[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100650278":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":18,"responsibleParty":32,"collaborators":7,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":7,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":44,"maxAge":7,"enrollmentInfo":45,"targetDuration":7,"studyType":48,"phases":7,"briefSummary":49,"conditions":50,"keywords":52,"overallStatus":56,"whyStopped":7,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},{"fullName":5,"class":6},"Beijing Municipal Administration of Hospitals","OTHER_GOV",null,[9,14],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Minghui Li, Dr","CONTACT","+8613693259096","wuhm2000@sina.com",{"name":15,"role":11,"phone":16,"phoneExt":7,"email":17},"Weihua Cao, Dr","+8618811333139","weihuacaohappy@163.com",[19],{"facility":20,"status":7,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":7},"Beijing Ditan Hospital, Capital Medical University","Beijing","Beijing Municipality","100015","China","CN",{"type":27,"coordinates":28},"Point",[29,30],116.39723,39.9075,{"lat":30,"lon":29},{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Minghui Li","Head of Department","100650278","study-on-clinicopathological-features-influencing-factors-and-clinical-outcomes-in-patients-with-psvd-100650278",false,"NCT07744048","Study on Clinicopathological Features, Influencing Factors and Clinical Outcomes in Patients With PSVD","Study on Clinicopathological Features, Influencing Factors and Clinical Outcomes in Patients With Porto-sinusoidal Vascular Disease (PSVD)","Inclusion Criteria:\n\n1. Patients histopathologically diagnosed with porto-sinusoidal vascular disorder (PSVD) via liver needle biopsy;\n2. Liver biopsy specimen length ≥ 10 mm (or assessed as diagnostically adequate by a pathologist), with no histological evidence of cirrhosis;\n3. Meeting the established diagnostic criteria for PSVD.\n\nExclusion Criteria:\n\n1. Concomitant Budd-Chiari syndrome or other hepatic venous outflow obstruction diseases;\n2. Concomitant congenital hepatic fibrosis, hepatic sarcoidosis, or sinusoidal obstruction syndrome;\n3. Concomitant hepatocellular carcinoma or other hepatic malignancies;\n4. Age \\\u003C 18 years;\n5. Severe deficiency of clinical data that precludes valid analysis.","ALL","18 Years",{"count":46,"type":47},150,"ESTIMATED","OBSERVATIONAL","This retrospective-prospective cohort study investigates portal sinusoidal vascular disorder (PSVD), a liver vascular disease definitively diagnosed via liver biopsy. Addressing PSVD's poorly defined natural history, unclear prognostic determinants and the scarcity of large-scale systematic research in China, the study enrolls histopathologically confirmed patients, collects baseline clinicopathological, laboratory and imaging data, tracks endpoints including transplant-free survival, liver-related events and portal vein thrombosis changes, and conducts prognostic analyses using Cox regression, Kaplan-Meier method and Fine-Gray model, aiming to characterize disease features, identify key prognostic factors, verify high-risk subgroups with inferior outcomes, and support precise clinical management while filling relevant domestic research gaps.",[51],"Porto-Sinusoidal Vascular Diseases",[53,54,55],"Porto-sinusoidal vascular disorder","PSVD","INCPH","NOT_YET_RECRUITING","2026-08-01",{"date":59,"type":60},"2026-08-04","ACTUAL",{"date":57,"type":47},{"date":63,"type":47},"2028-07-30",{"name":5,"class":6},1]