[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100532064":3},{"organization":4,"outcomesModule":7,"designInfo":54,"detailedDescription":66,"studyPopulation":16,"armGroups":67,"interventions":99,"overallOfficials":16,"centralContacts":125,"locations":131,"responsibleParty":501,"collaborators":503,"id":512,"slug":513,"hasResults":514,"nctId":515,"briefTitle":516,"officialTitle":517,"acronym":16,"eligibilityCriteria":518,"healthyVolunteers":514,"sex":519,"minAge":520,"maxAge":16,"enrollmentInfo":521,"targetDuration":16,"studyType":524,"phases":525,"briefSummary":527,"conditions":528,"keywords":16,"overallStatus":134,"whyStopped":16,"lastUpdateSubmitDate":533,"lastUpdatePostDateStruct":534,"startDateStruct":537,"completionDateStruct":539,"leadSponsor":541,"locationsCount":542},{"fullName":5,"class":6},"Region Skane","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":16,"otherOutcomes":17},[9,13],{"measure":10,"description":11,"timeFrame":12},"Montreal Cognitive Assessment (MoCA)","Cognitive function for out of hospital cardiac arrest survivors. Score range. Higher scores=better cognition","6 months",{"measure":14,"description":15,"timeFrame":12},"Zarit Burden Interview (ZBI)","Caregiver burden for caregivers to out of hospital cardiac arrest survivors. Score range 0-88. Higher scores= worse indicating more caregiver burden",null,[18,22,25,28,31,35,38,41,45,48,51],{"measure":19,"description":20,"timeFrame":21},"Symbol Digit Modalities Test (SDMT)","Processing speed. For out of hospital cardiac arrest survivors. Scores presented as age and education adjusted z-scores. Higher scores=better","6 and 12 months",{"measure":23,"description":24,"timeFrame":21},"Hospital Anxiety and Depression Scale (HADS)","Symptoms of anxiety and depression. For both out of hospital cardiac arrest survivors and caregivers. Score range 0-21 for anxiety and depression respectively. Higher scores=worse and incerased symptoms of anxiety and depression",{"measure":26,"description":27,"timeFrame":21},"Post Posttraumatic Stress Disorders Checklist updated for DSM-5 (PCL-5)","Symptoms of posttraumatic stress. For both out of hospital cardiac arrest survivors and caregivers. Score range 0-80. Higher scores=worse indicating increased symptoms of PTSD",{"measure":29,"description":30,"timeFrame":21},"Modified Fatigue Impact Scale (MFIS)","Impact of fatigue. For out of hospital cardiac arrest survivors. Score range 0-84. Higher scores= worse indicating more problems with impact of fatigue",{"measure":32,"description":33,"timeFrame":34},"modified Rankin Scale (mRS)","Functional outcome. For out of hospital cardiac arrest survivors. Score range 0-6. Higher scores= worse indicating a poorer functional outcome","12 months",{"measure":36,"description":37,"timeFrame":21},"World Health Organization Disability Assessment (WHODAS) 2.0","Disability. For both out of hospital cardiac arrest survivors and caregivers. 36 item version score range 0-100. 12 item version score range 0-48. Higher scores=worse indicating more disability",{"measure":39,"description":40,"timeFrame":21},"Return to work","Questions about work prior to cardiac arrest and at time of follow up. For both out of hospital cardiac arrest survivors and caregivers. Categorical item",{"measure":42,"description":43,"timeFrame":44},"EuroQol health survey 5 dimensions 5 levels response version (EQ-5D-5L)","Health related quality of life. For both out of hospital cardiac arrest survivors and caregivers. For EQ dimensions score range 1-5 and higher scores=worse indicating more health problems. For EQ VAS score range is 0-100 with higher scores= better and representing higher satisfaction with overall health","12 months for out of hospital cardiac arrest survivors. 