[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100655814":3},{"organization":4,"outcomesModule":7,"designInfo":18,"detailedDescription":26,"studyPopulation":17,"armGroups":27,"interventions":44,"overallOfficials":50,"centralContacts":54,"locations":60,"responsibleParty":75,"collaborators":78,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":84,"sex":90,"minAge":91,"maxAge":17,"enrollmentInfo":92,"targetDuration":17,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":103,"overallStatus":63,"whyStopped":17,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Ohio State University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":17},[9],{"measure":10,"description":11,"timeFrame":12},"Suicide attempts during follow-up","The primary outcome is suicide attempts during follow-up, assessed with the Self-Injurious Thoughts and Behaviors Interview-Revised (SITBI-R). SITBI-R responses will be used to determine the rate of participants making a follow-up suicide attempt (binary) and the rate of follow-up suicide attempts per participant-year across treatment arms.","From enrollment to the end of study completion at one year.",[14],{"measure":15,"description":16,"timeFrame":12},"Suicidal Cognitions and Suicidal Ideation","Suicidal beliefs will be assessed using the SCS-R.15 SCS-R scores assess future risk for attempting suicide. Severity of suicidal ideation will be assessed using the Scale for Suicide Ideation (SSI),16 a 19-item self-report scale that measures the intensity of suicide-related thoughts, urges, and behaviors.",null,{"allocation":19,"interventionModel":20,"interventionModelDescription":17,"primaryPurpose":21,"observationalModel":17,"timePerspective":17,"maskingInfo":22},"RANDOMIZED","SEQUENTIAL","PREVENTION",{"masking":23,"maskingDescription":17,"whoMasked":24},"SINGLE",[25],"OUTCOMES_ASSESSOR","Funded by The Jordan Elizabeth Harris Foundation, this study uses a Sequential Multiple Assignment Randomized Trial (SMART) design to evaluate how various sequences and doses of BCBT components differentially impact suicide risk. In this two-stage clinical trial, all participants will initially receive 4 sessions of BCBT and complete weekly assessments. They will also complete 4 weeks of ecological momentary assessment (EMA) and digital phenotyping procedures during the first month of treatment.",[28,33,37,41],{"label":29,"type":6,"description":30,"interventionNames":31},"Reasons for Living","Participants will complete reasons for living in session 2, physiological regulation in session 3, and sleep in session 4.",[32],"Behavioral: Brief Cognitive Behavioral Therapy",{"label":34,"type":6,"description":35,"interventionNames":36},"Sleep","Sleep in session 2, physiological regulation in session 3, and reasons for living in session 4.",[32],{"label":38,"type":6,"description":39,"interventionNames":40},"Cognitive Reappraisal","Beginning at week 4, participants will be classified as treatment responders if they (1) have not engaged in any preparatory behavior or made any suicide attempts (aborted, interrupted, or actual) and (2) have an SCS-R total score ≤21. Participants who do not meet these criteria will continue BCBT and be randomized a second time to determine if cognitive reappraisal or behavioral activation components are delivered next (sessions 5-9).",[32],{"label":42,"type":6,"description":39,"interventionNames":43},"Behavioral Activation",[32],[45],{"type":46,"name":47,"description":48,"armGroupLabels":49,"otherNames":17},"BEHAVIORAL","Brief Cognitive Behavioral Therapy","In this study, BCBT skills will be introduced in various randomly determined sequence. During the first stage, around half of participants will complete reasons for living in session 2, physiological regulation in session 3, and sleep in session 4. The other half of participants will complete these components in the reverse order: sleep in session 2, physiological regulation in session 3, and reasons for living in session 4. Treatment non-responders will continue attending BCBT sessions during Stage 2 following their 4 completed sessions in Stage 1, up to a maximum of 6 additional sessions (i.e., 10 therapy sessions total across both stages). The specific sequence of the BCBT skills used in Stage 2 will be randomly assigned.",[42,38,29,34],[51],{"name":52,"affiliation":5,"role":53},"Melanie Bozzay, PhD","PRINCIPAL_INVESTIGATOR",[55],{"name":56,"role":57,"phone":58,"phoneExt":17,"email":59},"Anna Crouser, MSW, LSW","CONTACT","614-293-2554","anna.crouser@osumc.edu",[61],{"facility":62,"status":63,"city":64,"state":65,"zip":66,"country":67,"countryCode":68,"cosmosGeoPoint":69,"geoPoint":74,"contacts":17},"Department of Psychiatry and Behavioral Health","RECRUITING","Columbus","Ohio","43210","United States","US",{"type":70,"coordinates":71},"Point",[72,73],-82.99879,39.96118,{"lat":73,"lon":72},{"type":53,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":17,"oldOrganization":17},"Melanie Bozzay","Director of Suicide Prevention, Associate Professor",[79],{"name":80,"class":81},"The Jordan Elizabeth Harris Foundation","UNKNOWN","100655814","study-to-refine-the-effectiveness-of-new-generation-therapies-for-suicide-100655814",false,"NCT07818889","Study to Refine the Effectiveness of New Generation Therapies for Suicide","STRENGTHENS: Study To Refine the Effectiveness of New Generation Therapies for Suicide","STRENGTHENS","Inclusion Criteria:\n\n* 18 years of age or older; suicidal ideation (assessed with the SSI) and\u002For suicidal behavior within the past month (assessed with the SITBI-R), psychiatric hospitalization for elevated suicide risk within the past month, and\u002For SCS-R total score \\>21; eligibility to understand and speak the English language; ability to complete the informed consent process\n\nExclusion Criteria:\n\n* impaired mental status that precludes the ability to provide informed consent (e.g., intoxication, psychosis, mania) and\u002For a medical or psychiatric condition that precludes the ability to engage in outpatient therapy","ALL","18 Years",{"count":93,"type":94},50,"ESTIMATED","INTERVENTIONAL",[97],"NA","The purpose of this research study is to improve the effectiveness of a well-established therapy for suicidal thoughts and behaviors called Brief Cognitive Behavioral Therapy (BCBT) for Suicide Prevention.",[100,101,102],"Suicide Risk","Suicide Attempt","Treatment Response",[104,105,106],"suicide risk","suicide attempt","suicidality","2026-09-08",{"date":109,"type":110},"2026-09-14","ACTUAL",{"date":112,"type":110},"2026-04-29",{"date":114,"type":94},"2029-12-31",{"name":5,"class":6},1]