[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100647000":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":56,"collaborators":23,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":23,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":23,"enrollmentInfo":67,"targetDuration":23,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":23,"overallStatus":77,"whyStopped":23,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Western Sydney Local Health District","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Snare Tip Soft Coagulation (STSC)","ACTIVE_COMPARATOR","Circumferential thermal ablation of the resection margin will be performed using the distal tip of a standard polypectomy snare in soft coagulation mode. The tip will be applied sequentially to the entire visible mucosal defect margin to achieve complete circumferential treatment.",[13],"Procedure: Snare Tip Soft Coagulation (STSC)",{"label":15,"type":10,"description":16,"interventionNames":17},"Hybrid APC (ERBE)","Circumferential thermal ablation of the resection margin will be performed using Hybrid APC (ERBE) in standard APC mode. The argon plasma beam will be applied sequentially to the entire visible mucosal defect margin to achieve complete circumferential treatment. Electrosurgical settings will be standardized according to unit protocol (effect and wattage predefined for Hybrid APC use).",[18],"Procedure: Hybrid APC (ERBE)",[20,24],{"type":21,"name":9,"description":11,"armGroupLabels":22,"otherNames":23},"PROCEDURE",[9],null,{"type":21,"name":15,"description":16,"armGroupLabels":25,"otherNames":23},[15],[27],{"name":28,"affiliation":29,"role":30},"Michael J Bourke, MBBS","WSLHD","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":23,"email":36},"Kathleen Goodrick, BN","CONTACT","+612 88905555","kathleen.goodrick@health.nsw.gov.au",{"name":38,"role":34,"phone":35,"phoneExt":23,"email":39},"Mayan Eitan, MD","mayan.eitan@health.nsw.gov.au",[41],{"facility":42,"status":23,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Westmead Hospital","Sydney","New South Wales","2145","Australia","AU",{"type":49,"coordinates":50},"Point",[51,52],151.20732,-33.86785,{"lat":52,"lon":51},[55],{"name":33,"role":34,"phone":35,"phoneExt":23,"email":36},{"type":30,"investigatorFullName":57,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Professor Michael Bourke","100647000","stsc-hybridapc-trial-100647000",false,"NCT07682805","STSC-HybridAPC Trial","Snare Tip Soft Coagulation Versus Hybrid APC (ERBE) for Post-EMR Margin Thermal Ablation - A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥18 years\n* Undergoing piecemeal EMR of a non-pedunculated colorectal lesion ≥20 mm in size\n* Macroscopically complete resection achieved prior to margin ablation (no visible residual adenomatous tissue at the resection base)\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Lesions requiring en bloc resection by ESD\n* Lesions with suspected deep submucosal invasion based on endoscopic assessment (e.g., depressed morphology, non-lifting sign, NICE type 3 pattern, or equivalent advanced imaging criteria)\n* Inflammatory bowel disease with active colitis at the lesion site\n* Overt invasive carcinoma requiring surgical management\n* Pregnancy\n* Inability to provide informed consent","ALL","18 Years",{"count":68,"type":69},140,"ESTIMATED","INTERVENTIONAL",[72],"NA","Margin thermal ablation after piecemeal EMR significantly reduces recurrence of large colorectal polyps. As recurrence rates are now low, the key implementation question relates to efficiency and reproducibility of different ablation techniques. This randomized controlled trial compares snare tip soft coagulation (STSC) with Hybrid APC (ERBE), with procedural time as the primary endpoint.",[75,76],"Colon Adenomas","Colon Adenomatous Polyp","NOT_YET_RECRUITING","2026-06-26",{"date":80,"type":81},"2026-07-06","ACTUAL",{"date":83,"type":69},"2027-01-01",{"date":85,"type":69},"2027-08-15",{"name":5,"class":6},1]