6 and 12 months for caregiver",{"measure":46,"description":47,"timeFrame":21},"Life satisfaction visual analogue scale from the World Value Survey","Life satisfaction. For both out of hospital cardiac arrest survivors and caregivers. Score range 1-10. Higher scores=better indicating better life satisfaction",{"measure":49,"description":50,"timeFrame":21},"Timed Stands Test (TST)","Lower extremity strength. For out of hospital cardiac arrest survivors. Raw score adjusted for gender and age and categorized as normal, problems or unable.",{"measure":52,"description":53,"timeFrame":21},"Jamar hand grip dynamometer","Upper extremity strength. For out of hospital cardiac arrest survivors. Raw scores age and gender adjusted and categorized as normal, problems or unable.",{"allocation":55,"interventionModel":56,"interventionModelDescription":57,"primaryPurpose":58,"observationalModel":16,"timePerspective":16,"maskingInfo":59},"RANDOMIZED","FACTORIAL","2X2X2 factorial., with all participants taking part in each factor","TREATMENT",{"masking":60,"maskingDescription":61,"whoMasked":62},"TRIPLE","Participants (out of hospital cardiac arrest survivors and caregivers) will be blinded. Assessors of neurological prognosis will be blinded. Outcome assessors and investigators will be blinded.",[63,64,65],"PARTICIPANT","INVESTIGATOR","OUTCOMES_ASSESSOR","This extended follow-up substudy is incorporated into the multi-center, international, factorial randomized Sedation, Temperature and Pressure after Cardiac Arrest and Resuscitation -STEPCARE trial (Clinical trials identifier:NCT05564754) were out of hospital cardiac arrest participants will be randomized to different targets of sedation, temperature, and MAP management.\n\nOnly selected STEPCARE sites will participate in this extended follow-up substudy. At the extended follow up participating sites all out of hospital cardiac arrest participants randomized in the STEPCARE trial, who survive and provide consent, will be eligible to participate in this substudy, with no further inclusion or exclusion criteria.The extended follow-up substudy is estimated to enroll approximately 600 post OHCA survivors. One nominated caregiver per post OHCA survivor will be invited to be included in the study.\n\nParticipants will be followed up at 6 and 12 months.\n\nThe primary outcome for this extended follow up substudy is cognitive function at 6 months for the out of hospital cardiac arrest survivors andCaregiver burden at 6 months for the caregivers.",[68,75,79,83,86,90,93,96],{"label":69,"type":70,"description":16,"interventionNames":71},"Sedation, temperature device and high MAP","ACTIVE_COMPARATOR",[72,73,74],"Device: Feed back controlled temperature device","Other: High MAP","Other: Deep sedation",{"label":76,"type":70,"description":16,"interventionNames":77},"Sedation, no temperature device and high MAP",[73,74,78],"Other: Fever control without a device",{"label":80,"type":70,"description":16,"interventionNames":81},"Sedation, temperature device and low MAP",[72,74,82],"Other: Low MAP",{"label":84,"type":70,"description":16,"interventionNames":85},"Sedation, no temperature device, and low MAP",[74,78,82],{"label":87,"type":70,"description":16,"interventionNames":88},"Minimal sedation, temperature device, and high MAP",[72,73,89],"Other: Minimal sedation",{"label":91,"type":70,"description":16,"interventionNames":92},"Minimal sedation, no temperature device and high MAP",[73,78,89],{"label":94,"type":70,"description":16,"interventionNames":95},"Minimal sedation, temperature device and low MAP",[72,82,89],{"label":97,"type":70,"description":16,"interventionNames":98},"Minimal sedation, no temperature device and low MAP",[78,82,89],[100,105,109,113,117,121],{"type":101,"name":102,"description":103,"armGroupLabels":104,"otherNames":16},"DEVICE","Feed back controlled temperature device","If core temperature exceeds 37.7 degrees celsius a feedback controlled-device will be used at set to 37.5 degrees