTIONAL",[68],"NA","Cluster headache (CH) is a devastating disorder characterized by ipsilateral headache and associated trigeminal autonomic symptoms, with a yearly prevalence of 0.1%. There is a huge clinically unmet demand for an effective therapeutic method for CH. Previous evidences indicate that pulse radiofrequency (PRF) targeting the sphenopalatine ganglion (SPG) is a safe, minimally invasive, effective treatment for CH. This randomized, controlled trial aimed to establish the safety and efficacy of SPG PRF for patients with chronic CH.",[71],"Headache, Cluster","2025-01-23",{"date":74,"type":75},"2025-01-27","ACTUAL",{"date":77,"type":75},"2025-01-24",{"date":79,"type":65},"2030-12-31",{"name":5,"class":6},1]