[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648459":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":18,"responsibleParty":38,"collaborators":42,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":10,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":67,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"University of Campinas, Brazil","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Operated \u003C24h",null,"Patients submited to microsurgical clipping \\\u003C24h after aneurysmal subarachnoid hemorrhage",{"label":13,"type":10,"description":14,"interventionNames":10},"Operated 24-72h","Patients submited to microsurgical clipping between 24h and 72h after aneurysmal subarachnoid hemorrhage",{"label":16,"type":10,"description":17,"interventionNames":10},"Operated >72h","Patients submited to microsurgical clipping \\>72h after aneurysmal subarachnoid hemorrhage",[19],{"facility":20,"status":10,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Clinics Hospital - UNICAMP","Campinas","São Paulo","13083888","Brazil","BR",{"type":27,"coordinates":28},"Point",[29,30],-47.06083,-22.90556,{"lat":30,"lon":29},[33],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Thiago M de Souza, MD","CONTACT","005541999764051","souza.tmagalhaes@gmail.com",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Thiago Magalhaes de Souza","Principal Investigator",[43],{"name":44,"class":45},"Hospital de Clinicas da Unicamp - SP","UNKNOWN","100648459","structural-and-clinical-predictors-of-cognitive-impairment-after-surgical-treatment-for-ruptured-cerebral-aneurysms-100648459",false,"NCT07723131","Structural and Clinical Predictors of Cognitive Impairment After Surgical Treatment for Ruptured Cerebral Aneurysms","Structural and Clinical Predictors of Late Cognitive Impairment After Microsurgical Clipping of Ruptured Cerebral Aneurysms: A Retrospective Cohort With Prospective Assessment","SCOPE-aSAH","Inclusion Criteria:\n\n* Age ≥18 years at the time of aSAH.\n* Treatment by microsurgical clipping of a ruptured cerebral aneurysm.\n* Survival until study recruitment.\n* Ability to understand and sign informed consent.\n\nExclusion Criteria:\n\n* Non-aneurysmal subarachnoid hemorrhage.\n* Exclusively endovascular treatment.\n* Previous diagnosis of dementia.\n* Severe neurological or psychiatric disorders unrelated to aSAH with significant cognitive impact.\n* Absolute contraindication to MRI.\n* Severe aphasia preventing adequate neuropsychological evaluation.\n* Incomplete clinical data.\n* Inability to attend in-person assessment.","ALL",{"count":56,"type":57},150,"ESTIMATED","OBSERVATIONAL","This study investigates the clinical and structural predictors of long-term cognitive impairment in patients who underwent microsurgical clipping for aneurysmal subarachnoid hemorrhage. Using a retrospective cohort with prospective neuropsychological and MRI assessments, it aims to identify factors associated with late cognitive deficits and improve prognostic stratification, rehabilitation planning, and long-term patient care.",[61,62,63],"Subarachnoid Aneurysm Hemorrhage","Microsurgery","Cognitive Impairment",[65,66,63],"Aneurysmal Subarachnoid Hemorrhage","Aneurysm Clipping","NOT_YET_RECRUITING","2026-07-20",{"date":70,"type":71},"2026-07-23","ACTUAL",{"date":73,"type":57},"2026-08",{"date":75,"type":57},"2029-12",{"name":5,"class":6},1]