celsius",[94,87,69,80],{"type":6,"name":106,"description":107,"armGroupLabels":108,"otherNames":16},"High MAP","A mean arterial blood pressure (MAP) of \\>85mmHg will be used. Vasopressors will be titrated to this target during 36 hours",[91,87,76,69],{"type":6,"name":110,"description":111,"armGroupLabels":112,"otherNames":16},"Deep sedation","Deep sedation for at least 36 hours",[76,84,69,80],{"type":6,"name":114,"description":115,"armGroupLabels":116,"otherNames":16},"Fever control without a device","Management of fever in the intensive care unit without a device",[91,97,76,84],{"type":6,"name":118,"description":119,"armGroupLabels":120,"otherNames":16},"Low MAP","A mean arterial blood pressure (MAP) of \\>65mmHG will be used. Vasopressors will be titrated to this target during 36 hours",[97,94,84,80],{"type":6,"name":122,"description":123,"armGroupLabels":124,"otherNames":16},"Minimal sedation","A strategy of minimal sedation in the intensive care unit, used only as needed to facilitate transport, imaging and invasive procedures",[91,97,94,87],[126],{"name":127,"role":128,"phone":129,"phoneExt":16,"email":130},"Gisela Lilja, PhD","CONTACT","+4646176393","gisela.lilja@med.lu.se",[132,147,158,168,179,187,198,206,216,226,237,250,258,269,282,293,301,313,323,331,341,351,361,372,387,398,409,420,431,444,455,468,479,490],{"facility":133,"status":134,"city":135,"state":16,"zip":16,"country":136,"countryCode":137,"cosmosGeoPoint":138,"geoPoint":143,"contacts":144},"Princess Alexandra Hospital","RECRUITING","Brisbane","Australia","AU",{"type":139,"coordinates":140},"Point",[141,142],153.02809,-27.46794,{"lat":142,"lon":141},[145],{"name":146,"role":128,"phone":16,"phoneExt":16,"email":16},"James Walsham",{"facility":148,"status":134,"city":149,"state":16,"zip":16,"country":136,"countryCode":137,"cosmosGeoPoint":150,"geoPoint":154,"contacts":155},"The Sutherland Hospital","Caringbah",{"type":139,"coordinates":151},[152,153],151.12468,-34.03534,{"lat":153,"lon":152},[156],{"name":157,"role":128,"phone":16,"phoneExt":16,"email":16},"Frances Bass",{"facility":159,"status":134,"city":160,"state":16,"zip":16,"country":136,"countryCode":137,"cosmosGeoPoint":161,"geoPoint":165,"contacts":166},"The Prince Charles Hospital","Chermside",{"type":139,"coordinates":162},[163,164],153.03062,-27.38472,{"lat":164,"lon":163},[167],{"name":157,"role":128,"phone":16,"phoneExt":16,"email":16},{"facility":169,"status":134,"city":170,"state":16,"zip":16,"country":136,"countryCode":137,"cosmosGeoPoint":171,"geoPoint":175,"contacts":176},"Nepean hospital","Kingswood",{"type":139,"coordinates":172},[173,174],150.72346,-33.75614,{"lat":174,"lon":173},[177],{"name":178,"role":128,"phone":16,"phoneExt":16,"email":16},"Ian Seppelt, Dr",{"facility":180,"status":134,"city":181,"state":16,"zip":16,"country":136,"countryCode":137,"cosmosGeoPoint":182,"geoPoint":186,"contacts":16},"St George hospital","Kogarah",{"type":139,"coordinates":183},[184,185],151.13564,-33.9681,{"lat":185,"lon":184},{"facility":188,"status":134,"city":189,"state":16,"zip":16,"country":136,"countryCode":137,"cosmosGeoPoint":190,"geoPoint":194,"contacts":195},"Liverpool hospital","Liverpool",{"type":139,"coordinates":191},[192,193],150.92588,-33.91938,{"lat":193,"lon":192},[196],{"name":197,"role":128,"phone":16,"phoneExt":16,"email":16},"Anthony Stewart, Dr",{"facility":199,"status":134,"city":200,"state":16,"zip":16,"country":136,"countryCode":137,"cosmosGeoPoint":201,"geoPoint":205,"contacts":16},"Austin hospital","Melbourne",{"type":139,"coordinates":202},[203,204],144.96332,-37.814,{"lat":204,"lon":203},{"facility":207,"status":134,"city":208,"state":16,"zip":16,"country":136,"countryCode":137,"cosmosGeoPoint":209,"geoPoint":213,"contacts":214},"Royal North Shore