[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100658303":3},{"organization":4,"outcomesModule":7,"designInfo":28,"detailedDescription":27,"studyPopulation":30,"armGroups":31,"interventions":27,"overallOfficials":27,"centralContacts":36,"locations":42,"responsibleParty":57,"collaborators":27,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":27,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":27,"studyType":75,"phases":27,"briefSummary":76,"conditions":77,"keywords":82,"overallStatus":45,"whyStopped":27,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Mustafa Kemal University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":27},[9],{"measure":10,"description":11,"timeFrame":12},"Spinal Mobility","Assessed through Modified-Modified Schober Test (cm), Tragus-to-Wall Distance (cm), Occiput-to-Wall Distance (cm), and Intermalleolar Distance (cm)","Baseline (measured once during a single evaluation session)",[14,18,21,24],{"measure":15,"description":16,"timeFrame":17},"Axial Rigidity","Assessed using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part III, item 3.3 (Rigidity). Scores range from 0 (normal) to 4 (severe)","Baseline (single evaluation session)",{"measure":19,"description":20,"timeFrame":17},"Kinesiophobia Level","Evaluated using the Tampa Scale for Kinesiophobia (TSK; 17 items, 4-point Likert scale, total score range: 17-68, where higher scores indicate greater fear of movement)",{"measure":22,"description":23,"timeFrame":17},"Postural Alignment and Forward Head Posture","Assessed via MDS-UPDRS item 3.13 (Posture, score 0-4) and Craniovertebral Angle measurement using a goniometer (degrees)",{"measure":25,"description":26,"timeFrame":17},"Temporomandibular Joint Range of Motion","Maximum mouth opening, protrusion, retrusion, and bilateral lateral excursion measured in millimeters using a millimeter ruler.",null,{"allocation":27,"interventionModel":27,"interventionModelDescription":27,"primaryPurpose":27,"observationalModel":6,"timePerspective":29,"maskingInfo":27},"CROSS_SECTIONAL","The study population consists of individuals aged 40-75 years diagnosed with Parkinson's disease (Modified Hoehn \\& Yahr stages 1.5-4) who are admitted to the Neurology Outpatient Clinic of Hatay Mustafa Kemal University Research and Training Hospital.",[32,34],{"label":33,"type":27,"description":27,"interventionNames":27},"Parkinson's Disease with TMD",{"label":35,"type":27,"description":27,"interventionNames":27},"Parkinson's Disease without TMD",[37],{"name":38,"role":39,"phone":40,"phoneExt":27,"email":41},"derya yavuz demiray","CONTACT","+90 5305146831","deryayavuz149@gmail.com",[43],{"facility":44,"status":45,"city":46,"state":27,"zip":27,"country":47,"countryCode":27,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Hatay Mustafa Kemal Universty","RECRUITING","Hatay","Turkey (Türkiye)",{"type":49,"coordinates":50},"Point",[51,52],27.10486,38.40227,{"lat":52,"lon":51},[55],{"name":38,"role":39,"phone":56,"phoneExt":27,"email":41},"+905305146831",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":27,"oldOrganization":27},"PRINCIPAL_INVESTIGATOR","İsmail KARA","Research Assistant","100658303","spinal-mobility-rigidity-and-kinesiophobia-in-pd-and-tmd-100658303",false,"NCT07850674","Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD","A Comparative Study of Spinal Mobility, Axial Rigidity, and Kinesiophobia Between Parkinson's Disease Patients With and Without Temporomandibular Disorders","Inclusion Criteria:\n\n* Diagnosed with Parkinson's disease\n* Modified Hoehn \\& Yahr stages 1.5 to 4\n* Mini-Mental State Examination (MMSE) score ≥ 24\n* Evaluated during the medication \"ON\" state\n\nExclusion Criteria:\n\n* History of cervical, lumbar, maxillofacial, or temporomandibular joint surgery -Acute orthopedic or severe rheumatologic disease (e.g., advanced ankylosing spondylitis)\n* Additional comorbid neurological disorders (e.g., stroke, multiple sclerosis)\n* Complete edentulism or severe disruption of oral anatomy\n* Ongoing acute dental pain\n* Pregnancy or suspected pregnancy\n* Severe psychiatric disorders",true,"ALL","35 Years","75 Years",{"count":73,"type":74},60,"ESTIMATED","OBSERVATIONAL","Axial rigidity and loss of spinal mobility commonly observed in Parkinson's disease (PD) lead to postural deformities and substantial reductions in trunk flexibility. This condition can impair the biomechanics of the craniocervical and lumbopelvic kinetic chain, potentially exerting a negative impact on temporomandibular joint (TMJ) functions. In this context, the planned study aims to determine whether differences exist in spinal mobility, axial rigidity, and kinesiophobia levels between individuals with PD with and without Temporomandibular Disorders (TMD), and to investigate whether a biomechanical relationship exists between TMD and spinal mobility, axial rigidity, and kinesiophobia levels in this population.\n\nThe study will be conducted face-to-face at the Neurology Outpatient Clinic of Hatay Mustafa Kemal University Research and Training Hospital. Individuals aged 40-75 years, diagnosed with PD, staged between 1.5 and 4 according to the Hoehn and Yahr Scale, with a Mini-Mental State Examination score of 24 or higher (MMSE ≥ 24), and in the \"ON\" state during the evaluation will be included. Individuals with a history of cervical, lumbar, maxillofacial, or TMJ surgery that could directly affect spinal mobility and posture; acute orthopedic or rheumatologic disorders that would preclude testing (e.g., advanced Ankylosing Spondylitis); comorbid neurological conditions (e.g., stroke, multiple sclerosis); complete edentulism or severe disruption of oral anatomy; active toothache; pregnancy or suspected pregnancy; and severe psychiatric disorders will be excluded. Written informed consent will be obtained from all participants, and the study will be conducted on a voluntary basis. All data will remain confidential and be utilized solely for scientific purposes.\n\nIn this cross-sectional study, evaluations will be carried out in a single session for each participant. Following the recording of demographic and clinical characteristics, the presence of TMD will be assessed using the Fonseca Anamnestic Index, jaw range of motion with a millimeter ruler, and spinal mobility using the modified-modified Schober test, tragus-to-wall distance, intermalleolar distance, and occiput-to-wall distance measurements. Axial rigidity will be evaluated using item 3.3 (Rigidity) of the Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS), posture will be assessed using MDS-UPDRS item 3.13 (Posture) alongside craniovertebral angle measurement, and kinesiophobia will be assessed via the Tampa Scale for Kinesiophobia.\n\nThe resulting findings are expected to contribute to understanding the impact of spinal mobility, axial rigidity, and kinesiophobia on the temporomandibular system in PD, offering valuable clinical guidance for assessment, physiotherapy, and multidisciplinary neurological rehabilitation pathways.",[78,79,80,81],"PARKINSON DISEASE (Disorder)","Rigidity","Temporomandibular Disorders (TMDs)","Mobility",[83,84,85,86],"parkınson","rigidity","mobility","temporomandibular disorders","2026-09-30",{"date":89,"type":90},"2026-10-05","ACTUAL",{"date":92,"type":90},"2026-09-23",{"date":94,"type":74},"2026-12-30",{"name":5,"class":6},1]