[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648697":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":44,"centralContacts":45,"locations":55,"responsibleParty":71,"collaborators":44,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":44,"eligibilityCriteria":82,"healthyVolunteers":78,"sex":83,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":44,"studyType":89,"phases":90,"briefSummary":92,"conditions":93,"keywords":97,"overallStatus":106,"whyStopped":44,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"Istanbul University - Cerrahpasa","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1: Neurodevelopmental Treatment (NDT)","ACTIVE_COMPARATOR","Participants will receive neurodevelopmental treatment alone, delivered in 45-minute sessions, 3 days per week for 8 weeks (24 sessions in total).",[13],"Other: Neurodevelopmental Treatment",{"label":15,"type":16,"description":17,"interventionNames":18},"Group 2: NDT + High-Repetition Task-Oriented Training","EXPERIMENTAL","Participants will receive 45 minutes of neurodevelopmental treatment followed by 30 minutes of high-repetition task-oriented training targeting the lower extremity in each session (approximately 75 minutes in total), 3 days per week for 8 weeks (24 sessions in total).",[19],"Other: High-Repetition Task-Oriented Training",{"label":21,"type":16,"description":22,"interventionNames":23},"Group 3: NDT + High-Intensity Gait Training","Participants will receive 45 minutes of neurodevelopmental treatment followed by 30 minutes of high-intensity gait training in each session (approximately 75 minutes in total), 3 days per week for 8 weeks (24 sessions in total).",[24],"Other: High-Intensity Gait Training",[26,32,38],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"Neurodevelopmental Treatment","Conventional neurodevelopmental treatment delivered in 45-minute sessions, 3 days per week for 8 weeks, focusing on postural control, weight transfer, selective movement of the lower extremity, and facilitation of normal movement patterns. All sessions will be delivered by a single experienced physiotherapist.",[9],[31],"NDT",{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"High-Repetition Task-Oriented Training","Structured, task-specific lower extremity training performed at high repetition volumes for 30 minutes per session, in addition to neurodevelopmental treatment. Training includes functional tasks such as sit-to-stand, stepping, and weight-shifting activities, with the number of repetitions and task difficulty progressed individually based on participant performance.",[15],[37],"HRTOT",{"type":6,"name":39,"description":40,"armGroupLabels":41,"otherNames":42},"High-Intensity Gait Training","Walking-based training performed for 30 minutes per session at high aerobic intensity, in addition to neurodevelopmental treatment. Training intensity will be progressively adjusted and monitored using target heart rate and ratings of perceived exertion.",[21],[43],"HIGT",null,[46,51],{"name":47,"role":48,"phone":49,"phoneExt":44,"email":50},"Emrah Zirek, Ph. D.","CONTACT","+904262160012","zireke@gmail.com",{"name":52,"role":48,"phone":53,"phoneExt":44,"email":54},"Samet Tatli, MD","+905XXXXXXXXX","drsamettatli@gmail.com",[56],{"facility":57,"status":44,"city":58,"state":59,"zip":60,"country":61,"countryCode":44,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"Bingol State Hospital - City: Bingöl, Country: Türkiye (listede \"Turkey\" olarak geçebilir), Zip: 12000","Bingoel","Center","12000","Turkey (Türkiye)",{"type":63,"coordinates":64},"Point",[65,66],40.49389,38.88472,{"lat":66,"lon":65},[69],{"name":52,"role":48,"phone":70,"phoneExt":44,"email":54},"+90 XXX XXX XX XX",{"type":72,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":75,"oldNameTitle":44,"oldOrganization":44},"PRINCIPAL_INVESTIGATOR","Emrah Zirek","Assistant Professor","Bingol University","100648697","task-oriented-training-versus-high-intensity-gait-training-in-people-with-chronic-stroke-100648697",false,"NCT07725211","Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke","High-Repetition Task-Oriented Training Versus High-Intensity Gait Training for Lower Extremity Rehabilitation in Individuals With Chronic Stroke: An Assessor-Blinded Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of first-ever unilateral stroke (ischemic or hemorrhagic) confirmed by clinical and\u002For radiological findings\n* Time since stroke onset of at least 6 months (chronic phase)\n* Age between 18 and 75 years\n* Ability to walk at least 10 meters independently, with or without an assistive device\n* Functional Ambulation Category (FAC) score of 3 or higher\n* Sufficient cognitive ability to understand and follow instructions (Mini-Mental State Examination score ≥ 24)\n* Willingness to participate and provision of written informed consent\n\nExclusion Criteria:\n\n* Recurrent stroke or bilateral hemispheric involvement\n* Unstable cardiovascular disease or other medical conditions contraindicating high-intensity exercise\n* Severe lower extremity spasticity interfering with gait training (Modified Ashworth Scale score \\> 3)\n* Orthopedic, rheumatological, or other neurological conditions affecting gait\n* Severe visual or vestibular impairment\n* Severe aphasia or cognitive impairment preventing participation in training or assessments\n* Participation in another structured rehabilitation or exercise program during the study period\n* Botulinum toxin injection to the lower extremity within the last 6 months","ALL","18 Years","75 Years",{"count":87,"type":88},45,"ESTIMATED","INTERVENTIONAL",[91],"NA","The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke.\n\nForty-five participants will be randomly assigned to one of three groups: (1) neurodevelopmental treatment (NDT) alone, (2) NDT combined with high-repetition task-oriented training, or (3) NDT combined with high-intensity gait training. All participants will receive treatment 3 days per week for 8 weeks (24 sessions in total). Walking capacity (6-Minute Walk Test) and functional mobility (Timed Up and Go Test, modified Dynamic Gait Index, 10-Meter Walk Test) will be assessed before and after the intervention by an assessor blinded to group allocation. The study hypothesizes that adding structured, intensity-based training approaches to conventional NDT will lead to greater improvements in walking capacity than NDT alone.",[94,95,96],"Stroke","Hemiplegia","Chronic Stroke",[98,99,100,101,102,103,104,105],"Task-oriented training","High-intensity gait training","Neurodevelopmental treatment","Walking capacity","Gait rehabilitation","Functional mobility","6-Minute Walk Test","Randomized controlled trial","NOT_YET_RECRUITING","2026-07-21",{"date":109,"type":110},"2026-07-24","ACTUAL",{"date":112,"type":88},"2026-08-15",{"date":114,"type":88},"2026-12-15",{"name":5,"class":6},1]