Hospital","Sydney",{"type":139,"coordinates":210},[211,212],151.20732,-33.86785,{"lat":212,"lon":211},[215],{"name":157,"role":128,"phone":16,"phoneExt":16,"email":16},{"facility":217,"status":134,"city":218,"state":16,"zip":16,"country":219,"countryCode":220,"cosmosGeoPoint":221,"geoPoint":225,"contacts":16},"Ziekenhuis Oost Limburg","Genk","Belgium","BE",{"type":139,"coordinates":222},[223,224],5.50082,50.965,{"lat":224,"lon":223},{"facility":227,"status":134,"city":228,"state":16,"zip":16,"country":219,"countryCode":220,"cosmosGeoPoint":229,"geoPoint":233,"contacts":234},"Ghent university hospital","Ghent",{"type":139,"coordinates":230},[231,232],3.71667,51.05,{"lat":232,"lon":231},[235],{"name":236,"role":128,"phone":16,"phoneExt":16,"email":16},"Patrick Druwve",{"facility":238,"status":134,"city":239,"state":16,"zip":16,"country":240,"countryCode":241,"cosmosGeoPoint":242,"geoPoint":246,"contacts":247},"Helsinki Helsingfors university central hospital","Helsinki","Finland","FI",{"type":139,"coordinates":243},[244,245],24.93545,60.16952,{"lat":245,"lon":244},[248],{"name":249,"role":128,"phone":16,"phoneExt":16,"email":16},"Marjaana Tiainen",{"facility":251,"status":134,"city":252,"state":16,"zip":16,"country":240,"countryCode":241,"cosmosGeoPoint":253,"geoPoint":257,"contacts":16},"Jorvi hospital","Jorvi",{"type":139,"coordinates":254},[255,256],24.68894,60.22204,{"lat":256,"lon":255},{"facility":259,"status":134,"city":260,"state":16,"zip":16,"country":240,"countryCode":241,"cosmosGeoPoint":261,"geoPoint":265,"contacts":266},"Tampere university hospital","Tampere",{"type":139,"coordinates":262},[263,264],23.78712,61.49911,{"lat":264,"lon":263},[267],{"name":268,"role":128,"phone":16,"phoneExt":16,"email":16},"Joonas Tirkkonen",{"facility":270,"status":134,"city":271,"state":16,"zip":16,"country":272,"countryCode":273,"cosmosGeoPoint":274,"geoPoint":278,"contacts":279},"Charite university hospital","Berlin","Germany","DE",{"type":139,"coordinates":275},[276,277],13.41053,52.52437,{"lat":277,"lon":276},[280],{"name":281,"role":128,"phone":16,"phoneExt":16,"email":16},"Christoph Leithner",{"facility":283,"status":134,"city":284,"state":16,"zip":16,"country":272,"countryCode":273,"cosmosGeoPoint":285,"geoPoint":289,"contacts":290},"Universitäres Herzzentrum Lübeck Universitätsklinikum Schleswig-Holstein","Lübeck",{"type":139,"coordinates":286},[287,288],10.68729,53.86893,{"lat":288,"lon":287},[291],{"name":292,"role":128,"phone":16,"phoneExt":16,"email":16},"Tobias Graf",{"facility":294,"status":134,"city":295,"state":16,"zip":16,"country":272,"countryCode":273,"cosmosGeoPoint":296,"geoPoint":300,"contacts":16},"Tubingen university hospital","Tübingen",{"type":139,"coordinates":297},[298,299],9.05222,48.52266,{"lat":299,"lon":298},{"facility":302,"status":134,"city":303,"state":16,"zip":16,"country":303,"countryCode":304,"cosmosGeoPoint":305,"geoPoint":309,"contacts":310},"Centre Hospitalier de Luxembourg","Luxembourg","LU",{"type":139,"coordinates":306},[307,308],6.13268,49.60982,{"lat":308,"lon":307},[311],{"name":312,"role":128,"phone":16,"phoneExt":16,"email":16},"Pascal Stammet, MD, PhD",{"facility":314,"status":134,"city":315,"state":16,"zip":16,"country":316,"countryCode":317,"cosmosGeoPoint":318,"geoPoint":322,"contacts":16},"Auckland city hospital","Auckland","New Zealand","NZ",{"type":139,"coordinates":319},[320,321],174.76349,-36.84853,{"lat":321,"lon":320},{"facility":324,"status":134,"city":315,"state":16,"zip":16,"country":316,"countryCode":317,"cosmosGeoPoint":325,"geoPoint":327,"contacts":328},"Middlemore hospital",{"type":139,"coordinates":326},[320,321],{"lat":321,"lon":320},[329],{"name":330,"role":128,"phone":16,"phoneExt":16,"email":16},"Paul Young",{"facility":332,"status":134,"city":333,"state":16,"zip":16,"country":316,"countryCode":317,"cosmosGeoPoint":334,"geoPoint":338,"contacts":339},"Christchurch