[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100659698":3},{"organization":4,"outcomesModule":7,"designInfo":21,"detailedDescription":27,"studyPopulation":16,"armGroups":28,"interventions":35,"overallOfficials":16,"centralContacts":41,"locations":47,"responsibleParty":67,"collaborators":16,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":16,"enrollmentInfo":82,"targetDuration":16,"studyType":85,"phases":86,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":49,"whyStopped":16,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Groupe Hospitalier Diaconesses Croix Saint-Simon","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":16},[9],{"measure":10,"description":11,"timeFrame":12},"Quantitative and Qualitative Parameters of General Fetal Movements Assessed by Ultrasound Recordings Across Gestation","Presence, frequency, and characteristics of abnormal fetal movement patterns identified on ultrasound recordings obtained at 13, 17, 23, and 33 weeks of amenorrhea (±10 days). Recordings will be independently assessed by experts in fetal ultrasonography and General Movements Assessment using the General Movements Assessment grid adapted for preterm infants. Reported outcomes will include the occurrence and type of abnormal movement patterns at each assessment time point.","9 months",[14,18],{"measure":15,"description":16,"timeFrame":17},"General Movement Patterns at 0 to 4 Weeks and 11 to 16 Weeks After Birth Assessed From Video Recordings",null,"Week 4 and week 16",{"measure":19,"description":16,"timeFrame":20},"Child Development Scores Assessed by Pediatric Developmental Questionnaires at 12 and 24 Months of Age","Year 1 and year 2",{"allocation":22,"interventionModel":23,"interventionModelDescription":16,"primaryPurpose":24,"observationalModel":16,"timePerspective":16,"maskingInfo":25},"NA","SINGLE_GROUP","DIAGNOSTIC",{"masking":26,"maskingDescription":16,"whoMasked":16},"NONE","The identification of General Movements (GMs) in utero is not common practice among ultrasound technicians. However, it has been shown that poor or abnormal general movements in premature or full-term infants is a marker of the risk of later developing autism spectrum disorders or neurodevelopmental disorders. Prenatal screening currently focuses on detecting morphological malformations rather than the quality of general movements. Movement stimulates brain development through epigenetic action, and ultrasound enables this development to be monitored during pregnancy. General movements have been little studied in the foetus, and the introduction of a reading grid enabling general movements to be identified in utero could provide a new tool for ultrasound scanners in identifying risk situations at perinatal and\u002For postnatal level.\n\nThe investigators hypothesise that analysing ultrasound recordings as part of this research could lead to the creation of a grid to help identify general movements in utero. This would be a first step towards introducing a new tool for ultrasound technicians to use in the early detection of autism spectrum disorders or neurodevelopmental deficits.",[29],{"label":30,"type":31,"description":32,"interventionNames":33},"Pregnant women treated in the gynaecology-obstetrics department","EXPERIMENTAL","In addition to the standard follow-up ultrasound, pregnant participants treated in the gynaecology-obstetrics department, will be offered a research-specific endovaginal or external ultrasound at 13, 17 (if an amniocentesis is performed), 23 and 33 weeks of amenorrhoea (±10 days). On average, 10% of ultrasounds are endovaginal and 90% are external.",[34],"Procedure: External or endovaginal ultrasound",[36],{"type":37,"name":38,"description":39,"armGroupLabels":40,"otherNames":16},"PROCEDURE","External or endovaginal ultrasound","Endovaginal or external ultrasound specifically for research at 13, 17 (if amniocentesis), 23 and 33 weeks of amenorrhoea (+\u002F- 10 days) (on average 10% endovaginal \u002F 90% external ultrasound). Each patient will undergo one to four additional ultrasound scans.",[30],[42],{"name":43,"role":44,"phone":45,"phoneExt":16,"email":46},"Djazia Bouzelmat, Clinical Research Assistant","CONTACT","01 44 64 30 98","dbouzelmat@hopital-dcss.org",[48],{"facility":5,"status":49,"city":50,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Paris","75012","France","FR",{"type":55,"coordinates":56},"Point",[57,58],2.3488,48.85341,{"lat":58,"lon":57},[61,64],{"name":62,"role":44,"phone":63,"phoneExt":16,"email":46},"Djazia BOUZELMAT, Clinical Research Assistant","0144643098",{"name":65,"role":66,"phone":16,"phoneExt":16,"email":16},"François FARGES, Doctor","PRINCIPAL_INVESTIGATOR",{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":16,"oldOrganization":16},"SPONSOR_INVESTIGATOR","François FARGES","gynaecologist","100659698","study-of-general-foetal-movements-using-ultrasound-100659698",false,"NCT07868185","Study of General Foetal Movements Using Ultrasound","Ultrasound Study of the Foetus's General Movements","FETAL-GMs","Inclusion Criteria:\n\n* Patient aged over 18\n* Pregnant from 13 weeks of amenorrhoea\n* Indication for an ultrasound scan as part of the usual monitoring of her pregnancy\n* With no particular history or who has had a child with autism spectrum disorders or neurodevelopmental disorders\n* Able to understand the benefits and constraints of the research\n* Having given signed consent to participate, as well as that of his\u002Fher spouse.\n* Beneficiary of a social security scheme or entitled person (excluding AME).\n\nExclusion Criteria:\n\n* Pathological pregnancy\n* Under guardianship, curatorship or legal protection.",true,"FEMALE","18 Years",{"count":83,"type":84},75,"ESTIMATED","INTERVENTIONAL",[22],"This research explores General Movements (GMs) in a reference population. Abnormal general movements in babies are predictive of autism spectrum disorders or neurodevelopmental deficits.\n\nGeneral movements have received little attention in the context of foetuses, which is why developing a reading grid to analyse general movements in foetuses could be a valuable tool for facilitating early diagnosis and prompt treatment of at-risk babies.",[89,90],"Pregnant Woman","Foetus Abnormal General Movements",[92,93,94,95],"Ultrasound recordings","General Movements Grid","Autism spectrum disorders in the foetus","Neurodevelopmental deficits in the foetus","2026-10-05",{"date":98,"type":99},"2026-10-09","ACTUAL",{"date":101,"type":99},"2023-02-14",{"date":103,"type":84},"2029-02-14",{"name":69,"class":6},1]