[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100646695":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":58,"collaborators":61,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":24,"eligibilityCriteria":71,"healthyVolunteers":72,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":24,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":24,"overallStatus":85,"whyStopped":24,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Ohio State University Comprehensive Cancer Center","OTHER",[8,14],{"label":9,"type":6,"description":10,"interventionNames":11},"Arm I (IQOS HeatSticks, Usual Brand Cigarette [UBC])","Participants use IQOS HeatSticks (flavor matched to their usual cigarette) ad lib over 60 minutes during laboratory visit 1. At least forty-eight hours later, participants smoke their UBC ad lib over 60 minutes during laboratory visit 2.",[12,13],"Behavioral: Smoking Behavioral Research (IQOS)","Behavioral: Smoking Behavioral Research (UBC)",{"label":15,"type":6,"description":16,"interventionNames":17},"Arm II (UBC, IQOS HeatSticks)","Participants smoke their UBC ad lib over 60 minutes during laboratory visit 1. At least forty-eight hours later, participants use IQOS HeatSticks (flavor matched to their usual cigarette) ad lib over 60 minutes during laboratory visit 2.",[12,13],[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","Smoking Behavioral Research (IQOS)","Use IQOS HeatSticks (flavor matched to the participant's usual cigarette)",[9,15],null,{"type":20,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Smoking Behavioral Research (UBC)","Smoke UBC",[9,15],[30],{"name":31,"affiliation":5,"role":32},"Alayna P Tackett, PhD","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"The Ohio State University Comprehensive Cancer Center","CONTACT","800-293-5066","OSUCCCClinicaltrials@osumc.edu",[40],{"facility":5,"status":24,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Columbus","Ohio","43210","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-82.99879,39.96118,{"lat":50,"lon":49},[53,57],{"name":54,"role":36,"phone":55,"phoneExt":24,"email":56},"Alayna P. Tackett, PhD","844-744-2447","Tackett-Lab@osumc.edu",{"name":54,"role":32,"phone":24,"phoneExt":24,"email":24},{"type":32,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Alayna Tackett","Principal Investigator",[62],{"name":63,"class":64},"National Cancer Institute (NCI)","NIH","100646695","the-abuse-liability-of-iqos-heated-tobacco-products-among-adults-who-smoke-100646695",false,"NCT07688304","The Abuse Liability of IQOS Heated Tobacco Products Among Adults Who Smoke","Studying User Sensory Experiences and Smoking Behavior of IQOS Heated Tobacco Products to Improve Harm Reduction Among Adult Cigarette Smokers","Inclusion Criteria:\n\n* Adults 21-65 years\n* Adults who smoke (defined as ≥ 5 days weekly use of either menthol or non-menthol cigarettes over the past 3 months)\n* Willing to provide informed consent and abstain from using nicotine products 12 hours before each visit\n* Willing to bring UBC to each study visit\n* Read, write and speak English\n\nExclusion Criteria:\n\n* Current use of other non-combustible nicotine products (e.g., electronic \\[e\\]-cigarettes, HTPs; \\[defined as ≥ 5 days weekly use in the past 30 days\\])\n* Planning to quit nicotine use and\u002For use of any smoking cessation medication in the past 30 days\n* Current diagnosis of any lung diseases (e.g., asthma, cystic fibrosis, or chronic obstructive pulmonary disease)\n* Self-reported unstable or significant psychiatric conditions (past\u002Fstable conditions will be allowed)\n* History of cardiac event or distress within the past 3 months\n* Deaf, hard of hearing, or have a severe motor disability\n* Are currently pregnant, planning to become pregnant, or breastfeeding (urine pregnancy test will be completed at each visit throughout the study)",true,"ALL","21 Years","65 Years",{"count":77,"type":78},30,"ESTIMATED","INTERVENTIONAL",[81],"NA","This clinical trial aims to evaluate user sensory experiences and smoking behavior when using IQOS heated tobacco products (HTPs) among adults who smoke cigarettes.",[84],"Tobacco","NOT_YET_RECRUITING","2026-08-05",{"date":88,"type":89},"2026-08-10","ACTUAL",{"date":91,"type":78},"2026-08",{"date":93,"type":78},"2027-10",{"name":5,"class":6},1]