hospital","Christchurch",{"type":139,"coordinates":335},[336,337],172.63333,-43.53333,{"lat":337,"lon":336},[340],{"name":330,"role":128,"phone":16,"phoneExt":16,"email":16},{"facility":342,"status":134,"city":343,"state":16,"zip":16,"country":316,"countryCode":317,"cosmosGeoPoint":344,"geoPoint":348,"contacts":349},"Wellington hospital","Wellington",{"type":139,"coordinates":345},[346,347],174.77557,-41.28664,{"lat":347,"lon":346},[350],{"name":330,"role":128,"phone":16,"phoneExt":16,"email":16},{"facility":352,"status":134,"city":353,"state":16,"zip":16,"country":354,"countryCode":355,"cosmosGeoPoint":356,"geoPoint":360,"contacts":16},"Sorlandet hospital","Arendal","Norway","NO",{"type":139,"coordinates":357},[358,359],8.77253,58.46151,{"lat":359,"lon":358},{"facility":362,"status":134,"city":363,"state":16,"zip":16,"country":354,"countryCode":355,"cosmosGeoPoint":364,"geoPoint":368,"contacts":369},"Oslo university hospital Rikshospitalet","Oslo",{"type":139,"coordinates":365},[366,367],10.74609,59.91273,{"lat":367,"lon":366},[370],{"name":371,"role":128,"phone":16,"phoneExt":16,"email":16},"Louis Romundstad",{"facility":373,"status":134,"city":374,"state":16,"zip":16,"country":375,"countryCode":376,"cosmosGeoPoint":377,"geoPoint":381,"contacts":382},"Sahlgrenska university hospital","Gothenburg","Sweden","SE",{"type":139,"coordinates":378},[379,380],11.96679,57.70716,{"lat":380,"lon":379},[383,385],{"name":384,"role":128,"phone":16,"phoneExt":16,"email":16},"Jonathan Oras",{"name":386,"role":128,"phone":16,"phoneExt":16,"email":16},"Andreas Lundin",{"facility":388,"status":134,"city":389,"state":16,"zip":16,"country":375,"countryCode":376,"cosmosGeoPoint":390,"geoPoint":394,"contacts":395},"Hallands hospital","Hålland",{"type":139,"coordinates":391},[392,393],13.31667,63.31667,{"lat":393,"lon":392},[396],{"name":397,"role":128,"phone":16,"phoneExt":16,"email":16},"Johan Unden, MD PhD",{"facility":399,"status":134,"city":400,"state":16,"zip":16,"country":375,"countryCode":376,"cosmosGeoPoint":401,"geoPoint":405,"contacts":406},"Helsingborg hospital","Helsingborg",{"type":139,"coordinates":402},[403,404],12.69437,56.04673,{"lat":404,"lon":403},[407],{"name":408,"role":128,"phone":16,"phoneExt":16,"email":16},"Jesper Johnsson, MD, PhD",{"facility":410,"status":134,"city":411,"state":16,"zip":16,"country":375,"countryCode":376,"cosmosGeoPoint":412,"geoPoint":416,"contacts":417},"Skåne university hospital","Lund",{"type":139,"coordinates":413},[414,415],13.19321,55.70584,{"lat":415,"lon":414},[418],{"name":419,"role":128,"phone":16,"phoneExt":16,"email":16},"Anna Lybeck, MD, PhD",{"facility":421,"status":134,"city":422,"state":16,"zip":16,"country":375,"countryCode":376,"cosmosGeoPoint":423,"geoPoint":427,"contacts":428},"Skåne university hopsital","Malmö",{"type":139,"coordinates":424},[425,426],13.00073,55.60587,{"lat":426,"lon":425},[429],{"name":430,"role":128,"phone":16,"phoneExt":16,"email":16},"Joachim During, MD, PhD",{"facility":432,"status":134,"city":433,"state":16,"zip":16,"country":434,"countryCode":435,"cosmosGeoPoint":436,"geoPoint":440,"contacts":441},"Bern university hospital","Bern","Switzerland","CH",{"type":139,"coordinates":437},[438,439],7.44744,46.94809,{"lat":439,"lon":438},[442],{"name":443,"role":128,"phone":16,"phoneExt":16,"email":16},"Manuela Itens",{"facility":445,"status":134,"city":446,"state":16,"zip":16,"country":434,"countryCode":435,"cosmosGeoPoint":447,"geoPoint":451,"contacts":452},"Kantonsspital St. Gallen","Sankt Gallen",{"type":139,"coordinates":448},[449,450],9.37477,47.42391,{"lat":450,"lon":449},[453],{"name":454,"role":128,"phone":16,"phoneExt":16,"email":16},"Claudia Schrag",{"facility":456,"status":134,"city":457,"state":16,"zip":16,"country":458,"countryCode":459,"cosmosGeoPoint":460,"geoPoint":464,"contacts":465},"The Essex Cardiothoracic Centre","Basildon","United