[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100654313":3},{"organization":4,"outcomesModule":7,"designInfo":21,"detailedDescription":20,"studyPopulation":24,"armGroups":25,"interventions":30,"overallOfficials":20,"centralContacts":35,"locations":42,"responsibleParty":61,"collaborators":20,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":77,"studyType":78,"phases":20,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":86,"whyStopped":20,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University Hospital, Toulouse","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":20},[9],{"measure":10,"description":11,"timeFrame":12},"Construction of a database of electrophysiological signatures of various cognitive functions","Correlation of performance on a task involving a neurocognitive process with characteristics of brain activity recorded during the task (electrophysiological signature) using intracranial stereo-electroencephalography (SEEG) electrodes.","3 weeks after the inclusion",[14,17],{"measure":15,"description":16,"timeFrame":12},"Evaluation of the impact of epilepsy on these electrophysiological signatures","Significant impact of the patient's epilepsy on the normal electrophysiological signature expected during certain cognitive processes.",{"measure":18,"description":19,"timeFrame":12},"Determine whether a given brain region is dysfunctional in certain epileptic patients by comparing it with the atlas of normal physiological signatures.","Identification of a dysfunctional brain region in an epileptic patient if the electrophysiological signature differs significantly from that expected based on the atlas.",null,{"allocation":20,"interventionModel":20,"interventionModelDescription":20,"primaryPurpose":20,"observationalModel":22,"timePerspective":23,"maskingInfo":20},"COHORT","PROSPECTIVE","patients with drug-resistant epilepsy hospitalized for stereo-electroencephalography",[26],{"label":27,"type":20,"description":20,"interventionNames":28},"Patients hospitalized for SEEG with cognitive tasks",[29],"Other: Cognitive tasks in the form of questionnaires",[31],{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":20},"Cognitive tasks in the form of questionnaires","During their hospitalization for SEEG, patients will perform cognitive tasks to assess memory, vision, attention, language, and decision-making.",[27],[36],{"name":37,"role":38,"phone":39,"phoneExt":40,"email":41},"Jonathan Curot, PHD","CONTACT","05 61 77 94 88","+33","curot.j@chu-toulouse.fr",[43],{"facility":44,"status":20,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Electrophysiologie cérébrale, épilepsie, sommeil, Hôpital Pierre Paul Riquet","Toulouse","Oui","31000","France","FR",{"type":51,"coordinates":52},"Point",[53,54],1.44367,43.60426,{"lat":54,"lon":53},[57],{"name":58,"role":38,"phone":59,"phoneExt":40,"email":60},"Emeline Muller","0561778707","muller.E@chu-toulouse.Fr",{"type":62,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100654313","study-of-the-intracerebral-electrophysiological-signature-in-the-epileptic-patient-100654313",false,"NCT07796984","Study of the Intracerebral Electrophysiological Signature in the Epileptic Patient","Study of the Intracerebral Electrophysiological Signature of Cognitive Processes and Functional Mapping in Patients With Drug-resistant Epilepsy","ACTELIN 2","Inclusion Criteria:\n\n* Patient with drug-resistant focal epilepsy undergoing SEEG evaluation as part of the pre-surgical workup for epilepsy\n* Intellectual capacity sufficient to perform cognitive tasks, receive information about the study procedure, and understand the information sheet\n\nExclusion Criteria:\n\n* Patients already participating in another research project that prohibits participation in another study","ALL","18 Years","65 Years",{"count":75,"type":76},75,"ESTIMATED","3 Weeks","OBSERVATIONAL","As part of the clinical management of certain severe, drug-resistant forms of epilepsy, it is necessary to implant electrodes in the brain to identify the epileptic network prior to potential neurosurgical resection of the source zones. This standardized procedure, known as Stereo-Electroencephalography (SEEG), was developed in France in the 1960s. The electrodes remain implanted for several days-typically two weeks-while awaiting spontaneous epileptic seizures. During this period, the patient remains hospitalized, and their electroencephalographic activity is recorded around the clock.\n\nPatients can be asked to perform cognitive tasks (such as tasks involving memory, attention, vision, language, and decision-making) while awake or asleep; the results can then be correlated with the intracerebral electroencephalographic activity recorded simultaneously as part of their clinical care. This approach makes it possible to capture the electrophysiological signatures of specific cognitive processes, thereby enabling researchers to: 1) create a brain map of electrophysiological signatures, 2) improve standard models of cognitive function, and 3) study the dysfunction of these processes in epilepsy.",[81],"Epilepsy",[83,84,85],"epilepsy","cognitive task","stereoelectroencephalography","NOT_YET_RECRUITING","2026-08-27",{"date":89,"type":90},"2026-09-01","ACTUAL",{"date":92,"type":76},"2026-10-01",{"date":94,"type":76},"2031-10-31",{"name":5,"class":6},1]