[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100652825":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":31,"responsibleParty":46,"collaborators":31,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":31,"eligibilityCriteria":55,"healthyVolunteers":52,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":31,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":70,"whyStopped":31,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":31},{"fullName":5,"class":6},"People's Hospital of Anshun City of Guizhou Province","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Submental endoscopic-assisted Sistrunk operation","EXPERIMENTAL","After general anesthesia, the patient lies in a supine position with the neck slightly extended backward. A concealed incision of approximately 2-3 centimeters in length is made along the natural skin fold at about 1 centimeter below the chin (the submental area). Through this incision, a blunt dissection is performed at the subcutaneous thin muscle layer level to form a subcutaneous tunnel that extends directly to the thyroid cartilage region. The surgery is assisted by an endoscope with a suspension and traction system and without the need for inflation. Under high-definition endoscopic visualization, the thyroglossal duct cyst, the middle segment of the hyoid bone, and the path of the thyroglossal duct are carefully separated and completely resected. A closed drainage tube is placed. The submental incision is sutured using absorbable sutures within the dermis.",[13],"Other: In the control group",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional open Sistrunk operation via cervical incision","ACTIVE_COMPARATOR","After general anesthesia, the patient is placed in the supine position with the neck extended. A horizontal skin incision is made along the midline of the neck directly over the thyroglossal duct cyst. The skin and subcutaneous tissues are divided. The strap muscles (sternohyoid and thyrohyoid) are separated in the midline to expose the cyst and the body of the hyoid bone. The thyroglossal duct cyst is dissected en bloc together with the central portion of the hyoid bone, preserving the surrounding vital structures. The surgical wound is thoroughly irrigated with normal saline. The incision is closed in layers with absorbable sutures, and a sterile dressing is applied.",[19],"Procedure: The experimental group",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","The experimental group","After general anesthesia, the patient is placed in the supine position with the neck slightly extended. A concealed transverse skin incision of approximately 2-3 cm is made about 1 cm below the chin (submental area), following the natural skin creases. Through this incision, blunt dissection is performed in the subplatysmal plane to create a subcutaneous tunnel reaching the hyoid bone region. The operation is assisted by an endoscope with a suspended retractor system without gas insufflation, thus avoiding the risk of gas embolism. Under high-definition endoscopic visualization, the thyroglossal duct cyst, the middle segment of the hyoid bone, and the track of the thyroglossal duct are meticulously dissected and completely resected en bloc. Hemostasis is achieved carefully to preserve the recurrent laryngeal and hypoglossal nerves. The wound is thoroughly irrigated with normal saline. A closed suction drain is placed if necessary. The submental incision is closed with intradermal absor",[15],[9],{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"In the control group","Make an incision in the middle of the skin on the neck, cut through the skin and subcutaneous tissue, expose the tumor and the hyoid bone, and completely remove the thyroglossal",[9],null,[33],{"name":34,"affiliation":5,"role":35},"fei L Yue, PG","STUDY_DIRECTOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":31,"email":41},"Guang J Tang, MD","CONTACT","86+ 13595302195","tgjdoctor@163.com",{"name":43,"role":39,"phone":44,"phoneExt":31,"email":45},"Xing Y Lan, MB","86+ 13595361911","lyxassymyy2022@163.com",{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Guangjun Tang","associate chief physician","100652825","study-on-the-efficacy-of-laparoscopic-assisted-thyroglossal-duct-cyst-resection-via-submental-approach-100652825",false,"NCT07778485","Study on the Efficacy of Laparoscopic-Assisted Thyroglossal Duct Cyst Resection Via Submental Approach","Inclusion Criteria:\n\n* The cyst is in the non-acute infection stage;\n\n  * The cyst has not ruptured to form a skin sinus tract or fistula;\n\n    * Preoperative B-ultrasound and CT indicated that it was a thyroglossal duct cyst;\n\n      * There are no severe underlying heart or lung diseases or coagulation dysfunction;\n\n        * The patient and their family voluntarily chose to undergo laparoscopic resection of the thyroglossal duct cyst; ⑥ The patient and their family voluntarily signed the informed consent form.\n\nExclusion Criteria:\n\n* The cyst is in the acute infection stage;\n\n  * The cyst ruptures, forming a skin sinus tract or fistula; ③ Has severe underlying heart and lung diseases and coagulation dysfunction; ④ Those with cyst diameters greater than 4 cm; ⑤ Those currently participating in other research studies.","ALL","3 Years","65 Years",{"count":60,"type":61},60,"ESTIMATED","INTERVENTIONAL",[64],"NA","Thyroglossal duct cysts are congenital diseases of the neck. Once detected, surgical treatment is the first choice. The traditional Sistrunk surgery has definite efficacy but leaves scars on the neck. With the popularization of the concept of minimally invasive surgery, the non-inflated submandibular approach endoscopic technique provides a new idea for achieving a scar-free resection of the neck. This project intends to conduct a randomized controlled study to scientifically evaluate the clinical efficacy and safety of submandibular approach endoscopic-assisted resection of thyroglossal duct cysts.\n\nThe study plans to include 60 newly diagnosed patients, randomly divided into the experimental group (submandibular approach endoscopic resection of thyroglossal duct cysts) and the control group (traditional open surgery). Systematically compare the perioperative indicators (operation time, intraoperative blood loss, average hospital stay), postoperative pain (VAS score), complications (infection, recurrence, injury of the sublingual nerve), and incision satisfaction (Vancouver Scar Scale) between the two groups.\n\nThis project is expected to establish a standardized surgical procedure, verify the superiority of this technique in achieving a scar-free neck while ensuring complete resection of the lesion, provide evidence-based medical evidence for the promotion of scar-free surgery in the neck, and have both clinical innovation and social benefits.",[67],"Thyroglossal Cyst",[69],"Thyroglossal Cyst Submental approach Efficacy study","NOT_YET_RECRUITING","2026-08-19",{"date":73,"type":74},"2026-08-21","ACTUAL",{"date":76,"type":61},"2026-09-01",{"date":78,"type":61},"2028-06-30",{"name":5,"class":6}]