Kingdom","UK",{"type":139,"coordinates":461},[462,463],0.45782,51.56844,{"lat":463,"lon":462},[466],{"name":467,"role":128,"phone":16,"phoneExt":16,"email":16},"Thomas Keeble",{"facility":469,"status":134,"city":470,"state":16,"zip":16,"country":458,"countryCode":459,"cosmosGeoPoint":471,"geoPoint":475,"contacts":476},"Bristol Royal Infirmary","Bristol",{"type":139,"coordinates":472},[473,474],-2.59665,51.45523,{"lat":474,"lon":473},[477],{"name":478,"role":128,"phone":16,"phoneExt":16,"email":16},"Matthew Thomas",{"facility":480,"status":134,"city":481,"state":16,"zip":16,"country":458,"countryCode":459,"cosmosGeoPoint":482,"geoPoint":486,"contacts":487},"University hospital of Wales","Cardiff",{"type":139,"coordinates":483},[484,485],-3.18,51.48,{"lat":485,"lon":484},[488],{"name":489,"role":128,"phone":16,"phoneExt":16,"email":16},"Matt Wise",{"facility":491,"status":134,"city":492,"state":16,"zip":16,"country":458,"countryCode":459,"cosmosGeoPoint":493,"geoPoint":497,"contacts":498},"St Bartholomew's hospital","London",{"type":139,"coordinates":494},[495,496],-0.12574,51.50853,{"lat":496,"lon":495},[499],{"name":500,"role":128,"phone":16,"phoneExt":16,"email":16},"Nikolaos Gorgoraptis",{"type":502,"investigatorFullName":16,"investigatorTitle":16,"investigatorAffiliation":16,"oldNameTitle":16,"oldOrganization":16},"SPONSOR",[504,506,508,510],{"name":505,"class":6},"Lund University",{"name":507,"class":6},"The George Institute for Global Health, Australia",{"name":509,"class":6},"Copenhagen Trial Unit, Center for Clinical Intervention Research",{"name":511,"class":6},"Helsinki University Central Hospital","100532064","stepcare-extended-follow-up-substudy-100532064",false,"NCT06207942","Stepcare Extended Follow-up Substudy","Extended Follow-up Substudy of the Sedation, Temperature and Pressure After Cardiac Arrest and Resuscitation -STEPCARE Trial","All OHCA participants randomized in the STEPCARE trial at the extended follow-up participating sites, who survive and provide consent, with no further inclusion or exclusion criteria.\n\nThe inclusion and exclusion criteria for the STEPCARE trial are:\n\n* Inclusion criteria: out-of-hospital cardiac arrest of non-traumatic origin, minimum of 20 minutes without chest compressions (defined as stable return of spontaneous circulation. ROSC), unconsciousness (defined as not being able to obey verbal commands equal to a FOUR-score motor response of \\\u003C4, or being intubated and sedated because of agitation after sustained ROSC, eligible for intensive care without restrictions or limitation, inclusion within 4 hours (240 minutes) of ROSC (or 220 minutes of stable ROSC).\n* Exclusion criteria: on ECMO prior to randomization, pregnancy, suspected or confirmed intracranial hemorrhage, previously randomized in the STEPCARE trial.\n\nFor caregivers, the eligibility will be that they live with, or have weekly or more frequent contact (in person or over the telephone) with the post OHCA survivor. Only one nominated caregiver per post OHCA survivor will be able to be included in the study. This would typically be the caregiver that would identify as the primary caregiver of the post OHCA survivor if needed, but may also be another close family member.","ALL","18 Years",{"count":522,"type":523},600,"ESTIMATED","INTERVENTIONAL",[526],"NA","To provide detailed information on long-term outcomes in relation to potential neuroprotection and improvements in recovery for different targets of sedation, temperature, and pressure management in post out of hospital cardiac arrest survivors at 6 and 12 months. In addition, the impact of caring for a post OHCA survivor will be explored.",[529,530,531,532],"Cardiac Arrest With Successful Resuscitation","Hypoxia, Brain","Cognitive Impairment","Caregiver Burden","2025-04-17",{"date":535,"type":536},"2025-04-23","ACTUAL",{"date":538,"type":536},"2023-08-01",{"date":540,"type":523},"2027-07-31",{"name":5,"class":6},34]