[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100648413":3},{"organization":4,"outcomesModule":7,"designInfo":19,"detailedDescription":18,"studyPopulation":18,"armGroups":28,"interventions":41,"overallOfficials":18,"centralContacts":51,"locations":57,"responsibleParty":70,"collaborators":18,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":18,"maxAge":18,"enrollmentInfo":82,"targetDuration":18,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":94,"whyStopped":18,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Universitas Sumatera Utara","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":18},[9],{"measure":10,"description":11,"timeFrame":12},"Nutritional status","This study evaluated changes in BMI, following one month of Channa striata and Curcuma supplementation.","baseline post intervention 4 weeks",[14],{"measure":15,"description":16,"timeFrame":17},"interleukin - 6","Change in serum interleukin-6 (IL-6) concentration from baseline to 1 month after daily supplementation with Channa striata and Curcuma in patients with breast cancer undergoing chemotherapy","Baseline and 1 month after intervention",null,{"allocation":20,"interventionModel":21,"interventionModelDescription":18,"primaryPurpose":22,"observationalModel":18,"timePerspective":18,"maskingInfo":23},"RANDOMIZED","PARALLEL","SUPPORTIVE_CARE",{"masking":24,"maskingDescription":18,"whoMasked":25},"DOUBLE",[26,27],"PARTICIPANT","INVESTIGATOR",[29,35],{"label":30,"type":31,"description":32,"interventionNames":33},"experimental : channa striata and curcuma","EXPERIMENTAL","intervention group",[34],"Dietary Supplement: channa striata and curcuma",{"label":36,"type":37,"description":38,"interventionNames":39},"control","PLACEBO_COMPARATOR","control group",[40],"Dietary Supplement: Maltodextrin (Placebo)",[42,47],{"type":43,"name":44,"description":45,"armGroupLabels":46,"otherNames":18},"DIETARY_SUPPLEMENT","channa striata and curcuma","Participants in the intervention group received oral supplementation consisting of 5 g of Channa striata and 250 mg of Curcuma daily for one month, while participants in the control group received a maltodextrin placebo daily for the same duration.",[30],{"type":43,"name":48,"description":49,"armGroupLabels":50,"otherNames":18},"Maltodextrin (Placebo)","Participants in the control group received a placebo consisting of maltodextrin daily for one month.",[36],[52],{"name":53,"role":54,"phone":55,"phoneExt":18,"email":56},"Damayanti Tridah Ayu","CONTACT","628116816444","damayantitridahayu@gmail.com",[58],{"facility":59,"status":18,"city":60,"state":61,"zip":18,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":18},"Nutrition Department","Medan","North Sumatera","Indonesia","ID",{"type":65,"coordinates":66},"Point",[67,68],98.66667,3.58333,{"lat":68,"lon":67},{"type":71,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","DINA KEUMALA SARI","Prof","100648413","the-effect-of-channa-striata-and-curcuma-supplementation-on-nutritional-status-interleukin-6-levels-and-quality-of-life-in-patients-with-breast-cancer-100648413",false,"NCT07722156","The Effect of Channa Striata and Curcuma Supplementation on Nutritional Status, Interleukin-6 Levels, and Quality of Life in Patients With Breast Cancer.","CCBreast","Inclusion Criteria:\n\n* Female patients with breast cancer aged ≥18 years who were undergoing chemotherapy.\n* Patients with a body mass index (BMI) of 18-29 kg\u002Fm².\n* Patients currently receiving chemotherapy for breast cancer.\n* Patients with serum albumin levels of 2.0-3.5 g\u002FdL.\n* Patients who were able to consume oral food and were willing to participate in the study by providing written informed consent.\n\nExclusion Criteria:\n\n* Patients with chronic kidney disease, renal failure, or kidney infection.\n* Patients with a known allergy to fish or Channa striata (snakehead fish) albumin-derived products.\n* Patients receiving other protein or amino acid supplements during the study period.\n* Patients who were non-compliant or discontinued the intervention before completion of the study.","FEMALE",{"count":83,"type":84},76,"ESTIMATED","INTERVENTIONAL",[87],"NA","Breast cancer is frequently accompanied by chronic inflammation, malnutrition, and reduced quality of life, all of which may compromise treatment response and clinical outcomes. Nutritional interventions with immunomodulatory and anti-inflammatory properties have the potential to improve these conditions. Channa striata is rich in high-quality protein, albumin, and essential amino acids that support nutritional recovery and tissue repair, while Curcuma contains curcumin, a bioactive compound with well-established anti-inflammatory and antioxidant effects. This study aims to evaluate the effect of combined Channa striata and Curcuma supplementation on nutritional status, serum interleukin-6 (IL-6) levels, and quality of life in patients with breast cancer undergoing treatment. The findings are expected to provide evidence for the use of this nutritional supplementation as a complementary strategy to improve clinical outcomes, reduce systemic inflammation, and enhance the overall well-being of breast cancer patients.",[90],"Breast Cancer",[92,93],"Breast cancer; Channa striata; Curcuma; Nutritional status; Interleukin-6 (IL-6); Quality of life; Nutritional supplementation; Inflammation.","Breast cancer, Channa striata Curcuma, Interleukin-6, Quality of life","NOT_YET_RECRUITING","2026-07-19",{"date":97,"type":98},"2026-07-23","ACTUAL",{"date":100,"type":84},"2026-08-01",{"date":102,"type":84},"2027-01-31",{"name":72,"class":6},1]